S- (+)-Rolipram

Product Name: S- (+)-Rolipram
CAS No.: 85416-73-5
Chemical Name: S- (+)-Rolipram
Synonyms: (+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CBNumber: CB5397417
Molecular Formula: C16H21NO3
Formula Weight: 275.34
MOL File: 85416-73-5.mol

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S- (+)-Rolipram Property

Melting point:: 133-136℃
Density: 1.155
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form: White to off-white solid.
color: White to Almost white

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Safety

HS Code: 2933.79.1500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: R0183
Product name: (S)-(+)-Rolipram
Purity: >98.0%(HPLC)
Packaging: 10mg
Price: $178
Updated: 2024/03/01

TCI Chemical

Product number: R0183
Product name: (S)-(+)-Rolipram
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $622
Updated: 2024/03/01

TRC

Product number: R640045
Product name: S-(+)-Rolipram
Packaging: 10mg
Price: $200
Updated: 2021/12/16

ApexBio Technology

Product number: A4349
Product name: S-(+)-Rolipram
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ApexBio Technology

Product number: A4349
Product name: S-(+)-Rolipram
Packaging: 10mM(in 1mL DMSO)
Price: $55
Updated: 2021/12/16

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S- (+)-Rolipram Chemical Properties,Usage,Production

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

Preparation Products

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S- (+)-Rolipram Suppliers

China 56 Germany 3 India 2 Japan 1 The Netherlands 1 United Kingdom 6 United States 19 Global 88

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Ascent Scientific

Tel: 4401179829988
Fax: 4402030 700 369
Email: customerservice@ascentscientific.co.uk
Country: United Kingdom
ProdList: 279
Advantage: 60

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4552
Advantage: 62

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

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View Lastest Price from S- (+)-Rolipram manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: S- (+)-Rolipram 85416-73-5
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99% HPLC
Supply Ability: 2000tons
Release date: 2019-12-30

Career Henan Chemical Co

Product: S- (+)-Rolipram 85416-73-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100KG
Release date: 2020-03-13

85416-73-5, S- (+)-RolipramRelated Search:

ZARDAVERINE RO 20-1724 Roflumilast 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE ETAZOLATE BRL 50481 Vinpocetine ZAPRINAST Cilostazol CILOSTAMIDE AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram 4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

(S)-(+)-ROLIPRAM

(4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one

Rolipram (S)-(+)-

(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(+)-ROLIPRAM;(S)-ROLIPRAM

(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone

(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)-

(S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one

S- (+)-Rolipram USP/EP/BP

S- (+)-Rolipram (ME-3167

(+)-Rolipram

TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis

Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）

85416-73-5

Signalling

Cyclic Nucleotide related

Inhibitors