ChemicalBook > CAS DataBase List > 4-Chlorobutyronitrile

4-Chlorobutyronitrile

Product Name
4-Chlorobutyronitrile
CAS No.
628-20-6
Chemical Name
4-Chlorobutyronitrile
Synonyms
NSC 8410;orobutyronitriL;4- chloridenitrile;chlorobutyronitrile;4-Chlorbutyronitrile;4-chloro-butyronitril;4-chloro-butanenitril;4-CHLOROBUTANENITRILE;4-CHLOROBUTYRONITRILE;4-Chlorobutyronitryle
CBNumber
CB5336836
Molecular Formula
C4H6ClN
Formula Weight
103.55
MOL File
628-20-6.mol
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4-Chlorobutyronitrile Property

Boiling point:
195-197 °C (lit.)
Density 
1.095 g/mL at 20 °C
refractive index 
n20/D 1.442(lit.)
Flash point:
185 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Ethyl Acetate (Slightly)
form 
Liquid
Specific Gravity
1.158
color 
Clear colorless to pale yellow
Water Solubility 
immiscible
BRN 
1633582
InChIKey
ZFCFBWSVQWGOJJ-UHFFFAOYSA-N
CAS DataBase Reference
628-20-6(CAS DataBase Reference)
NIST Chemistry Reference
Butanenitrile, 4-chloro-(628-20-6)
EPA Substance Registry System
4-Chlorobutyronitrile (628-20-6)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
25-36/37/38
Safety Statements 
45-7-36/37/39
RIDADR 
UN 3276 6.1/PG 3
WGK Germany 
3
RTECS 
ET9020000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C30000
Product name
4-Chlorobutyronitrile
Purity
97%
Packaging
100g
Price
$97.2
Updated
2024/03/01
Sigma-Aldrich
Product number
C30000
Product name
4-Chlorobutyronitrile
Purity
97%
Packaging
500g
Price
$293
Updated
2023/06/20
TCI Chemical
Product number
C0925
Product name
4-Chlorobutyronitrile
Purity
>97.0%(GC)
Packaging
25mL
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
C0925
Product name
4-Chlorobutyronitrile
Purity
>97.0%(GC)
Packaging
500mL
Price
$558
Updated
2024/03/01
Alfa Aesar
Product number
A18942
Product name
4-Chlorobutyronitrile, 97%
Packaging
50g
Price
$38.65
Updated
2024/03/01
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4-Chlorobutyronitrile Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Liquid. 4-Chlorobutyronitrile [628-20-6], 4- chlorobutanenitrile, Cl (CH2 )3CN, Mr 103.55, bp 189 – 191℃ (101.3 kPa), d154 1.0934, n20D 1.4413, is a liquid, miscible with ethanol and diethyl ether; it is immiscible with water.

Uses

4-Chlorobutyronitrile (cas# 628-20-6) is a compound useful in organic synthesis.

Production Methods

4-Chlorobutyronitrile is readily obtained by reacting 1-bromo-3-chloropropane with sodium cyanide. It is used in the synthesis of the pharmaceuticals buflomedil and buspirone. 4-Chlorobutyronitrile also yields cyclopropanecarbonitrile upon cyclization with base.

General Description

A liquid. Flash point 85°F. Density about 9.7 lb / gal and practically insoluble in water (2 parts/100 parts water). Hence sinks in water. Vapors are heavier than air. Irritates the eyes but not to the skin. Releases hydrogen chloride, hydrogen cyanide, and hydrogen bromide gases when heated or involved in a fire.

Air & Water Reactions

Highly flammable. Practically insoluble in water.

Reactivity Profile

4-Chlorobutyronitrile may attack some forms of plastics [USCG, 1999].

Health Hazard

Chemical is moderately toxic. Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Can penetrate the skin on prolonged contact; only slightly irritating.

Fire Hazard

Special Hazards of Combustion Products: Toxic and irritating hydrogen cyanide, hydrogen bromide, and hydrogen chloride may form in fires.

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4-Chlorobutyronitrile Suppliers

Beckmann-Kenko GmbH
Tel
+49 4241 9308 88
Fax
+49 4241 9308 89
Email
info@beckmann-kenko.com
Country
Germany
ProdList
478
Advantage
62
Aaron Chemistry GmbH
Tel
--
Fax
--
Email
sales@aaron-chemistry.de
Country
Germany
ProdList
579
Advantage
60
Merck Millipore
Tel
--
Fax
--
Email
ccc@merckgroup.com
Country
Germany
ProdList
2008
Advantage
58
BIESTERFELD SPEZIALCHEMIE GMBH
Tel
--
Fax
--
Email
compliance@biesterfeld.com
Country
Germany
ProdList
211
Advantage
58
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
EMKA-Chemie Organische Feinchemikalien
Tel
--
Fax
--
Country
Germany
ProdList
661
Advantage
30
Merck Schuchardt OHG
Tel
--
Fax
--
Email
schuchardt-vertrieb@merck.de
Country
Germany
ProdList
5827
Advantage
74
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View Lastest Price from 4-Chlorobutyronitrile manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Chlorobutyronitrile 628-20-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Chlorobutyronitrile 628-20-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Chlorobutyronitrile 628-20-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

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