Description References
ChemicalBook > CAS DataBase List > Ethyl Hexanoate

Ethyl Hexanoate

Description References
Product Name
Ethyl Hexanoate
CAS No.
123-66-0
Chemical Name
Ethyl Hexanoate
Synonyms
ETHYL CAPROATE;HEXANOIC ACID ETHYL ESTER;2-ETHYLHEXANOATE;Ethyl butyl acetate;Ethyl hexyl;ETHYL N-CAPROATE;ETHYL N-HEXANOATE;FEMA 2439;ETHYL HEXOATE;ETHYLCAPRONAT
CBNumber
CB5350375
Molecular Formula
C8H16O2
Formula Weight
144.21
MOL File
123-66-0.mol
More
Less

Ethyl Hexanoate Property

Melting point:
-67°C
Boiling point:
168 °C (lit.)
Density 
0.869 g/mL at 25 °C (lit.)
vapor density 
5 (vs air)
vapor pressure 
4hPa at 25℃
FEMA 
2439 | ETHYL HEXANOATE
refractive index 
n20/D 1.407
Flash point:
121 °F
storage temp. 
Flammables area
solubility 
0.63g/l
form 
Liquid
color 
Clear colorless
Odor
at 1.00 % in dipropylene glycol. sweet fruity pineapple waxy green banana
Odor Type
fruity
explosive limit
0.9%(V)
Water Solubility 
INSOLUBLE
Merck 
14,3777
JECFA Number
31
BRN 
1701293
Dielectric constant
4.5700000000000003
InChIKey
SHZIWNPUGXLXDT-UHFFFAOYSA-N
LogP
2.96 at 22.4℃
CAS DataBase Reference
123-66-0(CAS DataBase Reference)
NIST Chemistry Reference
Hexanoic acid, ethyl ester(123-66-0)
EPA Substance Registry System
Ethyl hexanoate (123-66-0)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37/38-R36/37/38-R10
Safety Statements 
16-26-36-S36-S26-S16
RIDADR 
UN 3272 3/PG 3
WGK Germany 
1
RTECS 
MO7735000
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29159000
Toxicity
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Moreno, 1975).
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P370+P378In case of fire: Use … for extinction.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W243914
Product name
Ethyl Hexanoate
Purity
natural, ≥98%, FCC, FG
Packaging
1kg
Price
$123
Updated
2024/03/01
Sigma-Aldrich
Product number
W243914
Product name
Ethyl Hexanoate
Purity
natural, ≥98%, FCC, FG
Packaging
4kg
Price
$355
Updated
2024/03/01
Sigma-Aldrich
Product number
W243914
Product name
Ethyl Hexanoate
Purity
natural, ≥98%, FCC, FG
Packaging
9kg
Price
$507
Updated
2024/03/01
Sigma-Aldrich
Product number
W243906
Product name
Ethyl Hexanoate
Purity
≥98%, FCC, FG
Packaging
1kg
Price
$73.2
Updated
2024/03/01
Sigma-Aldrich
Product number
W243906
Product name
Ethyl Hexanoate
Purity
≥98%, FCC, FG
Packaging
4kg
Price
$170
Updated
2024/03/01
More
Less

Ethyl Hexanoate Chemical Properties,Usage,Production

Description

Ethyl caproate (also ethyl hexanoate) is naturally found in the fruits of Ananas sativus. It can be synthesized by the direct esterification of caproic acid with ethyl alcohol. It has strong, sweet-ethereal like pineapple odor, with nuances of banana and strawberry.
Ethyl caproate is approved by the FDA for food use (as a flavoring agent in desserts and beverages) without hazard to public health. Ethyl Caproate is used to synthesize novel EP2/EP4 dual agonist of γ-lactam prostaglandin E1 analogs. It is also used as a chemical reagent in the synthesis of PPARα antagonists in the treatment of metabolic diseases.

References

[1] D. L. J. Opdyke (1974) Monographs on Fragrance Raw Materials
[2] https://www.trc-canada.com

Chemical Properties

Ethyl Hexanoate is a colorless liquid with a strong fruity odor, reminiscent of pineapples. It occurs in many fruits and is used in small amounts for floral, fruity notes in perfume compositions and in larger quantities in fruit flavors.

Chemical Properties

Ethyl hexanoate has a powerful, fruity odor with a pineapple–banana note. It has been also reported to have a winy odor.

