ChemicalBook > CAS DataBase List > 4-Chlorobutyronitrile

4-Chlorobutyronitrile

Product Name
4-Chlorobutyronitrile
CAS No.
628-20-6
Chemical Name
4-Chlorobutyronitrile
Synonyms
NSC 8410;orobutyronitriL;4- chloridenitrile;chlorobutyronitrile;4-Chlorbutyronitrile;4-chloro-butyronitril;4-chloro-butanenitril;4-CHLOROBUTANENITRILE;4-CHLOROBUTYRONITRILE;4-Chlorobutyronitryle
CBNumber
CB5336836
Molecular Formula
C4H6ClN
Formula Weight
103.55
MOL File
628-20-6.mol
More
Less

4-Chlorobutyronitrile Property

Boiling point:
195-197 °C (lit.)
Density 
1.095 g/mL at 20 °C
refractive index 
n20/D 1.442(lit.)
Flash point:
185 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Ethyl Acetate (Slightly)
form 
Liquid
Specific Gravity
1.158
color 
Clear colorless to pale yellow
Water Solubility 
immiscible
BRN 
1633582
InChIKey
ZFCFBWSVQWGOJJ-UHFFFAOYSA-N
CAS DataBase Reference
628-20-6(CAS DataBase Reference)
NIST Chemistry Reference
Butanenitrile, 4-chloro-(628-20-6)
EPA Substance Registry System
4-Chlorobutyronitrile (628-20-6)
More
Less

Safety

Hazard Codes 
T,Xi
Risk Statements 
25-36/37/38
Safety Statements 
45-7-36/37/39
RIDADR 
UN 3276 6.1/PG 3
WGK Germany 
3
RTECS 
ET9020000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C30000
Product name
4-Chlorobutyronitrile
Purity
97%
Packaging
100g
Price
$97.2
Updated
2024/03/01
Sigma-Aldrich
Product number
C30000
Product name
4-Chlorobutyronitrile
Purity
97%
Packaging
500g
Price
$293
Updated
2023/06/20
TCI Chemical
Product number
C0925
Product name
4-Chlorobutyronitrile
Purity
>97.0%(GC)
Packaging
25mL
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
C0925
Product name
4-Chlorobutyronitrile
Purity
>97.0%(GC)
Packaging
500mL
Price
$558
Updated
2024/03/01
Alfa Aesar
Product number
A18942
Product name
4-Chlorobutyronitrile, 97%
Packaging
50g
Price
$38.65
Updated
2024/03/01
More
Less

4-Chlorobutyronitrile Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Liquid. 4-Chlorobutyronitrile [628-20-6], 4- chlorobutanenitrile, Cl (CH2 )3CN, Mr 103.55, bp 189 – 191℃ (101.3 kPa), d154 1.0934, n20D 1.4413, is a liquid, miscible with ethanol and diethyl ether; it is immiscible with water.

Uses

4-Chlorobutyronitrile (cas# 628-20-6) is a compound useful in organic synthesis.

Production Methods

4-Chlorobutyronitrile is readily obtained by reacting 1-bromo-3-chloropropane with sodium cyanide. It is used in the synthesis of the pharmaceuticals buflomedil and buspirone. 4-Chlorobutyronitrile also yields cyclopropanecarbonitrile upon cyclization with base.

General Description

A liquid. Flash point 85°F. Density about 9.7 lb / gal and practically insoluble in water (2 parts/100 parts water). Hence sinks in water. Vapors are heavier than air. Irritates the eyes but not to the skin. Releases hydrogen chloride, hydrogen cyanide, and hydrogen bromide gases when heated or involved in a fire.

Air & Water Reactions

Highly flammable. Practically insoluble in water.

Reactivity Profile

4-Chlorobutyronitrile may attack some forms of plastics [USCG, 1999].

Health Hazard

Chemical is moderately toxic. Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Can penetrate the skin on prolonged contact; only slightly irritating.

Fire Hazard

Special Hazards of Combustion Products: Toxic and irritating hydrogen cyanide, hydrogen bromide, and hydrogen chloride may form in fires.

