ChemicalBook > CAS DataBase List > S- (+)-Rolipram

S- (+)-Rolipram

Product Name
S- (+)-Rolipram
CAS No.
85416-73-5
Chemical Name
S- (+)-Rolipram
Synonyms
(+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4(Risperidone EP Impurity D-d4);(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CBNumber
CB5397417
Molecular Formula
C16H21NO3
Formula Weight
275.34
MOL File
85416-73-5.mol
More
Less

S- (+)-Rolipram Property

Melting point:
133-136℃
Density 
1.155
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form 
White to off-white solid.
color 
White to Almost white
More
Less

Safety

HS Code 
2933.79.1500
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
R0183
Product name
(S)-(+)-Rolipram
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$178
Updated
2024/03/01
TCI Chemical
Product number
R0183
Product name
(S)-(+)-Rolipram
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$622
Updated
2024/03/01
TRC
Product number
R640045
Product name
S-(+)-Rolipram
Packaging
10mg
Price
$200
Updated
2021/12/16
ApexBio Technology
Product number
A4349
Product name
S-(+)-Rolipram
Packaging
25mg
Price
$190
Updated
2021/12/16
AK Scientific
Product number
X5034
Product name
S-(+)-Rolipram
Packaging
50mg
Price
$232
Updated
2021/12/16
More
Less

S- (+)-Rolipram Chemical Properties,Usage,Production

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

S- (+)-Rolipram Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ascent Scientific
Tel
4401179829988
Fax
4402030 700 369
Email
customerservice@ascentscientific.co.uk
Country
United Kingdom
ProdList
279
Advantage
60
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
More
Less

View Lastest Price from S- (+)-Rolipram manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
S- (+)-Rolipram 85416-73-5
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99% HPLC
Supply Ability
2000tons
Release date
2019-12-30
Career Henan Chemical Co
Product
S- (+)-Rolipram 85416-73-5
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100KG
Release date
2020-03-13

85416-73-5, S- (+)-RolipramRelated Search:


  • (S)-(+)-ROLIPRAM
  • (4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one
  • Rolipram (S)-(+)-
  • (4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
  • (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • (+)-ROLIPRAM;(S)-ROLIPRAM
  • (4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone
  • (S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
  • (4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
  • 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)-
  • (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
  • S- (+)-Rolipram USP/EP/BP
  • S- (+)-Rolipram (ME-3167
  • (+)-Rolipram
  • TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis
  • Risperidone Impurity 4-d4(Risperidone EP Impurity D-d4)
  • 85416-73-5
  • Signalling
  • Cyclic Nucleotide related
  • Inhibitors