ChemicalBook > CAS DataBase List > 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE

1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE

Product Name
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE
CAS No.
439811-37-7
Chemical Name
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE
Synonyms
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE;tert-butyl 4-(4-broMobenzoyl)piperidine-1-carboxylate;tert-butyl 4-[(4-broMophenyl)carbonyl]piperidine-1-carboxylate;4-(4-bromobenzoyl)piperidine-1-carboxylic acid tert-butyl ester;1-Piperidinecarboxylic acid, 4-(4-bromobenzoyl)-, 1,1-dimethylethyl ester
CBNumber
CB5413232
Molecular Formula
C17H22BrNO3
Formula Weight
368.27
MOL File
439811-37-7.mol
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1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE Property

Boiling point:
452.3±40.0 °C(Predicted)
Density 
1.325±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-2.47±0.40(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B200940
Product name
1-Boc-4-(4-bromo-benzoyl)-piperidine
Packaging
100mg
Price
$100
Updated
2021/12/16
TRC
Product number
B200940
Product name
1-Boc-4-(4-bromo-benzoyl)-piperidine
Packaging
250mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB51872
Product name
1-Boc-4-(4-bromo-benzoyl)piperidine
Packaging
500mg
Price
$220
Updated
2021/12/16
Matrix Scientific
Product number
074243
Product name
1-Boc-4-(4-Bromobenzoyl)piperidine
Purity
95+%
Packaging
250mg
Price
$231
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB51872
Product name
1-Boc-4-(4-bromo-benzoyl)piperidine
Packaging
100mg
Price
$111
Updated
2021/12/16
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1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE Chemical Properties,Usage,Production

Synthesis

746550-66-3

24424-99-5

439811-37-7

Step 1. Synthesis of tert-butyl 4-(4-bromobenzoyl)-piperidine-1-carboxylate. To a 250 mL round bottom flask was added 4-(4-bromobenzoyl)piperidine (5 g, 20 mmol), tetrahydrofuran (30 mL), water (30 mL), sodium carbonate (10 g, 90 mmol) and di-tert-butyl dicarbonate (4.35 g, 20.0 mmol). The reaction mixture was stirred at room temperature for 2 h and then partitioned with ethyl acetate and water. The aqueous layer was extracted twice with ethyl acetate, the organic phases were combined, washed with brine, dried, filtered and concentrated to give 7.1 g (100% yield) of tert-butyl 4-(4-bromobenzoyl)-piperidine-1-carboxylate.

References

[1] Patent: WO2016/205590, 2016, A1. Location in patent: Paragraph 00596
[2] Patent: WO2013/147711, 2013, A1. Location in patent: Page/Page column 231
[3] Patent: US2014/371199, 2014, A1. Location in patent: Paragraph 0801
[4] Patent: US2005/54628, 2005, A1. Location in patent: Page/Page column 23-24
[5] Patent: US2005/49269, 2005, A1. Location in patent: Page/Page column 12; 21

1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE Suppliers

China 53 Germany 1 India 1 United Kingdom 1 United States 12 Global 68
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE manufacturers

Career Henan Chemical Co
Product
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE 439811-37-7
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08
Career Henan Chemical Co
Product
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE 439811-37-7
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-08

439811-37-7, 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINERelated Search:

1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE 1-Benzhydrylazetane-3-carbonitrile 1-BOC-2-PHENYL-PIPERIDIN-4-ONE (4-OXO-4-PHENYL-BUTYL)-CARBAMIC ACID TERT-BUTYL ESTER (4-bromophenyl)(piperidin-4-yl)methanone 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

  • 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE
  • tert-butyl 4-(4-broMobenzoyl)piperidine-1-carboxylate
  • tert-butyl 4-[(4-broMophenyl)carbonyl]piperidine-1-carboxylate
  • 1-Piperidinecarboxylic acid, 4-(4-bromobenzoyl)-, 1,1-dimethylethyl ester
  • 4-(4-bromobenzoyl)piperidine-1-carboxylic acid tert-butyl ester
  • 439811-37-7