ChemicalBook > CAS DataBase List > 1,1'-(Azodicarbonyl)-dipiperidine

1,1'-(Azodicarbonyl)-dipiperidine

Product Name
1,1'-(Azodicarbonyl)-dipiperidine
CAS No.
10465-81-3
Chemical Name
1,1'-(Azodicarbonyl)-dipiperidine
Synonyms
ADDP;1,1'-(AZODICARBONYL)DIPIPERIDINE;Diazene-1,2-diylbis(piperidin-1-ylMethanone);sr4077;NSC 356027;Azodicarboxylic;1,1'-(Azodicarbo;1,1'-(Azodicarbonyl);Diphenylpiperidylcarboxylate;AZODICARBOXYLIC DIPIPERIDIDE
CBNumber
CB8352693
Molecular Formula
C12H20N4O2
Formula Weight
252.31
MOL File
10465-81-3.mol
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1,1'-(Azodicarbonyl)-dipiperidine Property

Melting point:
132-136 °C(lit.)
Boiling point:
366.4±25.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), insol petroleum ether; sol ethanol, ether, THF
pka
-0?+-.0.20(Predicted)
form 
solid
color 
yellow
Water Solubility 
Slightly soluble in water.
BRN 
261917
InChI
InChI=1S/C12H20N4O2/c17-11(15-7-3-1-4-8-15)13-14-12(18)16-9-5-2-6-10-16/h1-10H2
InChIKey
OQJBFFCUFALWQL-UHFFFAOYSA-N
SMILES
N(C(N1CCCCC1)=O)=NC(N1CCCCC1)=O
CAS DataBase Reference
10465-81-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3234
WGK Germany 
3
TSCA 
No
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
255920
Product name
1,1′-(Azodicarbonyl)dipiperidine
Purity
99%
Packaging
5g
Price
$98.6
Updated
2024/03/01
Sigma-Aldrich
Product number
255920
Product name
1,1′-(Azodicarbonyl)dipiperidine
Purity
99%
Packaging
25g
Price
$224
Updated
2024/03/01
TCI Chemical
Product number
A1051
Product name
1,1'-(Azodicarbonyl)dipiperidine
Purity
>98.0%(N)
Packaging
5g
Price
$78
Updated
2024/03/01
TCI Chemical
Product number
A1051
Product name
1,1'-(Azodicarbonyl)dipiperidine
Purity
>98.0%(N)
Packaging
25g
Price
$309
Updated
2024/03/01
Alfa Aesar
Product number
H27719
Product name
1,1'-(Azodicarbonyl)dipiperidine, 97%
Packaging
5g
Price
$95.65
Updated
2024/03/01
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1,1'-(Azodicarbonyl)-dipiperidine Chemical Properties,Usage,Production

Description

1,1''-(Azodicarbonyl)dipiperidine (ADDP) is a reagent commonly used in the Mitsunobu reaction for the condensation of an alcohol and an acidic compound. It has been used as a reagent in the synthesis of G protein-coupled receptor 120 (GPR120) agonists with antidiabetic activity and peroxisome proliferator-activated receptor α (PPARα), PPARγ, and PPARδ triple agonists.

Chemical Properties

yellow crystalline powder

Uses

It is used in a study of the copper-catalyzed addition of aryboronic acids to azodicarboxyl derivatives providing aryl-substituted hydrazides. It is widely used reagent for the Mitsunobu reaction. It is reactant for preparation of polyfluoroalkylated tripyrazolylmethane ligands, (-)-Hygromycin A via Mitsunobu glycosylation, optically active α,α-disubstituted amino acids via Mitsunobu reaction, aza-β-lactams through [2+2] cycloaddition reactions, glycosyl disulfides, pyridine ether PPAR agonists, S-glycosyl amino acid, building blocks for combinatorial neoglycopeptide synthesis and is a histamine H3 receptor antagonists. It is a reactant for Mitsunobu inversion reactions.

Reactions

1,1'-(Azodicarbonyl)-dipiperidine can selectively oxidizes a variety of alcohols to the corresponding aldehydes or ketones under basic conditions.

1,1'-(Azodicarbonyl)-dipiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1'-(Azodicarbonyl)-dipiperidine Suppliers

Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928 18306219933
Fax
0512-68417696
Email
paul@highfine.com
Country
China
ProdList
499
Advantage
75
Nanjing Yiyuan
Tel
18061915908
Email
945992976@qq.com
Country
China
ProdList
25
Advantage
58
Suzhou BEC Biological Technology Co., Ltd
Tel
+86-512-68095917 13862064516
Fax
+86-512-68417933
Email
sales@bek.com.cn
Country
China
ProdList
146
Advantage
59
SuZhou Jonathan New Material Technology Co., Ltd.
Tel
0512-68312916,63926215 18912725070
Fax
0512-68417933
Email
jon@jonnmt.com
Country
China
ProdList
114
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Winsome Chemical Limited
Tel
025-84651981 18652010011
Email
sales@nastchem.com
Country
China
ProdList
75
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 1,1'-(Azodicarbonyl)-dipiperidine manufacturers

Henan Fengda Chemical Co., Ltd
Product
1,1'-(azodicarbonyl)-dipiperidine 10465-81-3
Price
US $30.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-26
Hangzhou ICH Biofarm Co., Ltd
Product
1,1'-(Azodicarbonyl)-dipiperidine 10465-81-3
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-09
Qiuxian Baitai New Material Co., LTD
Product
1,1'-(Azodicarbo 10465-81-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500ton/Month
Release date
2021-07-29

10465-81-3, 1,1'-(Azodicarbonyl)-dipiperidineRelated Search:


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  • 10465-81-3
  • Heterocyclic Building Blocks
  • C-X Bond Formation (Non-Halogen)
  • Azodicarboxylates & Amides
  • Mitsunobu Reaction
  • Building Blocks
  • Synthetic Reagents
  • Piperidines
  • Mitsunobu
  • API intermediates
  • Azodicarboxylates & Amides
  • Mitsunobu Reaction
  • Synthetic Organic Chemistry