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(S)-(+)-Glycidyl Phthalimide

Product Name
(S)-(+)-Glycidyl Phthalimide
CAS No.
161596-47-0
Chemical Name
(S)-(+)-Glycidyl Phthalimide
Synonyms
PHTHAL;(S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE;S-Glycidyl Phthalamide;(S)-N-Glycidylphthalimide;2-[[(2S)-oxiran-2-yl]methyl]isoindoline-1,3-dione;2-[(2S)-ox;(S)-(+)-GL;2-Amino-8-picoline;Rivaroxaban Impurity R;Linezolid EPP Impurity
CBNumber
CB7273483
Molecular Formula
C11H9NO3
Formula Weight
203.19
MOL File
161596-47-0.mol
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(S)-(+)-Glycidyl Phthalimide Property

Melting point:
102 °C
Boiling point:
347.4±15.0 °C(Predicted)
Density 
1.446±0.06 g/cm3(Predicted)
vapor pressure 
0.001-2.17Pa at 25-90.25℃
refractive index 
10 ° (C=2.2, CHCl3)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
-2.24±0.20(Predicted)
form 
Solid
color 
White
InChI
InChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1
InChIKey
DUILGEYLVHGSEE-ZETCQYMHSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H]1CO1
LogP
1.2 at 40℃
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-39
WGK Germany 
2
HS Code 
29252900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
671606
Product name
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide
Purity
≥99.0% (GC)
Packaging
1g
Price
$31.4
Updated
2023/06/20
TCI Chemical
Product number
G0328
Product name
(S)-N-Glycidylphthalimide
Purity
>98.0%(GC)
Packaging
5g
Price
$49
Updated
2024/03/01
TCI Chemical
Product number
G0328
Product name
(S)-N-Glycidylphthalimide
Purity
>98.0%(GC)
Packaging
25g
Price
$140
Updated
2024/03/01
TRC
Product number
G615960
Product name
N-(S)-Glycidylphthalimide
Packaging
25g
Price
$215
Updated
2021/12/16
Chem-Impex
Product number
39547
Product name
(S)-N-Glycidylphthalimide,≥98%(GC)
Purity
≥98%(GC)
Packaging
5G
Price
$36.11
Updated
2021/12/16
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(S)-(+)-Glycidyl Phthalimide Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

(S)-(+)-Glycidyl Phthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500). It is also a key intermediate of rivaroxaban.

Synthesis

Phthalimide and (S)-1-substituent propylene oxide are used as raw materials, a reaction occurs under the action of a catalyst to generate 2-((S)-3-substituent-2-hydroxypropyl isodihydroindole-1,3-dione, and finally (S)-glycidyl phthalimide is generated by means of a ring-closure reaction.

(S)-(+)-Glycidyl Phthalimide Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(+)-Glycidyl Phthalimide Suppliers

Bayee Biotech (Anqing) Co., Ltd.
Tel
0556-5032306 18917961636
Fax
+86-556-5032307
Email
wtx@bayeebio.com
Country
China
ProdList
265
Advantage
61
Shanghai Prescrina Pharmaceutical Technology Co., LTD
Tel
18367323072
Email
2125193158@qq.com
Country
China
ProdList
367
Advantage
58
Jilin Lianben Technology Development Co., Ltd
Tel
13756693631
Fax
0432-62601618
Email
sunting@lianben.com
Country
China
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46
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58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82375886 13001715031
Fax
0531-82375893
Email
3517280075@qq.com
Country
China
ProdList
1274
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58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
969
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68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
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61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
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View Lastest Price from (S)-(+)-Glycidyl Phthalimide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide 161596-47-0
Price
US $0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
10kg/month
Release date
2021-12-17
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
(S)-(+)-Glycidyl Phthalimide 161596-47-0
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000Ton
Release date
2024-08-13
Hebei Dangtong Import and export Co LTD
Product
(S)-(+)-GLYCIDYL PHTHALIMIDE 161596-47-0
Price
US $300.00-260.00/kg
Min. Order
100kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-06

