ChemicalBook > CAS DataBase List > S- (+)-Rolipram

S- (+)-Rolipram

Product Name
S- (+)-Rolipram
CAS No.
85416-73-5
Chemical Name
S- (+)-Rolipram
Synonyms
(+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CBNumber
CB5397417
Molecular Formula
C16H21NO3
Formula Weight
275.34
MOL File
85416-73-5.mol
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S- (+)-Rolipram Property

Melting point:
133-136℃
Density 
1.155
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form 
White to off-white solid.
color 
White to Almost white
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Safety

HS Code 
2933.79.1500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
R0183
Product name
(S)-(+)-Rolipram
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$178
Updated
2024/03/01
TCI Chemical
Product number
R0183
Product name
(S)-(+)-Rolipram
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$622
Updated
2024/03/01
TRC
Product number
R640045
Product name
S-(+)-Rolipram
Packaging
10mg
Price
$200
Updated
2021/12/16
ApexBio Technology
Product number
A4349
Product name
S-(+)-Rolipram
Packaging
25mg
Price
$190
Updated
2021/12/16
AK Scientific
Product number
X5034
Product name
S-(+)-Rolipram
Packaging
50mg
Price
$232
Updated
2021/12/16
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S- (+)-Rolipram Chemical Properties,Usage,Production

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

Preparation Products

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S- (+)-Rolipram Suppliers

China 56 Germany 3 India 2 Japan 1 The Netherlands 1 United Kingdom 6 United States 19 Global 88
J & K SCIENTIFIC LTD.
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View Lastest Price from S- (+)-Rolipram manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
S- (+)-Rolipram 85416-73-5
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99% HPLC
Supply Ability
2000tons
Release date
2019-12-30
Career Henan Chemical Co
Product
S- (+)-Rolipram 85416-73-5
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100KG
Release date
2020-03-13

85416-73-5, S- (+)-RolipramRelated Search:

ZARDAVERINE RO 20-1724 Roflumilast 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE ETAZOLATE BRL 50481 Vinpocetine ZAPRINAST Cilostazol CILOSTAMIDE AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram 4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

  • (S)-(+)-ROLIPRAM
  • (4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one
  • Rolipram (S)-(+)-
  • (4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
  • (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • (+)-ROLIPRAM;(S)-ROLIPRAM
  • (4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone
  • (S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
  • (4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
  • 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)-
  • (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
  • S- (+)-Rolipram USP/EP/BP
  • S- (+)-Rolipram (ME-3167
  • (+)-Rolipram
  • TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis
  • Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）
  • 85416-73-5
  • Signalling
  • Cyclic Nucleotide related
  • Inhibitors