AZODICARBOXYLIC BISMORPHOLIDE
- Product Name
- AZODICARBOXYLIC BISMORPHOLIDE
- CAS No.
- 10465-82-4
- Chemical Name
- AZODICARBOXYLIC BISMORPHOLIDE
- Synonyms
- NSC 356022;AZODICARBOXYLIC DIMORPHOLIDE;AZODICARBOXYLIC BISMORPHOLIDE;4,4'-Azodicarbonylbis(morpholine);Azodicarboxylic dimorpholide >=98.0% (N);Diazene-1,2-diylbis(morpholinomethanone);Methanone,1,1'-(1,2-diazenediyl)bis[1-(4-morpholinyl)-;Methanone,1,1'-(1,2-diazenediyl)bis[1-(4-morpholinyl)-
- CBNumber
- CB5454231
- Molecular Formula
- C10H16N4O4
- Formula Weight
- 256.26
- MOL File
- 10465-82-4.mol
AZODICARBOXYLIC BISMORPHOLIDE Property
- Melting point:
- 141-143 °C
- Boiling point:
- 397.6±52.0 °C(Predicted)
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- -0.97±0.20(Predicted)
- Appearance
- Light yellow to yellow Solid
- BRN
- 1013753
- InChI
- InChI=1S/C10H16N4O4/c15-9(13-1-5-17-6-2-13)11-12-10(16)14-3-7-18-8-4-14/h1-8H2
- InChIKey
- CHAMTJKQPOMXTI-UHFFFAOYSA-N
- SMILES
- N(C(N1CCOCC1)=O)=NC(N1CCOCC1)=O
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- 11628
- Product name
- Azodicarboxylic dimorpholide
- Purity
- ≥98.0% (N)
- Packaging
- 5g
- Price
- $173.5
- Updated
- 2025/07/31
- Product number
- 100010
- Product name
- Diazene-1,2-diylbis(morpholinomethanone)
- Purity
- 95+%
- Packaging
- 1g
- Price
- $284
- Updated
- 2021/12/16
- Product number
- 100010
- Product name
- Diazene-1,2-diylbis(morpholinomethanone)
- Purity
- 95+%
- Packaging
- 5g
- Price
- $840
- Updated
- 2021/12/16
- Product number
- CHM0117295
- Product name
- AZODICARBOXYLIC DIMORPHOLIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $914.41
- Updated
- 2021/12/16
- Product number
- 1041AA
- Product name
- Diazene-1,2-diylbis(morpholinomethanone)
- Packaging
- 1g
- Price
- $91
- Updated
- 2021/12/16
AZODICARBOXYLIC BISMORPHOLIDE Chemical Properties,Usage,Production
Uses
Azodicarboxylic dimorpholide has been used in the galanthamine ring system reaction that utilizes an intramolecular Heck reaction to establish the benzofuran ring system. Galanthamine exhibits potent acetylcholinesterase inhibitory activity and is important in the management of Alzheimer′s disease.
General Description
Azodicarboxylic dimorpholide is a yellow to dark yellow powder or crystals
Synthesis
110-91-8
1972-28-7
10465-82-4
To a stirred mixture of diethyl azodicarboxylate (40 wt% toluene solution, 5 mL, 11.5 mmol, 1 eq.) and ether (25 mL) was slowly added an ether solution (25 mL) of morpholine (1.98 mL, 23 mmol, 2 eq.) through a dropping funnel at 0 °C, the dropwise addition process continued for 3 hours. The reaction mixture was then continued to stir for 2 hours under slow warming to room temperature. The resulting yellow precipitate was collected by vacuum filtration, washed with cold ether and dried over a filter to afford azodicarbonyl dimorpholine (ADDM) as a yellow-orange solid (1.62 g, 55% yield). The NMR hydrogen spectrum (CDCl3, 400 MHz) data were as follows: δ 3.61 (multiple peaks, 4H, 2 × CH2), 3.74 (multiple peaks, 8H, 4 × CH2), 3.83 (multiple peaks, 4H, 2 × CH2).
References
[1] Tetrahedron Letters, 2013, vol. 54, # 35, p. 4624 - 4628
AZODICARBOXYLIC BISMORPHOLIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AZODICARBOXYLIC BISMORPHOLIDE manufacturers
- Product
- AZODICARBOXYLIC BISMORPHOLIDE 10465-82-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-06