1-Tritylimidazole-4-carboxaldehyde
- Product Name
- 1-Tritylimidazole-4-carboxaldehyde
- CAS No.
- 33016-47-6
- Chemical Name
- 1-Tritylimidazole-4-carboxaldehyde
- Synonyms
- AKOS 215-50;RARECHEM AN KA 0027;4-FORMYL-1-TRITYLIMIDAZOLE;4-formyl-1-trithyl-imidazole;4-Formyl-1-trityl-1H-imidazole;1-tritylimidazole-4-carbaldehyde;1-Trityl-imidazol-4-carbaldehyde;1-TRITYL-IMDAZOLE-4-CARBOXADEHYDE;1-TRITYLIMIDAZOLE-4-CARBOXALDEHYDE;1-tritylimidazole-4-carboxaldehude
- CBNumber
- CB5387090
- Molecular Formula
- C23H18N2O
- Formula Weight
- 338.4
- MOL File
- 33016-47-6.mol
1-Tritylimidazole-4-carboxaldehyde Property
- Melting point:
- 180-190°C
- Boiling point:
- 502.8±45.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Acetonitrile (Slightly), Methanol (Slightly)
- form
- solid
- pka
- 2.28±0.61(Predicted)
- color
- White to brown
- InChI
- InChI=1S/C23H18N2O/c26-17-22-16-25(18-24-22)23(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-18H
- InChIKey
- YQYLLBSWWRWWAY-UHFFFAOYSA-N
- SMILES
- C1N(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C=C(C=O)N=1
- CAS DataBase Reference
- 33016-47-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37
- Hazard Note
- Irritant
- HS Code
- 29332900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- T2204
- Product name
- 1-Tritylimidazole-4-carboxaldehyde
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $20
- Updated
- 2025/07/31
- Product number
- T2204
- Product name
- 1-Tritylimidazole-4-carboxaldehyde
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $87
- Updated
- 2025/07/31
- Product number
- T889205
- Product name
- N-(Triphenylmethyl)-4-imidazolecarboxaldehyde
- Packaging
- 25g
- Price
- $380
- Updated
- 2021/12/16
- Product number
- OR10596
- Product name
- 1-Trityl-1H-imidazole-4-carboxaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 4H15-1-H6
- Product name
- 1-Trityl-1H-imidazole-4-carboxaldehyde
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
1-Tritylimidazole-4-carboxaldehyde Chemical Properties,Usage,Production
Uses
1-Tritylimidazole-4-carboxaldehyde is used in the synthesis of histamine and girolline
Synthesis
76-83-5
3034-50-2
33016-47-6
Example 33: Synthesis of 1-trityl-1H-imidazole-4-carbaldehyde 4-Imidazolecarboxaldehyde (30.0 g, 0.30 mol) was dissolved in DMF (200 mL) and triethylamine (70 mL, 0.375 mol) was added slowly under cooling in an ice bath. Triphenylchloromethane (105 g, 0.375 mol) was then added in batches and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the solvent was removed by vacuum evaporation and the residue was washed with anhydrous ether (4 x 50 mL) and dried to give a yellow solid 1-tritylimidazole-4-carboxaldehyde (100 g, 100%).
References
[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 23, p. 7993 - 8002
[2] Patent: WO2008/4096, 2008, A1. Location in patent: Page/Page column 79
[3] Journal of Medicinal Chemistry, 2002, vol. 45, # 1, p. 177 - 188
[4] European Journal of Organic Chemistry, 2015, vol. 2015, # 18, p. 3957 - 3962
[5] Patent: US2004/122018, 2004, A1. Location in patent: Page 317
1-Tritylimidazole-4-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Tritylimidazole-4-carboxaldehyde manufacturers
- Product
- 1-Tritylimidazole-4-carboxaldehyde 33016-47-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- 1-Tritylimidazole-4-carboxaldehyde 33016-47-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-14
- Product
- 1-Tritylimidazole-4-carboxaldehyde 33016-47-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%Min
- Supply Ability
- 1000kg
- Release date
- 2023-03-13