Cyclophosphamide monohydrate
- Product Name
- Cyclophosphamide monohydrate
- CAS No.
- 6055-19-2
- Chemical Name
- Cyclophosphamide monohydrate
- Synonyms
- CPA;Cyclophosphamide sterile;CYTOXAN;ENDOXON;Procy-tox;Cycloblastin;-2monohydrate;endoxanmonohydrate;TIMTEC-BB SBB003026;cyclophosphamide，CTX
- CBNumber
- CB5345867
- Molecular Formula
- C7H17Cl2N2O3P
- Formula Weight
- 279.1
- MOL File
- 6055-19-2.mol
Cyclophosphamide monohydrate Property
- Melting point:
- 49-51 °C (lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- H2O: 0.1 g/mL, clear, colorless
- form
- Crystals or Crystalline Powder
- color
- White to almost white
- Water Solubility
- 40 g/L
- Merck
- 14,2747
- BRN
- 8167897
- Stability:
- Hygroscopic
- InChIKey
- PWOQRKCAHTVFLB-UHFFFAOYSA-N
- CAS DataBase Reference
- 6055-19-2(CAS DataBase Reference)
- IARC
- 1 (Vol. 26, Sup 7, 100A) 2012
- EPA Substance Registry System
- Cyclophosphamide monohydrate (6055-19-2)
Safety
- Hazard Codes
- T
- Risk Statements
- 45-25-61-46-36/37/38-23/24/25
- Safety Statements
- 53-45-37/39-26
- RIDADR
- UN 3464 6.1/PG 3
- WGK Germany
- 3
- RTECS
- RP6157750
- F
- 10
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H340May cause genetic defects
H350May cause cancer
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 93813
- Product name
- Cyclophosphamide monohydrate
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $69.5
- Updated
- 2024/03/01
- Product number
- 239785
- Product name
- CyclophosphamideMonohydrate-CAS6055-19-2-Calbiochem
- Purity
- Awidelyusedanti-neoplasticagentthatalsodisplaysimmunosuppressantpropert
- Packaging
- 1g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- C2236
- Product name
- Cyclophosphamide Monohydrate
- Purity
- >98.0%(N)
- Packaging
- 5g
- Price
- $114
- Updated
- 2024/03/01
- Product number
- C2236
- Product name
- Cyclophosphamide Monohydrate
- Purity
- >98.0%(N)
- Packaging
- 25g
- Price
- $385
- Updated
- 2024/03/01
- Product number
- 13849
- Product name
- Cyclophosphamide (hydrate)
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $32
- Updated
- 2024/03/01
Cyclophosphamide monohydrate Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Uses
It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
Uses
antineoplastic, alkylating agent
Uses
An immunosuppressive, cytotoxic apoptosis inducer.
Uses
Cyclophosphamide monohydrate is used to treat cancers, autoimmune disorders and AL amyloidosis. It is a nitrogen mustard alkylating agent and reacts with deoxyribonucleic acid (DNA) to get its alkylated derivative. It is also involved in cancer research as a tool that induces apoptosis in tumor cells.
Uses
alkylating agent in cancer therapy
Definition
ChEBI: The monohydrate of cyclophosphamide.
brand name
Cytoxan (Bristol-Myers Squibb); Neosar (Sicor).
General Description
Fine white crystalline powder with a slightly bitter taste. Little or no odor.
Air & Water Reactions
Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions.
Reactivity Profile
Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis.
Fire Hazard
Cyclophosphamide monohydrate is probably combustible.
Biochem/physiol Actions
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Safety Profile
Confirmed human carcinogen. Poison by ingestion and intravenous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, PO,, and NOx.
Cyclophosphamide monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclophosphamide monohydrate Suppliers
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View Lastest Price from Cyclophosphamide monohydrate manufacturers
- Product
- Cyclophosphamide monohydrate 6055-19-2
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-07
- Product
- Cyclophosphamide monohydrate 6055-19-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 97%-103%; USP
- Supply Ability
- 500kgs
- Release date
- 2021-07-14
- Product
- Cyclophosphamide Monohydrate 6055-19-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 50kg/Month
- Release date
- 2024-09-05