ML335

Product Name: ML335
CAS No.: 825658-06-8
Chemical Name: ML335
Synonyms: TREK-1/2 Activator;ML335; ML-335; ML 335; TREK-1/2 ACTIVATOR;N-(2,4-Dichlorobenzyl)-4-(methylsulfonamido)benzamide;Potassium Channel,ML-335,ML 335,ML335,KcsA,Inhibitor,inhibit;Benzamide, N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-
CBNumber: CB53373069
Molecular Formula: C15H14Cl2N2O3S
Formula Weight: 373.25
MOL File: 825658-06-8.mol

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ML335 Property

storage temp.: -20°
solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml with warming).
form: solid
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27635
Product name: ML335
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 27635
Product name: ML335
Packaging: 10mg
Price: $115
Updated: 2024/03/01

Cayman Chemical

Product number: 27635
Product name: ML335
Packaging: 25mg
Price: $254
Updated: 2024/03/01

Cayman Chemical

Product number: 27635
Product name: ML335
Packaging: 50mg
Price: $477
Updated: 2024/03/01

TRC

Product number: M425225
Product name: ML335
Packaging: 5mg
Price: $185
Updated: 2021/12/16

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ML335 Chemical Properties,Usage,Production

Description

Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses to anesthetics. ML-335 (825658-06-8) is a novel, selective TREK-1,2 activator with EC50s of 14.3 and 5.2 μM.1?It represents an important new pharmacological tool for studying the physiology of TREK channels.

Uses

ML335, is a selective activator of both TREK-1 and TREK-2.

storage

Store at +4°C

References

1) Lolicato?et al.?(2017),?K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site; Nature,?547?364

ML335 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML335 Suppliers

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825658-06-8, ML335Related Search:

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ML335; ML-335; ML 335; TREK-1/2 ACTIVATOR

TREK-1/2 Activator

Benzamide, N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-

Potassium Channel,ML-335,ML 335,ML335,KcsA,Inhibitor,inhibit

N-(2,4-Dichlorobenzyl)-4-(methylsulfonamido)benzamide

825658-06-8