ChemicalBook > CAS DataBase List > 1,3-Adamantanedicarboxylic acid

1,3-Adamantanedicarboxylic acid

Product Name
1,3-Adamantanedicarboxylic acid
CAS No.
39269-10-8
Chemical Name
1,3-Adamantanedicarboxylic acid
Synonyms
ADAMANTANE-1,3-DICARBOXYLIC ACID;(1s,3s,5r,7r)-AdaMantane-1,3-dicarboxylic acid;AKOS BC-0656;1,3-DICARBOXYADAMANTANE;adamantane-1,3-dicarboxylate;1,3-ADAMANTANEDICARBOXYLIC ACID;1,3-Adamantanedicarboxylic Acid >1,3-Adamantanedicarboxylic acid 98%;Tricyclo[3.3.1.13,7]decane-1,3-dicarboxylic acid;tricyclo(3.3.1.1(sup3,7))decane-1,3-dicarboxylicacid
CBNumber
CB5316047
Molecular Formula
C12H16O4
Formula Weight
224.25
MOL File
39269-10-8.mol
More
Less

1,3-Adamantanedicarboxylic acid Property

Melting point:
276-278 °C (lit.)
Boiling point:
380.6±15.0 °C(Predicted)
Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated)
form 
Solid
pka
4.24±0.40(Predicted)
color 
White to Off-White
CAS DataBase Reference
39269-10-8(CAS DataBase Reference)
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
YD1994000
HS Code 
29172090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
340820
Product name
1,3-Adamantanedicarboxylic acid
Purity
98%
Packaging
1G
Price
$120
Updated
2023/01/07
TCI Chemical
Product number
A1358
Product name
1,3-Adamantanedicarboxylic Acid
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$73
Updated
2024/03/01
TCI Chemical
Product number
A1358
Product name
1,3-Adamantanedicarboxylic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$246
Updated
2024/03/01
Alfa Aesar
Product number
H60081
Product name
Adamantane-1,3-dicarboxylic acid, 98%
Packaging
1g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
H60081
Product name
Adamantane-1,3-dicarboxylic acid, 98%
Packaging
5g
Price
$211.65
Updated
2024/03/01
More
Less

1,3-Adamantanedicarboxylic acid Chemical Properties,Usage,Production

Uses

1,3-Adamantanedicarboxylic acid is a carboxylic acid derivative of adamantane. It is widely used in drug industry, polymer synthesis and fine chemicals as key intermediates. It is also used as antidepressants or antiparkinsonic drugs in clinical practice.

Preparation

1,3-Adamantanedicarboxylic acid was synthesized from 1-adamantane carboxylic acid by one-pot method. In this process, the ratio of mixed acid (nitric acid and sulfuric acid) have important effect on the yield, the role of sulfuric acid not only is solvent, but also can improve the oxidate ability of nitric acid.
Efficient Synthesis of 1,3-Adamantanedicarboxylic Acid and 1,3-Diaminoadamantane

Reaction: 1-Adamantane carboxylic acid (20 g), nitric acid (65 %, 20 mL) and sulfuric acid (98 %, 160 mL) were placed in a three-necked roundbottom flask fitted with an efficient magnetic stirrer and a thermometer. Cooled to 0 oC and held at 0 oC, anhydrous formic acid (80 %, 70 mL) was added dropwise in 5 h and reacted for 1 h. poured to crushed ice, filtered and then washed the precipitate several times with water to give a white solid. Then the white solid was dissolved in aqueous NaOH solution and the upper clear solution was separated and acidified by HCl to pH = 3. Filtered, washed with water, dried in vacuum, recrystallized from ethanol. White solid, yield 22.9 g (92 %). m.p.: 275- 276 oC
1H NMR (DMSO-d6, 400 MHz) δ: 1.616 (m, 2H), 1.691-1.727 (m, 4H), 1.759-1.791 (m, 4H), 1.850-1.882 (m, 2H), 2.059 (m, 1H), 12.062 (br, s, 2H, COOH); 13C NMR (100 MHz, DMSO-d6) δ 27.37 (C-5, C-7), 34.98 (C-6), 37.66 (C-4, C-8, C-9, C-10), 39.78 (C-2), 39.89 (C-2, C-3), 177.76 (COOH). IR (KBr, νmax, cm-1) : 2913, 2851, 2636, 1691, 1451, 1410, 1344, 1249, 1103, 1084, 952, 743, 670, 528; Anal. calcd for C12H16O4: C 64.29, H 7.14; found C 64.55, H 7.22.

Purification Methods

Dissolve the acid in aqueous NaOH, treat with charcoal, filter and acidify with dilute HCl. It crystallises from MeOH. [Stetter & Wulff Chem Ber 93 1366 1960, Beilstein 9 III 4066, 9 IV 2997.]

1,3-Adamantanedicarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,3-Adamantanedicarboxylic acid Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Atlantic Research Chemicals Ltd.
Tel
--
Fax
--
Email
info@atlantic-chemicals.com
Country
United Kingdom
ProdList
5618
Advantage
63
ETA SCIENTIFIC Co.,Ltd
Tel
--
Fax
--
Email
sales@etascientific.com
Country
United Kingdom
ProdList
6090
Advantage
34
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
Zerenex Molecular Limited
Tel
--
Fax
--
Email
sales@zerenex-molecular.com
Country
United Kingdom
ProdList
6204
Advantage
47
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
More
Less

View Lastest Price from 1,3-Adamantanedicarboxylic acid manufacturers

Shanghai Qyubiotech Co., Ltd.
Product
1,3-Adamantanedicarboxylic acid 39269-10-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
97%+
Supply Ability
10000kgs per Month
Release date
2023-04-19
Career Henan Chemical Co
Product
1,3-Adamantanedicarboxylic acid 39269-10-8
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-21

39269-10-8, 1,3-Adamantanedicarboxylic acidRelated Search:


  • adamantane-1,3-dicarboxylate
  • tricyclo(3.3.1.1(sup3,7))decane-1,3-dicarboxylicacid
  • ADAMANTANE-1,3-DICARBOXYLIC ACID
  • AKOS BC-0656
  • 1,3-ADAMANTANEDICARBOXYLIC ACID
  • 1,3-DICARBOXYADAMANTANE
  • Tricyclo[3.3.1.13,7]decane-1,3-dicarboxylic acid
  • (1s,3s,5r,7r)-AdaMantane-1,3-dicarboxylic acid
  • 1,3-AdaMantanedicarboxylic acid SynonyMs AdaMantane-1,3-dicarboxylic acid
  • 1,3-Adamantanedicarboxylic acid 98%
  • 1,3-Adamantanedicarboxylic Acid &gt
  • 39269-10-8
  • Adamantanes
  • Carboxylic Acids
  • Fused Ring Systems
  • Alicyclic/Etch-Resistant MonomersPolymer Science
  • Carboxylic Acid Monomers
  • Lithography Monomers
  • Monomers
  • Self Assembly&Contact Printing
  • Adamantane derivatives
  • Carboxylic Acids
  • Adamantanes