ChemicalBook > CAS DataBase List > 2-Deoxy-D-ribose

2-Deoxy-D-ribose

Product Name
2-Deoxy-D-ribose
CAS No.
533-67-5
Chemical Name
2-Deoxy-D-ribose
Synonyms
Deoxyribose;D-2-DEOXYRIBOSE;THYMINOSE;2-DEOXYRIBOSE;D-erythro-Pentose, 2-deoxy-;(3S,4R)-3,4,5-trihydroxypentanal;desoxyribose;D-deoxyribose;(2R,4S,5R)-5-(hydroxyMethyl)tetrahy-drofuran-2,4-diol;ribodesose
CBNumber
CB5315585
Molecular Formula
C5H10O4
Formula Weight
134.13
MOL File
533-67-5.mol
More
Less

2-Deoxy-D-ribose Property

Melting point:
89-90 °C(lit.)
alpha 
-57 º (c=1, H2O, 24hr)
Boiling point:
167.23°C (rough estimate)
Density 
1.0590 (rough estimate)
refractive index 
-56 ° (C=1, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
form 
Crystalline Powder
pka
12.61(at 25℃)
color 
White to slightly yellow
optical activity
[α]22/D 59°, c = 1 in H2O
Water Solubility 
soluble
Sensitive 
Hygroscopic
Merck 
14,2908
BRN 
1721978
Stability:
Hygroscopic
InChIKey
ASJSAQIRZKANQN-CRCLSJGQSA-N
CAS DataBase Reference
533-67-5(CAS DataBase Reference)
NIST Chemistry Reference
D-Erythro-pentose, 2-deoxy-(533-67-5)
EPA Substance Registry System
D-erythro-Pentose, 2-deoxy- (533-67-5)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-37/39-36-26
WGK Germany 
3
RTECS 
SB7230000
F 
3-10
TSCA 
Yes
HS Code 
29400000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
31170
Product name
2-Deoxy-D-ribose
Purity
≥99.0% (TLC)
Packaging
5G
Price
$110
Updated
2025/07/31
Sigma-Aldrich
Product number
121649
Product name
2-Deoxy-D-ribose
Purity
97%
Packaging
1g
Price
$25.5
Updated
2025/07/31
Sigma-Aldrich
Product number
31170
Product name
2-Deoxy-D-ribose
Purity
≥99.0% (TLC)
Packaging
25g
Price
$334
Updated
2025/07/31
Sigma-Aldrich
Product number
31170
Product name
2-Deoxy-D-ribose
Purity
≥99.0% (TLC)
Packaging
1g
Price
$33.1
Updated
2024/03/01
TCI Chemical
Product number
D0059
Product name
2-Deoxy-D-ribose
Purity
>98.0%(HPLC)
Packaging
5g
Price
$33
Updated
2025/07/31
More
Less

2-Deoxy-D-ribose Chemical Properties,Usage,Production

Description

2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase. It increases levels of reactive oxygen species (ROS) in HL-60 human leukemia cells when used at a concentration of 15 mM. 2-deoxy-D-Ribose (10 μM) induces tubulogenesis and migration of bovine aortic endothelial (BAE) cells. Topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model.

Uses

2-Deoxy-D-ribose (2dDR) can be used to prepare multifunctional wound dressings capable of inducing rapid angiogenesis with antimicrobial activity, such as 2dDR-SA hydrogel. The gel can be used to stimulate wound healing and treat superficial skin wounds, including chronic wound care. In addition, 2dDR gel has the potential to treat androgenetic alopecia and other causes of alopecia areata.

Uses

2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Definition

ChEBI: 2-deoxy-D-ribose is a deoxypentose that is D-ribose in which the hydroxy group at position C-2 is replaced by hydrogen. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a D-ribose.

benefits

Hair Regrowth in Mice: Applying a small dose of 2-deoxy-D-ribose to mice models led to significant hair regrowth.
Blood Vessel Formation: The hair regrowth was linked to forming new blood vessels, enhancing blood supply to hair follicles.
Comparable to Minoxidil: The effectiveness of 2-deoxy-D-ribose in regrowing hair was similar to that of Minoxidil, a widely used hair loss treatment.

Biological Activity

2-Deoxy-D-ribose (2dDR) is a D-isomer of a deoxypentose monosaccharide in which a hydrogen atom is present with a hydroxyl group at the C-2 position in place of the hydroxyl group. 2dDR is known to enhance tubulogenesis, prevent hypoxia-induced apoptosis, and boost VEGF and IL-8 production of ECs in vitro, consistent with the stimulatory effects of 2dDR on cell proliferation and migration. 2dDR also stimulated angiogenesis, proliferation of endothelial cells, and accelerated wound healing in rat models. Additionally, 2dDR can be loaded into several biomaterials for prolonged release over several days to promote the growth of neonatal blood vessels[1].

References

[1] Anjum, Muhammad Awais et al. “Stimulation of hair regrowth in an animal model of androgenic alopecia using 2-deoxy-D-ribose.” Frontiers in Pharmacology 44 16 (2024).

