Description
ChemicalBook > CAS DataBase List > 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

Description
Product Name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
CAS No.
22246-18-0
Chemical Name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Synonyms
7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE;7-HYDROXY-3,4-DIHYDROCARBOSTYRIL;7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE;7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;7-Hydroxy-3;AURORA KA-4813;Aripiprazole Imp.A;3,4-Dihydro-7-hydrox;7-Hydroxy carbostyril;Aripiprazole Impurity 13
CBNumber
CB5325629
Molecular Formula
C9H9NO2
Formula Weight
163.17
MOL File
22246-18-0.mol
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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Property

Melting point:
233-237 °C
Boiling point:
403.7±45.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.60±0.20(Predicted)
color 
Pale Yellow
InChIKey
LKLSFDWYIBUGNT-UHFFFAOYSA-N
CAS DataBase Reference
22246-18-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-43
Safety Statements 
36/37
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
675369
Product name
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
Purity
97%
Packaging
1g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
D3599
Product name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D3599
Product name
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$40
Updated
2024/03/01
Alfa Aesar
Product number
H27485
Product name
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone, 97%
Packaging
1g
Price
$35.9
Updated
2023/06/20
TRC
Product number
D449145
Product name
3,4-Dihydro-7-hydroxyquinoline-2(1H)-one
Packaging
5g
Price
$135
Updated
2021/12/16
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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Chemical Properties,Usage,Production

Description

3,4-Dihydro-7-hydroxy-2 (1H)-quinolinone is a useful organic and pharmaceutical intermediate. It can be used as the precursor of aripiprazole1, which is an antipsychotic medication. It is also an antitumor agent and hydroxyindole analog inhibitor tyrosinase melanoma.

Chemical Properties

Pale Yellow Powder

Uses

3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000).

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Suppliers

Hangzhou Great Forest Biomedical Ltd.
Tel
0571-28313180 17767135330
Fax
0571-28313182
Email
info@great-forest.com
Country
China
ProdList
54
Advantage
58
Beijing Whale Technology Corporation Ltd.
Tel
010-83694934 13671295325
Email
sales@whalecorporation.com
Country
China
ProdList
128
Advantage
58
Nanjing Xinsi Chemical Co., Ltd.
Tel
18805263762
Email
nanjingxinsi@163.com
Country
China
ProdList
434
Advantage
58
Ningbo jinuo chemical co., LTD
Tel
0574-87314919 057487319282
Email
info@nbinno.com
Country
China
ProdList
7027
Advantage
58
Anqing CHICO Pharmaceutical Co., Ltd.
Tel
18061456370 18951649510
Fax
+86-25-52261140
Email
sales@chicopharm.com
Country
China
ProdList
443
Advantage
65
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
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View Lastest Price from 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kgs
Release date
2021-11-16
hebei hongtan Biotechnology Co., Ltd
Product
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14
Hangzhou ICH Biofarm Co., Ltd
Product
7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone 22246-18-0
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99.0%min
Supply Ability
200kg
Release date
2024-10-12

22246-18-0, 3,4-Dihydro-7-hydroxy-2(1H)-quinolinoneRelated Search:


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