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Rivaroxaban Impurity 27

Product Name
Rivaroxaban Impurity 27
CAS No.
1369969-44-7
Chemical Name
Rivaroxaban Impurity 27
Synonyms
Rivaroxaban Impurity 27;Rivaroxaban Phthalimide;(S)-Rivaroxaban Impurity 107;2-[(2S)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-;(S)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione? (Rivaroxaban Impurity);Rivaroxaban Impurity 13/2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
CBNumber
CB53159274
Molecular Formula
C21H21N3O5
Formula Weight
395.41
MOL File
1369969-44-7.mol
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Rivaroxaban Impurity 27 Property

Boiling point:
734.9±60.0 °C(Predicted)
Density 
1.421±0.06 g/cm3(Predicted)
storage temp. 
-10 to -25°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
13.91±0.20(Predicted)
color 
White to Off-White
Major Application
pharmaceutical small molecule
InChI
1S/C21H21N3O5/c25-16(12-24-20(27)17-3-1-2-4-18(17)21(24)28)11-22-14-5-7-15(8-6-14)23-9-10-29-13-19(23)26/h1-8,16,22,25H,9-13H2/t16-/m0/s1
InChIKey
CKFVSMPWXAASIQ-INIZCTEOSA-N
SMILES
N4(CCOCC4=O)c1ccc(cc1)NC[C@H](O)CN2C(=O)c3c(cccc3)C2=O
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
H951190
Product name
2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
Packaging
2.5g
Price
$1455
Updated
2021/12/16
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Rivaroxaban Impurity 27 Chemical Properties,Usage,Production

Uses

2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent.

Rivaroxaban Impurity 27 Preparation Products And Raw materials

Raw materials

Preparation Products

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1369969-44-7, Rivaroxaban Impurity 27Related Search:


  • Rivaroxaban Impurity 13/2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
  • Rivaroxaban Impurity 27
  • 2-[(2S)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
  • (S)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione? (Rivaroxaban Impurity)
  • Rivaroxaban Phthalimide
  • (S)-Rivaroxaban Impurity 107
  • 1369969-44-7