2-Deoxy-D-ribose Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Deoxy-D-ribose Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 622 Europe 3 France 2 Germany 12 India 23 Italy 1 Japan 6 Poland 1 Slovakia 1 South Korea 1 Switzerland 6 The Netherlands 1 United Kingdom 22 United States 80 Global 787
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Advent Bio, Inc.
Tel
(630) 889-9003
Fax
(630) 889-9021
Email
sales@adventbio.com
Country
United States
ProdList
61
Advantage
60
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19654
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
+86-020-81960175-877 4000-868-328
Email
tianwen.zhan@cato-chem.com
Country
United States
ProdList
10404
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
CAMBRIDGE ISOTOPE LABORATORIES INC
Tel
--
Fax
--
Email
intlsales@isotope.com
Country
United States
ProdList
5
Advantage
58
Abcam Limited
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6001
Advantage
50
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Advanced Synthesis S.A.
Tel
--
Fax
--
Country
United States
ProdList
249
Advantage
58
Wilshire Technologies
Tel
--
Fax
--
Country
United States
ProdList
428
Advantage
58
Wilshire Technologies, Inc.
Tel
--
Fax
--
Email
info@wilshiretechnologies.com
Country
United States
ProdList
893
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Pharnorcia Inc. US
Tel
--
Fax
--
Email
info@pharnorcia.com
Country
United States
ProdList
112
Advantage
34
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
Spectrum Chemical Mfg. Corp.
Tel
--
Fax
--
Email
marketing@spectrumchemical.com
Country
United States
ProdList
3113
Advantage
60
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
W & J PharmaChem, Inc.
Tel
--
Fax
--
Email
info@wjpharmachem.com
Country
United States
ProdList
595
Advantage
50
Omicron Biochemicals, Inc.
Tel
--
Fax
--
Email
omicron@omicronbio.com
Country
United States
ProdList
580
Advantage
64
Louston International
Tel
--
Fax
--
Email
sales@louston.com
Country
United States
ProdList
525
Advantage
58
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
More
Less

View Lastest Price from 2-Deoxy-D-ribose manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Deoxy-D-ribose 533-67-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2025-08-29
HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
2-Deoxy-D-ribose 533-67-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20tons
Release date
2025-08-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Deoxy-D-ribose 533-67-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-05-16

533-67-5, 2-Deoxy-D-riboseRelated Search:

Ribose L-Arabinopyranose D-Ribose Digitoxin CYMARIN D-(+)-DIGITOXOSE SEDOHEPTULOSE ANHYDRIDE D-(+)-TURANOSE CHROMOMYCIN A3 D-GALACTURONIC ACID LANATOSIDE A DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* 2-DEOXY-L-RIBOSE,2-DEOXY-L-RIBOSE 99% MUCIC ACID GITOXIN LANATOSIDE B 4-METHYLUMBELLIFERYL-ALPHA-L-FUCOPYRANOSIDE DIGOXIN

  • D-.alpha.-Ribodesose
  • Deoxyribose
  • D-Ribose, 2-deoxy-
  • 2-deoxy-d-erythro-pentos
  • 2-Deoxypentose
  • 2-Desoxy ribosoe
  • D-(-)-2-DEOXYRIBOSE
  • D-2-DEOXYRIBOSE
  • D-2-DESOXYRIBOSE
  • 2-Deoxy-beta-D-erythro-pentose
  • Deoxy-D-Ribose
  • 2-DEOXY-D-RIBOSE CELL CULTURE TESTED
  • 2-Deoxy-D-Ribose98.0%Min
  • 2-Deoxy-D-ribose,99%
  • 2-DEOXY-D-RIBOSE (D-REYTHRO-2-DEOXYPENTOSE)
  • D-erythro-Pentose, 2-deoxy-
  • 2-DEOXY-D-RIBOSE,CRYSTALLINE
  • 3,4,5-trihydroxypentanal
  • desoxyribose
  • ribodesose
  • 2-DEOXY-D-RIBOSE BR
  • D-erythro-Pentose, 2-deoxy- 533-67-5
  • 2-Deoxy-D-riboside
  • 2-Doxy-D-Ribose
  • 2-DEOXY-D-RIBOSE extrapure
  • 2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose
  • Ribose, 2-deoxy-, D-
  • 2-DEOXYRIBOSE
  • 2-DESOXY-D-RIBOSE
  • 2-DEOXY-D-RIBOSE
  • 2-DEOXY-D-ARABINOSE
  • 2-DEOXY-D-ERYTHRO-PENTOSE
  • D-ERYTHRO-2-DEOXYPENTOSE
  • DEOXY-D-RIBOSE,2-
  • TETRAHYDRO-2H-PYRAN-2,4,5-TRIOL
  • THYMINOSE
  • .alpha.-Deoxy-D-ribose
  • (2S,4S,5R)-Oxane-2,4,5-triol
  • D-deoxyribose
  • 2-Deoxy-D-riboside >99%
  • (3S,4R)-3,4,5-trihydroxypentanal
  • (2R,4S,5R)-5-(hydroxyMethyl)tetrahy-drofuran-2,4-diol
  • 2-Deoxy-D-ribose 97%
  • Cladribine Impurity E
  • NAPTHALENE NEAT
  • 2-Deoxy-D-ribose (Zidovudine)
  • 2-Deoxy-D-arabinose, low endotoxin ≤10 EU/mg
  • 2-Deoxy-D-erythro-pentose, low endotoxin ≤10 EU/mg
  • 2-Deoxy-D-ribose, low endotoxin ≤10 EU/mgCell culture grade, ≥ 99% (HPLC)
  • Cladribine Impurity 5(Cladribine EP Impurity E)
  • (2S,4S,5R)-5-(hydroxymethyl)oxolane-2,4-diol
  • Cladribine EP Impurity E
  • 2DR(2-Deoxy-D-ribose)
  • 2-Deoxy-D-ribose &gt
  • 2'-Deoxy-D-RMbose,≥98%
  • (4S,5R)-Oxane-2,4,5-triol
  • 2-Deoxy-D-ribose USP/EP/BP
  • dextro-2-deoxyribose