2,6-Difluorobenzamide

ChemicalBook > CAS DataBase List > 2,6-Difluorobenzamide

2,6-Difluorobenzamide

Product Name: 2,6-Difluorobenzamide
CAS No.: 18063-03-1
Chemical Name: 2,6-Difluorobenzamide
Synonyms: 2,6-difluorobenzoic acid amide;uorobenzamide;2,6-Difluorbenzamid;2,6-DIFLUOROBENZAMIDE;2,6-difluoro-benzamid;2，6-difluorobenzaminde;2,6-Difluorobenzoamide;2,6-Difluorobenzoylamide;2,6-Difluorobenzamide97%;2,6-Difluorobenzamide>
CBNumber: CB5376515
Molecular Formula: C7H5F2NO
Formula Weight: 157.12
MOL File: 18063-03-1.mol

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2,6-Difluorobenzamide Property

Melting point:: 145-148 °C (lit.)
Boiling point:: 51-52C/15Tor
Density: 1,199g/cm
refractive index: 1,508
storage temp.: Sealed in dry,Room Temperature
solubility: ethanol: soluble5%, clear to turbid, colorless to light yellow
pka: 14.54±0.50(Predicted)
form: Solid
color: Off-White
BRN: 2047480
InChIKey: AVRQBXVUUXHRMY-UHFFFAOYSA-N
LogP: 0.011-0.25 at 25℃
CAS DataBase Reference: 18063-03-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzamide, 2,6-difluoro-(18063-03-1)
EPA Substance Registry System: Benzamide, 2,6-difluoro- (18063-03-1)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20
Safety Statements: 26-37/39-36/37
WGK Germany: 1
RTECS: CV4355050
HazardClass: IRRITANT
HS Code: 29242990
Toxicity: rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 282278
Product name: 2,6-Difluorobenzamide
Purity: 97%
Packaging: 10g
Price: $22.62
Updated: 2024/03/01

Sigma-Aldrich

Product number: 282278
Product name: 2,6-Difluorobenzamide
Purity: 97%
Packaging: 50g
Price: $41.2
Updated: 2024/03/01

TCI Chemical

Product number: D1907
Product name: 2,6-Difluorobenzamide
Purity: >97.0%(N)
Packaging: 25g
Price: $30
Updated: 2024/03/01

Alfa Aesar

Product number: A11685
Product name: 2,6-Difluorobenzamide, 98+%
Packaging: 25g
Price: $53
Updated: 2023/06/20

Alfa Aesar

Product number: A11685
Product name: 2,6-Difluorobenzamide, 98+%
Packaging: 100g
Price: $139
Updated: 2021/12/16

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2,6-Difluorobenzamide Chemical Properties,Usage,Production

Description

2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.

Description

2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].

Chemical Properties

white to yellowish powder

Uses

2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.

Preparation

2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.

References

[1] Straniero V, et al. 2,6-Difluorobenzamide inhibitors of the bacterial cell division protein FtsZ: design, synthesis and Structure Activity Relationship study. ChemMedChem, 2017; 12: 1303-1318.

2,6-Difluorobenzamide Preparation Products And Raw materials

Raw materials

Potassium fluoride 2,6-Difluorobenzonitrile

Preparation Products

Flufenoxuron Hexaflumuron 2,6-Difluoroaniline 2,6-Difluorobenzoyl isocyanate Chlorfluazuron Diflubenzuron Teflubenzuron

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View Lastest Price from 2,6-Difluorobenzamide manufacturers

Anhui Royal Chemical Co., Ltd.

Product: 2,6-Difluorobenzamide 18063-03-1
Price: US $1.00/KG
Min. Order: 200KG
Purity: 99%
Supply Ability: 20ton
Release date: 2018-08-08

Henan Fengda Chemical Co., Ltd

Product: 2,6-Difluorobenzamide 18063-03-1
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-22

Hebei Yanxi Chemical Co., Ltd.

Product: 2,6-Difluorobenzamide 18063-03-1
Price: US $40.00-40.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-09-26

18063-03-1, 2,6-DifluorobenzamideRelated Search:

2,6-Difluorobenzoic acid Chlorantraniliprole p-Aminobenzamide 2,6-Difluorobenzonitrile Benzamide Difluorochloromethane 2,3,6-TRIFLUOROBENZAMIDE 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE Diflubenzuron Chlorfluazuron 2,6-Difluorobenzoyl hydrazine Teflubenzuron N-PENTAFLUOROBENZOYLIMIDAZOLE 2,3,4,5,6-PENTAFLUOROBENZAMIDE 3,5-DIFLUOROBENZAMIDE 2-CHLORO-3,6-DIFLUOROBENZAMIDE 3-CHLORO-2,6-DIFLUOROBENZAMIDE 2,5-DIFLUOROBENZAMIDE

2,6-difluorobenzoic acid amide

2,6-Difluorobenzamide97%

2,6-Difluorbenzamid

2,6-Difluorobenzoylamide

2,6-DIFLUOROBENZAMIDE, 98+%

2,6-Difluorobenzamide, 99% 2,6-Difluor...

uorobenzamide

Fluorine benzaMide 2, 6-2

2,6-difluoro-benzamid

2,6-DIFLUOROBENZAMIDE

2，6-difluorobenzaminde

2,6-Difluorobenzamide&gt

Lufenuron Metabolite CGA149772

Benzamide, 2,6-difluoro-

2,6-Difluorobenzoamide

18063-03-1

C7H5NOF2

Organic Building Blocks

Carbonyl Compounds

Building Blocks

Amides

Carbonyl Compounds

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Organic Building Blocks

intermediate

Aryl Fluorinated Building Blocks

Building Blocks

Carbonyl Compounds

Chemical Synthesis

Fluorinated Building Blocks

Organic Building Blocks

Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

18063-03-1