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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine

Product Name
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
CAS No.
1638499-31-6
Chemical Name
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
Synonyms
Tofacitinib-4;Tofatinib Impurity 35;Nicotinamide Impurity 114;Tofacitinib Impurity J 2HCl;3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-;(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity);Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
CBNumber
CB53154815
Molecular Formula
C14H22N2
Formula Weight
218.34
MOL File
1638499-31-6.mol
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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Property

Boiling point:
302.6±35.0 °C(Predicted)
Density 
1.00±0.1 g/cm3(Predicted)
pka
10.26±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B276215
Product name
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Packaging
2.5mg
Price
$330
Updated
2021/12/16
TRC
Product number
B276215
Product name
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Packaging
25mg
Price
$2640
Updated
2021/12/16
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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Chemical Properties,Usage,Production

Uses

(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Suppliers

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1638499-31-6, (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amineRelated Search:

4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide 2,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile 4-METHYL-3-METHYLAMINOPYRIDINE 3-Piperidinamine,4-methyl-1-(phenylmethyl)-,(3R,4R)-rel- Tofacitinib impurity T N-Hydroxysuccinimide 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine methyl3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin -4-yl)amino)piperidin-1-yl)-3-oxopropanoate Methyl (4-Methylpiperidin-3-yl)carbaMate 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)- (3R,4R)-N,4-dimethyl-piperidin-3-amine 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile CYANOACETIC ACID-OSU

  • Tofacitinib-4
  • Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
  • (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity)
  • 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-
  • Tofatinib Impurity 35
  • Nicotinamide Impurity 114
  • Tofacitinib Impurity J 2HCl
  • 1638499-31-6