Chemical Properties

CLEAR COLOURLESS LIQUID

Occurrence

Reported found in strawberry, rum, bourbon, cocoa, kiwi fruit, black currant, apple, orange and grapefruit juice, guava, Vitis vinifera, pineapple, strawberry jam, clove bud, cheeses, cognac, whiskies, grape wines, passion fruit juice, mango, fruit brandies, figs, corn oil, mountain papaya, pawpaw and mastic gum leaf oil.

Uses

Ethyl Caproate is used in the synthesis of novel EP2/EP4 dual agonist of γ-lactam prostaglandin E1 analogs. Also used as a chemical reagent in the synthesis of PPARα antagonists in the treatment of metabolic diseases.

Uses

Ethyl hexanoate may be used as an analytical reference standard for the determination of the analyte in wine and beer samples by chromatography based techniques.

Uses

manufacture of artificial fruit flavors.

Definition

ChEBI: A fatty acid ethyl ester obtained by the formal condensation of hexanoic acid with ethanol.

Preparation

By esterification of caproic acid with ethyl alcohol in the presence of concentrated H2SO4 or HCl

Aroma threshold values

Detection: 0.3 to 5 ppb

Taste threshold values

Taste characteristics at 10 ppm: fruity and waxy with a tropical nuance.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 818, 1968 DOI: 10.1021/ja01005a064
Synthetic Communications, 14, p. 77, 1984 DOI: 10.1080/00397918408060867
Synthesis, p. 929, 1978 DOI: 10.1055/s-1978-24945

General Description

Ethyl hexanoate is one of the odorants contributing to the typical guava aroma. It also contributes to the fresh strawberry aroma.

Safety Profile

A skin irritant. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. When heated to decomposition it emits acrid smoke and irritating fumes. To fight fire, use CO2, foam, dry chemical. See also ESTERS.

Carcinogenicity

Not listed by ACGIH, California Proposition 65, IARC, NTP, or OSHA.

Metabolism

Aliphatic esters, including ethyl caproate, are thought to be readily hydrolysed to the corresponding alcohol and acid, which are then further metabolized (Fassett, 1963). Ethyl caproate administered orally to rats produced a uniform ketonuria and it was considered probable that caproic acid was broken down chiefly by ?-oxidation (Deuel, Hallman, Butts & Murray, 1936). When 2 g ethyl caproate dissolved in aqueous ethanol was fed directly into the rumen of a cow, 0.003°/ was transferred to the milk, reaching a maximum level of 60 /fg/litre after 2-4 hr (Honkanen, Karvonen & Virtanen, 1964). The energy from ethyl caproate was 52% available when the ester was fed to four chicks at a level of 5% in the diet (Yoshida et al. 1970).

Solubility in organics

Soluble in oils and alcohol. Poorly soluble in Ropylene glycol, insoluble in Glycerin.

Ethyl Hexanoate Preparation Products And Raw materials

Raw materials

Ethanol Hexanoic acid Calcium chloride Anthraquinone Sodium carbonate

Preparation Products

ethyl 4,6,6,6-tetrachloro-3,3-dimethylhexanoate cis-DL-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
More
Less

