Tetraethylene glycol dimethyl ether Property

Melting point:

-30 °C (lit.)

Boiling point:

275-276 °C (lit.)

Density 

1.009 g/mL at 25 °C (lit.)

vapor density 

7.7 (vs air)

vapor pressure 

<0.01 mm Hg ( 20 °C)

refractive index 

n20/D 1.432(lit.)

Flash point:

285 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Liquid

color 

Clear

Specific Gravity

1.01

explosive limit

0.8%(V)

Water Solubility 

Soluble

Merck 

14,9208

BRN 

1760005

InChIKey

ZUHZGEOKBKGPSW-UHFFFAOYSA-N

LogP

-0.84 at 23℃

CAS DataBase Reference

143-24-8(CAS DataBase Reference)

NIST Chemistry Reference

CH3O[CH2CH2O]4CH3(143-24-8)

EPA Substance Registry System

Tetraglyme (143-24-8)

Safety

Hazard Codes 

Xi

Risk Statements 

19-43-62-61

Safety Statements 

36-24-45-36/37-53-26

WGK Germany 

1

RTECS 

SB0400000

Autoignition Temperature

510 °F

TSCA 

Yes

HS Code 

2909 19 90

Toxicity

LD50 orally in rats: 5.14 g/kg (Smyth)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

Tetraethylene glycol dimethyl ether Chemical Properties,Usage,Production

Chemical Properties

clear liquid

Uses

Tetraethylene glycol dimethyl ether is used in lithium-ion battery technology. It is associated with trifluoroethanol and used as a working pair for organic absorption heat pumps. It acts as a solvent for cleaning and degreasing due to its chemical and thermal stability. Moreover, it is suitable solvent for high temperature reactions due its high boiling point. Further, it is used in the selective adsorption of proteins during the promotion of cell adhesion.

Uses

Tetraethylene glycol dimethyl ether is used as a solvent.

Definition

ChEBI: Tetraglyme is a polyether.

General Description

Tetraethylene glycol dimethyl ether or tetraglyme is an organic aprotic colourless solvent with film forming ability.

Flammability and Explosibility

Non flammable

Safety Profile

Mildly toxic by ingestion. Experimental reproductive effects. An eye irritant. Many glycol ethers are suspected of having dangerous human reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS

Purification Methods

Stand the ether over CaH2, LiAlH4 or sodium, and distil it when required. [Beilstein 1 IV 2404.]

Advantages

Tetraethylene glycol dimethyl ether (TEGDME) could be used as a bifunctional solvent which serves as both the casting solvent and active component by controlling the residual amount of TEGDME from excessive to appropriate. This method could avoid the negative impact of the residual organic solvent (such as acetonitrile) in polymer electrolytes prepared by the solution-casting method on battery performance. The residual TEGDME serves as a plasticizer in HSE that is beneficial for improving the plasticity and decreasing the crystallinity of PEO so that it can increase the mobility of lithium ions and flexibility of solid electrolytes. TEGDME can also improve the plasticity and interfacial contact[1].

Environmental considerations

Tetraethylene glycol dimethyl ether is a polar, non-aromatic compound. It is nonionic but water-soluble due to its polarity. However, it has been detected in municipal effluents, runoff from fields irrigated with treated wastewater, and wastewaters of two different waste oil refineries Citation[2].

References

[1] Hao-Ran Wang, &nbsp;Ya-Nan Yang and &nbsp; Tao Zhang*. “Tape-Casting Method of Hybrid Solid Electrolytes with a Residual Active Solvent of Tetraethylene Glycol Dimethyl Ether.” ACS Applied Energy Materials 6 3 (2023): 2031–2038.
[2] Holger Gulyas. “Combining activated carbon adsorption with heterogeneous photocatalytic oxidation: lack of synergy for biologically treated greywater and tetraethylene glycol dimethyl ether.” Environmental Technology 34 9–12 (2013): 1393–403.