161596-47-0, (S)-(+)-Glycidyl PhthalimideRelated Search:


  • (S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE
  • (S)-(+)-GLYCIDYL PHTHALIMIDE
  • (S)-GLYCIDYL PHTHALIMIDE
  • 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione
  • Rivaroxaban Impurity 39
  • 2-((2S)-OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
  • (S)-(+)-N-(2,3-Epoxypropyl)phthalimide
  • (S)-N-Glycidylphthalimide
  • 2-[(2S)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
  • Rivaroxaban Intermediate 2
  • 2-[(2S)-ox
  • 2-[(2S)-2-oxiranyl Methyl]-1H-isoindole-1,3(2H)-dione
  • (2S)-2-(OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
  • (S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE (S)-(+)-GLYCIDYL PHTHALIMIDE (S)-GLYCIDYL PHTHALIMIDE 2-((2S)-OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
  • 2-[(2S)-ox 2-[(2S)-2-oxiranyl Methyl]-1H-isoindole-1,3(2H)-dione
  • (S)-4-(oxiran-2-ylMethyl)isoindoline-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylMethyl]-
  • N-(S)-Glycidylphthalimide
  • (S)-(+)-N-(2,3-Epoxypropyl)pthalaMide
  • (S)-N-GlycidylphthaliMide, ee: 97.5%
  • (S)-(+)-N-(2,3-Epoxypropyl)phthaliMide >=99.0% (GC)
  • (S)-N-GlycidylphthaliMide, ee: 98%
  • (S)-(+)-GLYCIDYL PHTHALIdime
  • (S)-N-Glycidylphthalimide, 98.5%, ee: 97.5%
  • (S)-N-Glycidylphthalimide, 98.5%, ee: 98%
  • PHTHAL
  • Rivaroxaban Impurity R
  • Linezolid EPP Impurity
  • 2-{[(2S)-oxiran-2-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione
  • (S)-(+)-GLYCIDYL PHTHALIMIDEONE
  • (S)-N-Glycidylphthalimide&gt
  • (S)-(+)-GL
  • S-Glycidyl Phthalamide
  • (S)-(+)-GLYCIDYL PHTHALIMIDE ISO 9001:2015 REACH
  • Rivaroxaban intermediates,(S)-(+)-Glycidyl Phthalimide
  • (S)- (+) - (2,3-Epoxypropyl) phthalimide
  • 2-Amino-8-picoline
  • 2-[[(2S)-oxiran-2-yl]methyl]isoindoline-1,3-dione
  • (S)-N-Glycidylphthalimide, ≥99%
  • (s)-2-oxiranylmethyl-isoindole-1,3-dione/(S)-(+)-Glycidyl Phthalimide
  • (2S)-2-Oxiranylmethyl-isoindole-1,3-dione
  • (S)-2-Oxiranylmethyl-isoindole-1,3-dione (or) (S) (+)- Glycidyl Phthalimide
  • S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-ion
  • 2-[(2s)-oxirane-2yl methyl]-1H-isoindole-1,3(2H)-dione
  • ( S ) -2- ( Oxiran - 2 - ylmethyl ) -1H - isoindole - 1,3 ( 2H ) dione
  • (S)-Glycidyl Phthalimide or (S)-2-(oxiran-2-ylmethyl)isoindoline-1,3-dione
  • 2-(((S)-Oxiran-2yl)Methyl)Isoindoline-1,3-Dione
  • (S)-2-(oxiran-2-ylmethyl isoindoline-1,3-dione (or) (S)-N-Glycidylphthalimide
  • (S)-N-Glycidylphthalimide, ≥ 98.0%
  • (S)-(+)-N-(2,3-Epoxypropyl)phthalimide or (S)-N-Glycidylphthalimide
  • 161596-47-0
  • 161592-47-0
  • 61596-47-0
  • Intermediate of Rivaroxaban
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • Oxiranes
  • Simple 3-Membered Ring Compounds