3-Amino-6-morpholinopyridine
- Product Name
- 3-Amino-6-morpholinopyridine
- CAS No.
- 52023-68-4
- Chemical Name
- 3-Amino-6-morpholinopyridine
- Synonyms
- AKOS B034244;BUTTPARK 99\12-14;OTAVA-BB BB7018930038;6-MORPHOLINOPYRIDIN-3-AMINE;6-MORPHOLINO-3-PYRIDINAMINE;3-AMINO-6-MORPHOLINOPYRIDINE;6-Morpholinopyridine-3-amine;6-Morpholinopyridine-3-Amino;5-Amino-2-morpholinopyridine;6-MORPHOLIN-4-YLPYRIDIN-3-AMINE
- CBNumber
- CB5320215
- Molecular Formula
- C9H13N3O
- Formula Weight
- 179.22
- MOL File
- 52023-68-4.mol
3-Amino-6-morpholinopyridine Property
- Melting point:
- 126-128°C
- Boiling point:
- 414.4±45.0 °C(Predicted)
- Density
- 1.208±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 6.48±0.10(Predicted)
- Appearance
- Brown to black Solid
- CAS DataBase Reference
- 52023-68-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-22
- Safety Statements
- 22-36/37/39-36/37
- RIDADR
- 2811
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M725250
- Product name
- 6-Morpholinopyridin-3-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H30-1-V0
- Product name
- 5-Amino-2-(morpholin-4-yl)pyridine
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 4H30-1-V0
- Product name
- 5-Amino-2-(morpholin-4-yl)pyridine
- Packaging
- 5G
- Price
- $536
- Updated
- 2021/12/16
- Product number
- CHM0068561
- Product name
- 3-AMINO-6-MORPHOLINOPYRIDINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $615.34
- Updated
- 2021/12/16
- Product number
- 4H30-1-V0
- Product name
- 5-Amino-2-(morpholin-4-yl)pyridine
- Packaging
- 25g
- Price
- $1484
- Updated
- 2021/12/16
3-Amino-6-morpholinopyridine Chemical Properties,Usage,Production
Uses
5-Amino-2-(4-morpholinyl)pyridine is used as pharmaceutical intermediate.
Synthesis
26820-62-2
52023-68-4
General procedure for the synthesis of 3-amino-6-morpholinopyridine from 4-(5-nitropyridin-2-yl)morpholine: a mixture of 1.65 g (7.8 mmol) of 4-(5-nitro-2-pyridinyl)morpholine, 160 mg of 5% Pt/C catalyst, and 20 mL of ethanol was placed in a reactor. The reaction was carried out under 50 psi hydrogen atmosphere for 5 hours. Upon completion of the reaction, the mixture was filtered through a pad of diatomaceous earth to remove the catalyst, followed by evaporation of the solvent under reduced pressure to afford 1.4 g (100% yield) of 6-(4-morpholino)-3-pyridinamine, the product being a purple solid. Its 1H NMR (400 MHz, DMSO-d6) data were as follows: δ 7.60 (d, J=2.9 Hz, 1H), 6.92 (dd, J=8.8 and 2.9 Hz, 1H), 6.62 (d, J=8.8 Hz, 1H), 4.59 (brs, 2H), 3.65-3.72 (m, 4H), 3.17 (dt, J= 4.9 and 2.4 Hz, 4H).
References
[1] Patent: WO2009/32667, 2009, A1. Location in patent: Page/Page column 148
[2] Patent: WO2009/76140, 2009, A1. Location in patent: Page/Page column 237
[3] Patent: WO2010/104899, 2010, A1. Location in patent: Page/Page column 106
[4] Patent: WO2009/154769, 2009, A1. Location in patent: Page/Page column 35
[5] Patent: WO2014/12360, 2014, A1. Location in patent: Paragraph 00355
3-Amino-6-morpholinopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-6-morpholinopyridine Suppliers
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View Lastest Price from 3-Amino-6-morpholinopyridine manufacturers
- Product
- 6-Morpholinopyridin-3-amine 52023-68-4
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-27
- Product
- 3-Amino-6-morpholinopyridine 52023-68-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-07-03