ChemicalBook > CAS DataBase List > 2,6-Difluorobenzamide

2,6-Difluorobenzamide

Product Name
2,6-Difluorobenzamide
CAS No.
18063-03-1
Chemical Name
2,6-Difluorobenzamide
Synonyms
2,6-difluorobenzoic acid amide;uorobenzamide;2,6-Difluorbenzamid;2,6-DIFLUOROBENZAMIDE;2,6-difluoro-benzamid;2,6-difluorobenzaminde;2,6-Difluorobenzoamide;2,6-Difluorobenzoylamide;2,6-Difluorobenzamide97%;2,6-Difluorobenzamide>
CBNumber
CB5376515
Molecular Formula
C7H5F2NO
Formula Weight
157.12
MOL File
18063-03-1.mol
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2,6-Difluorobenzamide Property

Melting point:
145-148 °C (lit.)
Boiling point:
51-52C/15Tor
Density 
1,199g/cm
refractive index 
1,508
storage temp. 
Sealed in dry,Room Temperature
solubility 
ethanol: soluble5%, clear to turbid, colorless to light yellow
pka
14.54±0.50(Predicted)
form 
Solid
color 
Off-White
BRN 
2047480
InChIKey
AVRQBXVUUXHRMY-UHFFFAOYSA-N
LogP
0.011-0.25 at 25℃
CAS DataBase Reference
18063-03-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzamide, 2,6-difluoro-(18063-03-1)
EPA Substance Registry System
Benzamide, 2,6-difluoro- (18063-03-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20
Safety Statements 
26-37/39-36/37
WGK Germany 
1
RTECS 
CV4355050
HazardClass 
IRRITANT
HS Code 
29242990
Toxicity
rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
282278
Product name
2,6-Difluorobenzamide
Purity
97%
Packaging
10g
Price
$22.62
Updated
2024/03/01
Sigma-Aldrich
Product number
282278
Product name
2,6-Difluorobenzamide
Purity
97%
Packaging
50g
Price
$41.2
Updated
2024/03/01
TCI Chemical
Product number
D1907
Product name
2,6-Difluorobenzamide
Purity
>97.0%(N)
Packaging
25g
Price
$30
Updated
2024/03/01
Alfa Aesar
Product number
A11685
Product name
2,6-Difluorobenzamide, 98+%
Packaging
25g
Price
$53
Updated
2023/06/20
Alfa Aesar
Product number
A11685
Product name
2,6-Difluorobenzamide, 98+%
Packaging
100g
Price
$139
Updated
2021/12/16
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2,6-Difluorobenzamide Chemical Properties,Usage,Production

Description

2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.

Description

2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].

Chemical Properties

white to yellowish powder

Uses

2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.

Preparation

2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.

References

[1] Straniero V, et al. 2,6-Difluorobenzamide inhibitors of the bacterial cell division protein FtsZ: design, synthesis and Structure Activity Relationship study. ChemMedChem, 2017; 12: 1303-1318.

2,6-Difluorobenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,6-Difluorobenzamide manufacturers

Anhui Royal Chemical Co., Ltd.
Product
2,6-Difluorobenzamide 18063-03-1
Price
US $1.00/KG
Min. Order
200KG
Purity
99%
Supply Ability
20ton
Release date
2018-08-08
Henan Fengda Chemical Co., Ltd
Product
2,6-Difluorobenzamide 18063-03-1
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Hebei Yanxi Chemical Co., Ltd.
Product
2,6-Difluorobenzamide 18063-03-1
Price
US $40.00-40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-26

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