Ethyl Hexanoate Suppliers

Americas 1 Australia 2 Belgium 1 China 244 Czech 1 Europe 6 France 3 Germany 13 India 25 Ireland 1 Italy 1 Japan 7 Mexico 1 Singapore 1 Slovakia 1 South Africa 1 South Korea 2 Spain 3 Switzerland 3 United Kingdom 12 United States 78 Global 407
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Fleurchem Inc.,
Tel
--
Fax
--
Country
United States
ProdList
119
Advantage
58
PearlChem Corporation
Tel
--
Fax
--
Email
info@pearlchemcorp.com
Country
United States
ProdList
131
Advantage
58
Riverside Aromatics Ltd.
Tel
--
Fax
--
Email
info@riversidearomatics.com
Country
United States
ProdList
275
Advantage
58
Ungerer & Company
Tel
--
Fax
--
Email
cowens@UngererAndCompany.com
Country
United States
ProdList
79
Advantage
58
Auro Chemicals
Tel
--
Fax
--
Email
customerservice@aurochemicals.com
Country
United States
ProdList
246
Advantage
58
H.Interdonati inc.
Tel
--
Fax
--
Email
flavorplus@aol.com
Country
United States
ProdList
105
Advantage
58
Nice Group Inc
Tel
--
Fax
--
Email
Amy@nicegroupinc.com
Country
United States
ProdList
134
Advantage
58
Frutarom (F&F Ingredients)
Tel
--
Fax
--
Email
info@frutarom.com
Country
United States
ProdList
280
Advantage
58
Citrus and Allied Essences Ltd.
Tel
--
Fax
--
Email
galloca@citrusandallied.com
Country
United States
ProdList
90
Advantage
58
Advanced Biotech - ABT
Tel
--
Fax
--
Country
United States
ProdList
260
Advantage
58
Bell Flavors & Fragrances Inc.
Tel
--
Fax
--
Email
tlauren@bellff.com
Country
United States
ProdList
29
Advantage
58
Prodasynth
Tel
--
Fax
--
Email
info@prodasynth.com
Country
United States
ProdList
423
Advantage
58
Lluch Essence S.L.
Tel
--
Fax
--
Email
web@lluche.com
Country
United States
ProdList
2352
Advantage
58
Taytonn ASCC Pte Ltd
Tel
--
Fax
--
Email
info@taytonnascc.com
Country
United States
ProdList
742
Advantage
58
Augustus Oils Ltd
Tel
--
Fax
--
Email
essentials@augustus-oils.ltd.uk
Country
United States
ProdList
1404
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
Vigon International, Inc.
Tel
--
Fax
--
Email
jpassamonte@vigoninternational.com
Country
United States
ProdList
1268
Advantage
64
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Sunaux International
Tel
--
Fax
--
Email
johnjft@sunaux.com
Country
United States
ProdList
581
Advantage
58
Robertet, Inc.
Tel
--
Fax
--
Email
info@robertetUSA.com
Country
United States
ProdList
1026
Advantage
58
Excellentia International
Tel
--
Fax
--
Email
info@excellentiaint.com
Country
United States
ProdList
567
Advantage
58
Elan Inc.
Tel
--
Fax
--
Email
dpimentel@elan-chemical.com
Country
United States
ProdList
116
Advantage
58
Qingdao Free Trade Zone United International Co Ltd
Tel
--
Fax
--
Email
info@unitedint.com
Country
United States
ProdList
604
Advantage
58
Indukern, S.A. F&F Ingredients Division
Tel
--
Fax
--
Email
info@indukern.es
Country
United States
ProdList
1321
Advantage
58
Advanced Biotech. Inc.
Tel
--
Fax
--
Email
info@adv-bio.com
Country
United States
ProdList
1121
Advantage
58
SILVERLINE CHEMICALS
Tel
--
Fax
--
Email
silverlinechemical1@gmail.com
Country
United States
ProdList
138
Advantage
47
Fleurchem, Inc.
Tel
--
Fax
--
Email
info@fleurchem.com
Country
United States
ProdList
790
Advantage
58
Vigon International
Tel
--
Fax
--
Email
sales@vigon.com
Country
United States
ProdList
1776
Advantage
58
ECSA Chemicals
Tel
--
Fax
--
Email
marketing@ecsa.ch
Country
United States
ProdList
1735
Advantage
58
Odowell Co.,ltd
Tel
--
Fax
--
Email
info@odowell.com
Country
United States
ProdList
62
Advantage
58
Pyrazine Specialties, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1265
Advantage
30
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
FRUTAROM USA INC,
Tel
--
Fax
--
Email
Sales.IFFIngredients@iff.com
Country
United States
ProdList
500
Advantage
58
M&U International LLC
Tel
--
Fax
--
Email
sales@mu-intel.com
Country
United States
ProdList
2011
Advantage
58
R C Treatt and Co Ltd
Tel
--
Fax
--
Email
enquiries@treatt.com
Country
United States
ProdList
1690
Advantage
58
Alfrebro LLC/ Archer Daniels Midland Company
Tel
--
Fax
--
Email
sforbis@alfrebro.com
Country
United States
ProdList
768
Advantage
58
Moellhausen S.P.A.
Tel
--
Fax
--
Country
United States
ProdList
1676
Advantage
58
H. Interdonati, Inc.
Tel
--
Fax
--
Email
flavorplus@hinterdonati.com
Country
United States
ProdList
261
Advantage
58
The John D. Walsh Company, Inc
Tel
--
Fax
--
Email
info@johndwalsh.com
Country
United States
ProdList
1139
Advantage
58
The Lermond Company
Tel
--
Fax
--
Email
info@lermond.com
Country
United States
ProdList
763
Advantage
58
Berje Inc.
Tel
--
Fax
--
Email
tlauzurica@berjeinc.com
Country
United States
ProdList
958
Advantage
58
SRS Aromatics Ltd
Tel
--
Fax
--
Email
info@srsaromatics.co.uk
Country
United States
ProdList
2315
Advantage
46
Global Essence Inc.
Tel
--
Fax
--
Email
info@globalessenceuk.com
Country
United States
ProdList
758
Advantage
58
Ernesto Ventós S.A.
Tel
--
Fax
--
Email
info@ventos.com
Country
United States
ProdList
2257
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
More
Less

