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Procaine penicilline G hydrate

Product Name
Procaine penicilline G hydrate
CAS No.
6130-64-9
Chemical Name
Procaine penicilline G hydrate
Synonyms
D02461;mylipen;neoproc;wycillin;afsillin;kabipenin;pen-fifty;cilicaine;flo-cillin;duracillin
CBNumber
CB5334892
Molecular Formula
C29H38N4O6S
Formula Weight
570.71
MOL File
6130-64-9.mol
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Procaine penicilline G hydrate Property

Melting point:
106-110° (with decompn)
Density 
1.255-1.256
storage temp. 
Refrigerator
solubility 
Slightly soluble in water, sparingly soluble in ethanol (96 per cent).
form 
Solid
color 
White to Off-White
CAS DataBase Reference
6130-64-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
42/43
Safety Statements 
36
RTECS 
XH9450000
HS Code 
2941102000
Toxicity
LD50 s.c. in mice: 2.3 g/kg (Soehring)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P3090000
Product name
Procaine benzylpenicillin
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
p3090000
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
1502552
Product name
Penicillin G procaine
Packaging
200mg
Price
$457
Updated
2024/03/01
TRC
Product number
P755200
Product name
ProcainePenicillinGHydrate
Packaging
250mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0099461
Product name
Penicillin G procaine
Purity
98.71%
Packaging
25mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0099461
Product name
Penicillin G procaine
Purity
98.71%
Packaging
100mg
Price
$265
Updated
2021/12/16
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Procaine penicilline G hydrate Chemical Properties,Usage,Production

Description

Benzylpenicillin procaine was developed as a dilatorily acting benzylpenicillin, only slightly soluble in water. It has been used with peanut oil or carboxymethylcellulose as an oil suspension or an aqueous suspension, respectively .

Chemical Properties

White Solid

Uses

Procaine Penicillin G is a composed of the β-lactam antibiotic of Penicillin G and the sodium channel blocker Procaine. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Procaine Penicillin G is used a growth stimulant for poultry.

Uses

Procaine penicilline G hydrate is a composed of the β-lactam antibiotic of Penicillin G and the sodium channel blocker Procaine. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Procaine Penicillin G is used a growth stimulant for poultry.

brand name

Duracillin(Lilly); Pfizerpen (Pfizer).

Antimicrobial activity

The procaine salt of benzylpenicillin. Poorly soluble (1:200 in water). Administered intramuscularly as a suspension of crystals which slowly dissolve at the site of the injection.
It must not be given intravenously. Intramuscular administration produces a flat sustained plasma concentration of penicillin, which is much lower than that achieved by an equivalent dose of benzylpenicillin, with plasma levels still detectable 24 h later. An injection of 0.6 g yields a peak plasma concentration of 1–2 mg benzylpenicillin/L after 2–4 h. Free procaine is detectable in the plasma within 30 min.
Very severe and potentially fatal reactions resembling those of anaphylactic shock, but non-allergic in character, may occur, probably due to accidental entry into the vascular system at the site of injection and blockage of pulmonary and cerebral capillaries by crystals of the suspension. Reactions due to liberated procaine may include acute anxiety, hypertension, tachycardia, vomiting, audiovisual hallucinations and acute psychotic disturbance. The most severe reactions lead to convulsions and cardiac arrest. Other reactions are those to liberated benzylpenicillin.

Procaine penicilline G hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Procaine penicilline G hydrate Suppliers

Austria 1 Canada 1 China 61 Europe 3 Germany 1 India 5 Switzerland 1 United Kingdom 2 United States 14 Global 89
SANDOZ GMBH
Tel
--
Fax
--
Email
kundl.austria@sandoz.com
Country
Austria
ProdList
19
Advantage
58
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View Lastest Price from Procaine penicilline G hydrate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Procaine Penicillin 6130-64-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-03-29
Hebei Mojin Biotechnology Co., Ltd
Product
Procaine penicilline G hydrate 6130-64-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Career Henan Chemical Co
Product
Procaine penicilline G hydrate 6130-64-9
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

6130-64-9, Procaine penicilline G hydrateRelated Search:

ETHANE Dimethyl fumarate Dimethyl carbonate Dimethyl sulfide Dimethyl sulfoxide Dimethyl sebacate Dimethyl ether p-Toluenesulfonic acid monohydrate Benzathine benzylpenicillin Citric acid monohydrate N,N-Dimethylformamide Dimethyl sulfate Procaine Chloral hydrate Penicillin G sodium salt Penicillin G Penicillin G potassium salt Procaine penicillin G Procaine Penicillin

  • abbocillin-dc
  • crysticillin
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  • distaquaine
  • duracillin
  • enylacetamido)-,compd.with2-(diethylamino)ethylp-aminobenzoate(1:1),mono
  • flo-cillin
  • flo-cillinaqueous
  • kabipenin
  • ledercillin
  • mylipen
  • neoproc
  • novocainepenicillin
  • parencillin
  • penaquacaineg
  • pen-fifty
  • penicillingcompd.with2-(diethylamino)ethylp-aminobenzoatehydrate
  • penicillingprocainehydrate
  • premocillin
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  • procainepenicillinghydrate
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  • PENICILLIN G PROCAINE SALT
  • PROCAINE PENICILLIN
  • PENICILLIN-G PROCAIN
  • Procaine penicilline G hydrate
  • 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxilicacid,3,3-dimethyl-7-oxo-6-(2-ph
  • 4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(phenylacetyl)amino- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S-(2alpha,5alpha,6beta))-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate (9CI)
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 2-diethylaminoethyl 4-aminobenzoate hydrate
  • BENXYLPENICILLIN PROCAINE SALT
  • Benzylpenicillin procaine salt, Procaine penicilline G hydrate
  • Penicillin G hydrate procaine salt
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- [2S-(2.alpha.,5.alpha.,6.beta.)]-, compound with 2-(diethylamino)ethyl 4-aminobenzoate (1:1), monohydrate
  • Benzylpenicillin procaine salt
  • D02461
  • Duracillin (tn)
  • Penicillin G procaine (usp)
  • Penicillin G procaine salt hydrate,Benzylpenicillin procaine salt, Procaine penicilline G hydrate
  • Penicillin G Procaine (200 mg)
  • Penicillin G Procaine COS/CGMP
  • Penicillin G procaine salt hydrate
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  • ampin-penicillin
  • aquacillin
  • aquasuspen
  • avloprocil
  • benzylpenicillinicacidprocainesalthydrate
  • benzylpenicillinprocainemonohydrate
  • cilicaine
  • 2-(diethylamino)ethyl 4-aminobenzoate (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
  • Procaine penicilline G hydrate USP/EP/BP
  • Penicillin G procaine (PGP)
  • Penicillin G Procaine (1502552)