ChemicalBook > CAS DataBase List > 4-isopropylcyclohexanol

4-isopropylcyclohexanol

Product Name
4-isopropylcyclohexanol
CAS No.
4621-04-9
Chemical Name
4-isopropylcyclohexanol
Synonyms
APO PATCHONE;APOPATCHONE, IFF;Folrosia 5094001;TIMTEC-BB SBB008023;4-ISPROPYLCYCLOHEXANOL;Isopropyl cyclohexanol;p-isopropyl-cyclohexano;P-ISOPROPYL CYCLOHEXANOL;4-ISO-PROPYLCYCLOHEXANOL;Isopropylcyclohexanol, p-
CBNumber
CB5428740
Molecular Formula
C9H18O
Formula Weight
142.24
MOL File
4621-04-9.mol
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4-isopropylcyclohexanol Property

Melting point:
36.9°C (estimate)
Boiling point:
110°C/22mmHg(lit.)
Density 
0.9103 (estimate)
vapor pressure 
4.73-6.3Pa at 20-25℃
refractive index 
gt. 1.4660 to 1.4700
Flash point:
95 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Almost insoluble in water, soluble in alcohol and oils
form 
clear liquid
pka
15.30±0.40(Predicted)
color 
Colorless to Almost colorless
Odor
at 10.00 % in dipropylene glycol. leather red rose green dusty weedy metallic
Odor Type
leathery
LogP
2.7-2.8 at 35℃
Surface tension
36.7mN/m at 1g/L and 20℃
EPA Substance Registry System
Cyclohexanol, 4-(1-methylethyl)- (4621-04-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-39
RTECS 
GV9620000
HS Code 
2906190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0780
Product name
4-Isopropylcyclohexanol (cis- and trans- mixture)
Purity
>98.0%(GC)
Packaging
5g
Price
$149
Updated
2025/07/31
AK Scientific
Product number
6357AB
Product name
4-Isopropylcyclohexanol
Packaging
5g
Price
$255
Updated
2021/12/16
Matrix Scientific
Product number
172155
Product name
4-Iso-Propylcyclohexanol
Packaging
25g
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
172155
Product name
4-Iso-Propylcyclohexanol
Packaging
100g
Price
$352
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
FFG0002053
Product name
4-ISO-PROPYLCYCLOHEXANOL
Purity
99.00%
Packaging
25G
Price
$1158.18
Updated
2021/12/16
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4-isopropylcyclohexanol Chemical Properties,Usage,Production

Uses

4-isopropylcyclohexanol has been suggested for use in perfume compositions on account of its power, low cost, and stability in soap. It has acceptable effects upon Lavender, Pine and even on Rose type fragrances for such purpose, but it needs proper blending with sweetening materials of similar volatility, e.g. Linalool, Phenylethyl alcohol, Anethole, Citronellol, esters, etc. It blends well with the conventional Fougère materials and with many of the newer Cyclohexane derivatives.

Preparation

1) by hydrogenation of para-iso-Propyl phenol.
2) by electrolytic reduction of Cryptone, which can be obtained as an isolate from Eucalyptus oil fractions or certain Pine needle oils.

Biochem/physiol Actions

4-isopropylcyclohexanol (4-iPr-CyH-OH), a novel analgesic compound ,  which inhibited TRPV1, TRPA1, TRPM8, TRPV4 and ANO1, as well as mitigated capsaicin-induced pain-related behaviors in mice. Moreover, the absence of an agonist effect for 4-iPr-CyH-OH on these five channels may reduce side effects and dosages[1].

References

[1] Yasunori Takayama, M. Tominaga, H. Furue. “4-isopropylcyclohexanol has potential analgesic effects through the inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities.” Scientific Reports (2017).

4-isopropylcyclohexanol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-isopropylcyclohexanol manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-ISO-PROPYLCYCLOHEXANOL 4621-04-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-18
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-ISO-PROPYLCYCLOHEXANOL 4621-04-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-14
Shaanxi Dideu Medichem Co. Ltd
Product
4-isopropylcyclohexanol 4621-04-9
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-08-08

4621-04-9, 4-isopropylcyclohexanolRelated Search:


  • APO PATCHONE
  • 4-ISO-PROPYLCYCLOHEXANOL
  • 4-ISPROPYLCYCLOHEXANOL
  • P-ISOPROPYL CYCLOHEXANOL
  • PARA ISOPROPYL CYCLOHEXANOL
  • TIMTEC-BB SBB008023
  • 4-(1-methylethyl)-cyclohexano
  • 4-(1-methylethyl)-Cyclohexanol
  • 4-Isopropylcyclohexanol (Isomer 1)
  • 4-Isopropylcyclohexanol (Isomer 2)
  • Cyclohexanol, 4-isopropyl-
  • Cyclohexanol, p-isopropyl-
  • p-isopropyl-cyclohexano
  • Cyclohexanol, 4-(1-methylethyl)-
  • Isopropylcyclohexanol, p-
  • 4-ISPROPYLCYCLOHEXANOL 95%
  • APOPATCHONE, IFF
  • 4-ISO-PROPYLCYCLOHEXANOL ---99% ISOMER MIXTURE, D25 0.916, N20 1.4679---
  • 4-propan-2-ylcyclohexan-1-ol
  • 4-Isopropylcyclohexanol (cis- and trans- mixture)
  • 4-Isopropylcyclohexanol (<i>cis</i>- and<i>trans</i>- Mixture)
  • 4-Isopropylcyclohexanol (<i>cis</i>- andtrans- Mixture)
  • Isopropyl cyclohexanol
  • 4-Isopropylcyclohexanol(cis-andtrans-mixture)&gt
  • Folrosia 5094001
  • 4-(propan-2-yl)cyclohexan-1-ol, Mixture of diastereomers
  • 4621-04-9
  • 621-04-9