View Lastest Price from Ethyl Hexanoate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl Hexanoate 123-66-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-22
Hebei Chuanghai Biotechnology Co,.LTD
Product
Ethyl Hexanoate 123-66-0
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Hebei Kingfiner Technology Development Co.Ltd
Product
Ethyl Hexanoate 123-66-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000
Release date
2023-12-25

123-66-0, Ethyl HexanoateRelated Search:

Tris(trimethylsilyl)phosphate 2-Ethoxyethanol Dimethyl succinate Cholesteryl hexanoate Allyl hexanoate Ethanol Ethyl acetate Ethyl formate Ethyl propionate Hexanoic acid Trinexapac-ethyl ISOXADIFEN-ETHYL 6-Aminocaproic acid Ethylparaben N-HEXADECYLPHOSPHONIC ACID DIETHYL SEC-BUTYLMALONATE N-DODECYLPHOSPHONIC ACID Hexane Ethyl Caproate

  • Ethyl hexanoate >=99%
  • Ethyl hexyl
  • Acetic acid, butyl-, ethyl ester
  • Ethyl butyl acetate
  • Ethyl ester of hexanoic acid
  • Ethylcapronate
  • CAPROIC ACID ETHYL ESTER
  • CAPRONIC ETHER
  • FEMA 2439
  • ETHYL CAPROATE
  • ETHYL N-CAPROATE
  • ETHYL N-HEXANOATE
  • ETHYL HEXANOATE
  • ETHYL HEXOATE
  • HEXANOIC ACID ETHYL ESTER
  • RARECHEM AL BI 0164
  • N-CAPROIC ACID ETHYL ESTER
  • ethyl caproate (ethyl hexanoate)
  • Ethyl haxanoate
  • ETHYL HEXANOATE 98+% NATURAL FCC
  • ETHYL CAPROATE (ETHYL HEXANOATE), 99+%
  • ETHYL HEXANOATE 98+% FCC
  • ETHYL HEXANOATE GC STANDARD
  • Ethyl caproate, 99+%
  • CAPROIC ACID ETHYLESTER(SG)
  • Ethylhrxanoate
  • α-ethylcarpotic acid
  • 2-ETHYLHEXANOATE
  • ETHYLCAPRONAT
  • Ethylhexanoat
  • Caproic acid ethyl
  • esterHexanoic acid,ethyl ester
  • CAPROIC ACID ETHYLESTER WITH GC
  • ETHYL CAPROATE NATURAL
  • Caproic acid ethyl ester, Ethyl caproate
  • Hexanoic acid ethyl
  • 2-Ethylhexanoic acidanion
  • Ethyl hexanoate,Caproic acid ethyl ester, Ethyl caproate
  • ethyl caproate ,ethyl hexoate。
  • Ethyl n-hexoate
  • Ethyl caproate >=99.0%
  • Ethyl caproate, 99+% 500ML
  • Ethyl caproate, 99+% 5ML
  • Ethyl Caproate Hexanoic Acid Ethyl Ester
  • ETHYL HEXANOATE FOR SYNTHESIS
  • Ehyl caproate
  • Natural Ethyl Caproate
  • Ethyl Hexanoate(C6:0)
  • Natural Ethyl Hexanoate
  • EthylHexanoate&gt
  • Ethyl Hexanoate USP/EP/BP
  • Ethyl hexanoate(kosher)
  • High purity CAS 123-66-0 Ethyl Hexanoate in stock
  • thyl hexanoate
  • HEXANOIC ETHYL
  • Ethyl caproate(C6:0)
  • Ethyl hexanoate in isooctane
  • Hexanoic acid ethyl ester in Acetonitrile