ChemicalBook > CAS DataBase List > 1-Tritylimidazole-4-carboxaldehyde

1-Tritylimidazole-4-carboxaldehyde

Product Name
1-Tritylimidazole-4-carboxaldehyde
CAS No.
33016-47-6
Chemical Name
1-Tritylimidazole-4-carboxaldehyde
Synonyms
AKOS 215-50;RARECHEM AN KA 0027;4-FORMYL-1-TRITYLIMIDAZOLE;4-formyl-1-trithyl-imidazole;4-Formyl-1-trityl-1H-imidazole;1-tritylimidazole-4-carbaldehyde;1-Trityl-imidazol-4-carbaldehyde;1-TRITYL-IMDAZOLE-4-CARBOXADEHYDE;1-TRITYLIMIDAZOLE-4-CARBOXALDEHYDE;1-tritylimidazole-4-carboxaldehude
CBNumber
CB5387090
Molecular Formula
C23H18N2O
Formula Weight
338.4
MOL File
33016-47-6.mol
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1-Tritylimidazole-4-carboxaldehyde Property

Melting point:
180-190°C
Boiling point:
502.8±45.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Acetonitrile (Slightly), Methanol (Slightly)
form 
solid
pka
2.28±0.61(Predicted)
color 
White to brown
InChI
InChI=1S/C23H18N2O/c26-17-22-16-25(18-24-22)23(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-18H
InChIKey
YQYLLBSWWRWWAY-UHFFFAOYSA-N
SMILES
C1N(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C=C(C=O)N=1
CAS DataBase Reference
33016-47-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-37
Hazard Note 
Irritant
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2204
Product name
1-Tritylimidazole-4-carboxaldehyde
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
T2204
Product name
1-Tritylimidazole-4-carboxaldehyde
Purity
>98.0%(HPLC)
Packaging
1g
Price
$87
Updated
2025/07/31
TRC
Product number
T889205
Product name
N-(Triphenylmethyl)-4-imidazolecarboxaldehyde
Packaging
25g
Price
$380
Updated
2021/12/16
AK Scientific
Product number
J94785
Product name
1-Tritylimidazole-4-carboxaldehyde
Packaging
100g
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0018452
Product name
1-TRITYL-1H-IMIDAZOLE-4-CARBOXALDEHYDE
Purity
95.00%
Packaging
5G
Price
$849.71
Updated
2021/12/16
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1-Tritylimidazole-4-carboxaldehyde Chemical Properties,Usage,Production

Uses

1-Tritylimidazole-4-carboxaldehyde is used in the synthesis of histamine and girolline

Synthesis

76-83-5

3034-50-2

33016-47-6

Example 33: Synthesis of 1-trityl-1H-imidazole-4-carbaldehyde 4-Imidazolecarboxaldehyde (30.0 g, 0.30 mol) was dissolved in DMF (200 mL) and triethylamine (70 mL, 0.375 mol) was added slowly under cooling in an ice bath. Triphenylchloromethane (105 g, 0.375 mol) was then added in batches and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the solvent was removed by vacuum evaporation and the residue was washed with anhydrous ether (4 x 50 mL) and dried to give a yellow solid 1-tritylimidazole-4-carboxaldehyde (100 g, 100%).

References

[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 23, p. 7993 - 8002
[2] Patent: WO2008/4096, 2008, A1. Location in patent: Page/Page column 79
[3] Journal of Medicinal Chemistry, 2002, vol. 45, # 1, p. 177 - 188
[4] European Journal of Organic Chemistry, 2015, vol. 2015, # 18, p. 3957 - 3962
[5] Patent: US2004/122018, 2004, A1. Location in patent: Page 317

1-Tritylimidazole-4-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Tritylimidazole-4-carboxaldehyde Suppliers

TCI Chemicals (India) Pvt. Ltd.
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Alfa Aesar
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SynZeal Research Pvt Ltd
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Pharma Affiliates
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Pharmaffiliates Analytics and Synthetics P. Ltd
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CHEMSWORTH
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A.J Chemicals
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View Lastest Price from 1-Tritylimidazole-4-carboxaldehyde manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-Tritylimidazole-4-carboxaldehyde 33016-47-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08
Shaanxi Dideu Medichem Co. Ltd
Product
1-Tritylimidazole-4-carboxaldehyde 33016-47-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-14
LY Global chemicals co.,ltd .
Product
1-Tritylimidazole-4-carboxaldehyde 33016-47-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%Min
Supply Ability
1000kg
Release date
2023-03-13

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