4-Chlorobutyronitrile Preparation Products And Raw materials

Raw materials

1-Bromo-3-chloropropane POTASSIUM CYANIDE

Preparation Products

2-(Thien-2-yl)pyrrolidine 2-(3-BROMO-PROPYL)-1H-BENZOIMIDAZOLE 4-DIMETHYLAMINOBUTYLAMINE 4-Aminobutyric acid 4-(DIETHYLAMINO)BUTYLAMINE Cyclopropanecarboxylic acid
More
Less

4-Chlorobutyronitrile Suppliers

Americas 1 Belgium 3 Canada 2 China 204 Europe 4 France 1 Germany 10 India 15 Japan 5 Slovakia 1 Switzerland 2 The Netherlands 2 Ukraine 2 United Kingdom 13 United States 40 Global 305
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4393
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18086
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2891
Advantage
58
AILY INTL CHEMICAL CORP LTD
Tel
025-83208295 18913388297
Fax
+86-2583208202
Country
China
ProdList
132
Advantage
50
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9900
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2331
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2549
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3989
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3033
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Jinan LuoHe PharmaTech Co., Ltd.
Tel
0531-68658065 15726150375
Fax
0531-68658065
Email
jinanluohe@163.com
Country
China
ProdList
486
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15885
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4773
Advantage
60
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10063
Advantage
53
More
Less

View Lastest Price from 4-Chlorobutyronitrile manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Chlorobutyronitrile 628-20-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Chlorobutyronitrile 628-20-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Chlorobutyronitrile 628-20-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

628-20-6, 4-ChlorobutyronitrileRelated Search:

2,2'-Azobis(2-methylpropionitrile) acrylonitrile-butadiene rubber BUTYRONITRILE Isobutyronitrile Butadiene-acrylonitrile rubber POLY(VINYLIDENE CHLORIDE-CO-ACRYLONITRILE) 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (S)-4-Chloro-3-hydroxybutyronitrile (R)-4-Chloro-3-hydroxybutyronitrile 2,2-DICHLOROCYCLOPROPANE-1-CARBONITRILE CLOFLUBICYNE 2-(2-CHLOROACETYL)-3-(DIMETHYLAMINO)ACRYLONITRILE 2-(1H-BENZIMIDAZOL-2-YL)-4-CHLORO-3-OXOBUTANENITRILE 3-Hydroxy-4-chlorobutyronitrile 2-chlorobutyronitrile 4-Chlorobutyronitrile 4-CHLORO-4-METHYLPENTANENITRILE 2-(2-CHLOROACETYL)-3-(4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]OXY)ANILINO)ACRYLONITRILE

  • GAMMA-CHLOROPROPYL CYANIDE
  • 4-CHLOROBUTYRONITRILE
  • 4-CHLOROBUTANENITRILE
  • 4-chloro-butanenitril
  • 4-chloro-butyronitril
  • Butyronitrile, 4-chloro-
  • gamma-Chlorobutyronitrile
  • 4-CHLOROBUTYRONITRILE 99% (GC)
  • 4-Chlorobutyronitrile 98 %
  • Butanenitrile, 4-chloro-
  • 1-chloro-3-cyanopropane
  • chlorobutyronitrile
  • 4-Chlorobutyronitryle
  • 4-CHLOROBUTYROONITRILE
  • 4-CHLOROBUTYRONITRILE pure
  • g-Chlorobutyronitrile
  • 3-Chloropropyl cyanide
  • 4-Chlorobutyronitrile,97%
  • 4- chloridenitrile
  • 4-Chlorbutyronitrile
  • 4-chlorobutytonitrile
  • 4-Chlorobutyronitrile, 97% 100GR
  • 4-Chloro-1-butyronitrile
  • NSC 8410
  • orobutyronitriL
  • 4-Chlorobutyronitrile &gt
  • best offer 4-Chlorobutyronitrile
  • 628-20-6
  • C5H8NCl
  • ClCH23CN
  • C4H6CIN
  • ClC3H6CN
  • C4H6ClN
  • Organic Building Blocks
  • Nitrogen Compounds
  • Cyanides/Nitriles
  • NITRILE
  • C1 to C5
  • Building Blocks
  • API Intermediate
  • Aliphatics
  • Halogen compounds
  • Miscellaneous
  • C1 to C5
  • Cyanides/Nitriles
  • Nitrogen Compounds