Description
ChemicalBook > CAS DataBase List > 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

Description
Product Name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
CAS No.
22246-18-0
Chemical Name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Synonyms
7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE;7-HYDROXY-3,4-DIHYDROCARBOSTYRIL;7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE;7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;7-Hydroxy-3;AURORA KA-4813;Aripiprazole Imp.A;3,4-Dihydro-7-hydrox;7-Hydroxy carbostyril;Aripiprazole Impurity 13
CBNumber
CB5325629
Molecular Formula
C9H9NO2
Formula Weight
163.17
MOL File
22246-18-0.mol
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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Property

Melting point:
233-237 °C
Boiling point:
403.7±45.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.60±0.20(Predicted)
color 
Pale Yellow
InChIKey
LKLSFDWYIBUGNT-UHFFFAOYSA-N
CAS DataBase Reference
22246-18-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-43
Safety Statements 
36/37
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
675369
Product name
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
Purity
97%
Packaging
1g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
D3599
Product name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D3599
Product name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$40
Updated
2024/03/01
Alfa Aesar
Product number
H27485
Product name
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone, 97%
Packaging
1g
Price
$35.9
Updated
2023/06/20
TRC
Product number
D449145
Product name
3,4-Dihydro-7-hydroxyquinoline-2(1H)-one
Packaging
5g
Price
$135
Updated
2021/12/16
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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Chemical Properties,Usage,Production

Description

3,4-Dihydro-7-hydroxy-2 (1H)-quinolinone is a useful organic and pharmaceutical intermediate. It can be used as the precursor of aripiprazole1, which is an antipsychotic medication. It is also an antitumor agent and hydroxyindole analog inhibitor tyrosinase melanoma.

Chemical Properties

Pale Yellow Powder

Uses

3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000).

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Suppliers

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View Lastest Price from 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14
PNP Biotech Co. Ltd
Product
7-Hydroxy-3,4-dihydrocarbostyril 22246-18-0
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-25
Henan Fengda Chemical Co., Ltd
Product
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22

22246-18-0, 3,4-Dihydro-7-hydroxy-2(1H)-quinolinoneRelated Search:

4'-Hydroxyacetophenone CHLOROPHOSPHONAZO III Quinhydrone 2'-Hydroxyacetophenone 2-Quinolinol Tetrahydro-4H-pyran-4-one Neosperidin dihydrochalcone 1-Tetralone 8-Hydroxyquinoline Dehydroepiandrosterone 7-Hydroxyquinolinone 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE Brexpiprazole Impurity 20 Brexpiprazole Impurity 5 HCl 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE 5-HYDROXY-2(1H)-QUINOLINONE 7,7'-(butane-1,4-diylbis(oxy))bis(quinolin-2(1H)-one)

  • 7-Hydroxy-3,4-dihydro-2(1<i>H</i>)-quinolinone
  • Aripiprazole Dihydroquinolinone Impurity (USP)
  • 7-Hydroxy-3,4-dihydro-2(1H)-chinolinon
  • Intermediate of Aripiprazole
  • Aripiprazole Impurity 13
  • 7- hydroxy-3,4- twohydrogen -2(1H)- quinolinone
  • 7-Hydroxy-3,4-dihydro-2(H)-quinolinone
  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone SynonyMs 7-Hydroxy Carbostyril
  • 7-Hydroxy-1,2,3,4-tetrahydro-2-chinolinon
  • 7-HYDROXY-1,2,3,4-TETRAHYDRO-2-QUINOLINONE
  • 7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE
  • 7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE-2-ONE
  • 7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
  • 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE
  • 7-HYDROXY-3,4-DIHYDRO-2-OXO-(1H)-QUINOLINE
  • 7-HYDROXY-3,4-DIHYDROCARBOSTYRIL
  • 7-HYDROXY-3,4-DIHYDRO CARBOSTYRYL
  • 7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE
  • 7-HYDROXY-3,4-DIHYDRO-QUINOLIN-2-ONE
  • 8-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE
  • 3,4-DIHYDRO-7-HYDROXYCARBOSTYRIL
  • 7-Hydroxy-2(1H)-3,4-dihydroquinolinone
  • 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE3,4-DIHYDRO-7-HYDROXY-2-(1H)-QUINOLINONE
  • 3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone
  • 7-Hydroxy-2-Oxo-3,4-Dihydroquinoline
  • 7-Hydroxy-3,4-dihydro-2(1H)-qu
  • 3,4-DIHYDRO-7-HYDROXY-2(1H)-QUINOLINONE /7-HQ
  • 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINLINONE
  • 7-HYDROXY-3,4-DIHYDRO-2(1H)QUINOLINONE//INTERMEDIATE OF ARIPIPRAZOLE
  • AURORA KA-4813
  • (1H)-7-HYDROXY-3,4-DIHYDRO-2-QUINOLINONE
  • Aripiprazole Imp.A
  • 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 97%
  • Aripiprazole Dihydroquinolinone Impurity
  • 7-HYDROXY-2-OXO-3,4-DIHYDROQUINOLINE, 98% ARIPIPRZAOLE INTERMEDIATE
  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
  • 7-Hydroxy carbostyril
  • 7-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline
  • 2(1H)-Quinolinone,7-hydroxy, 3,4-dihydro-
  • 3,4-Dihydro-7-hydroxy-1H-quinolin-2-one
  • 7-Hydroxy-3,4-dihydro-2-quinolinone
  • 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 7-Hydroxy-3,4-dihydrocarbostyril
  • 7-Hydroxy-3,4-dihydroquinoline-2(1H)-one
  • 3,4-Dihydro-7-hydrox
  • 4-dihydro-quinolin-2-one
  • 7-Hydroxy-3
  • 7-HYDROXY-3, 4-DIHYDRO-2(1H)-QUINLIONE
  • Aripiprazole intermediate
  • Aripiprazole EP Impurity A(3,4-Dihydro-7-hydroxyquinoline-2(1H)-one)
  • Aripiprazole Impurity 21（Aripiprazole EP Impurity A）
  • Aripiprazole EP Impurity A
  • 4-Dihydro-7-hydroxy-2(1H)-quinolinone
  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinon
  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone&gt
  • 7-Hydroxy-3,4-dihydro-2(1H)-quinoL
  • 7-HYDROXY-3,4-DIHYDROCARBOSTYRIL 22246-18-0
  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone ISO 9001：2015 REACH
  • Aripiprazole EP Impurity A/ Aripiprazole Dihydroquinolinone Impurity