ChemicalBook > CAS DataBase List > 1,1'-(Azodicarbonyl)-dipiperidine

1,1'-(Azodicarbonyl)-dipiperidine

Product Name
1,1'-(Azodicarbonyl)-dipiperidine
CAS No.
10465-81-3
Chemical Name
1,1'-(Azodicarbonyl)-dipiperidine
Synonyms
ADDP;1,1'-(AZODICARBONYL)DIPIPERIDINE;Diazene-1,2-diylbis(piperidin-1-ylMethanone);sr4077;NSC 356027;Azodicarboxylic;1,1'-(Azodicarbo;1,1'-(Azodicarbonyl);Diphenylpiperidylcarboxylate;AZODICARBOXYLIC DIPIPERIDIDE
CBNumber
CB8352693
Molecular Formula
C12H20N4O2
Formula Weight
252.31
MOL File
10465-81-3.mol
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1,1'-(Azodicarbonyl)-dipiperidine Property

Melting point:
132-136 °C(lit.)
Boiling point:
366.4±25.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-0?+-.0.20(Predicted)
form 
solid
color 
yellow
Water Solubility 
Slightly soluble in water.
BRN 
261917
InChI
InChI=1S/C12H20N4O2/c17-11(15-7-3-1-4-8-15)13-14-12(18)16-9-5-2-6-10-16/h1-10H2
InChIKey
OQJBFFCUFALWQL-UHFFFAOYSA-N
SMILES
N(C(N1CCCCC1)=O)=NC(N1CCCCC1)=O
CAS DataBase Reference
10465-81-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3234
WGK Germany 
3
TSCA 
No
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
255920
Product name
1,1′-(Azodicarbonyl)dipiperidine
Purity
99%
Packaging
5g
Price
$98.6
Updated
2024/03/01
Sigma-Aldrich
Product number
255920
Product name
1,1′-(Azodicarbonyl)dipiperidine
Purity
99%
Packaging
25g
Price
$224
Updated
2024/03/01
TCI Chemical
Product number
A1051
Product name
1,1'-(Azodicarbonyl)dipiperidine
Purity
>98.0%(N)
Packaging
5g
Price
$78
Updated
2024/03/01
TCI Chemical
Product number
A1051
Product name
1,1'-(Azodicarbonyl)dipiperidine
Purity
>98.0%(N)
Packaging
25g
Price
$309
Updated
2024/03/01
Alfa Aesar
Product number
H27719
Product name
1,1'-(Azodicarbonyl)dipiperidine, 97%
Packaging
5g
Price
$95.65
Updated
2024/03/01
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1,1'-(Azodicarbonyl)-dipiperidine Chemical Properties,Usage,Production

Description

1,1''-(Azodicarbonyl)dipiperidine (ADDP) is a reagent commonly used in the Mitsunobu reaction for the condensation of an alcohol and an acidic compound. It has been used as a reagent in the synthesis of G protein-coupled receptor 120 (GPR120) agonists with antidiabetic activity and peroxisome proliferator-activated receptor α (PPARα), PPARγ, and PPARδ triple agonists.

Chemical Properties

yellow crystalline powder

Uses

It is used in a study of the copper-catalyzed addition of aryboronic acids to azodicarboxyl derivatives providing aryl-substituted hydrazides. It is widely used reagent for the Mitsunobu reaction. It is reactant for preparation of polyfluoroalkylated tripyrazolylmethane ligands, (-)-Hygromycin A via Mitsunobu glycosylation, optically active α,α-disubstituted amino acids via Mitsunobu reaction, aza-β-lactams through [2+2] cycloaddition reactions, glycosyl disulfides, pyridine ether PPAR agonists, S-glycosyl amino acid, building blocks for combinatorial neoglycopeptide synthesis and is a histamine H3 receptor antagonists. It is a reactant for Mitsunobu inversion reactions.

1,1'-(Azodicarbonyl)-dipiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1'-(Azodicarbonyl)-dipiperidine Suppliers

Americas 1 China 188 Czech Republic 1 Europe 3 Germany 2 India 4 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 7 United States 31 Global 244
Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 1,1'-(Azodicarbonyl)-dipiperidine manufacturers

Henan Fengda Chemical Co., Ltd
Product
1,1'-(azodicarbonyl)-dipiperidine 10465-81-3
Price
US $30.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-26
Hangzhou ICH Biofarm Co., Ltd
Product
1,1'-(Azodicarbonyl)-dipiperidine 10465-81-3
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-09
Qiuxian Baitai New Material Co., LTD
Product
1,1'-(Azodicarbo 10465-81-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500ton/Month
Release date
2021-07-29

10465-81-3, 1,1'-(Azodicarbonyl)-dipiperidineRelated Search:

N,N,N',N'-Tetramethylazodicarboxamide O-Phthalimide Diethyl azodicarboxylate Dimethyl phthalate DIPHENYLCARBAZONE 2,2'-Azobis(2-methylpropionitrile) Azodicarbonamide AZODICARBOXYLIC BISMORPHOLIDE Dibenzyl azodicarboxylate Diisopropyl azodicarboxylate Di-tert-Butyl azodicarboxylate Bis(4-chlorobenzyl) azodicarboxylate N-Formylpiperidine 1,1-DIETHYLUREA 1-CARBAMYLPIPERIDINE 1,1'-(Azodicarbonyl)-dipiperidine

  • Diphenylpiperidylcarboxylate
  • AZODICARBOXYLIC ACID DIPIPERIDYL ESTER
  • Azodicarboxylic
  • diazenedicarboxylic acid bis(N,N-piperidide)
  • 1,1-IAZODICARBONYL)DIPIPERIDINE
  • Azodicarboxylic acid dipiperidine,95%
  • 1,1'-(Azodicarbonyl)
  • 1,1'-(Azodicarbonyl)dipiperidine(ADDP)
  • 1,1'-(azodicarbonyl)piperidine
  • ADD, Azodicarboxylic acid dipiperidide
  • ADD, ADDP, Azodicarboxylic dipiperidide
  • ADDP (1,1-Aza dicarbonyl di piperidine)
  • 1,1'-(Azobiscarbonyl)dipiperidine
  • 1,1'-(Azodicarbonyl)bispiperidine
  • Bis(piperidinocarbonyl)diazene
  • Bis(piperidinocarbonyl)diimide
  • (E)-diazene-1,2-diylbis(piperidin-1-yl methanone)
  • Diazene-1,2-diylbis(piperidin-1-ylMethanone)
  • N-{[(piperidin-1-yl)carbonyl]iMino}piperidine-1-carboxaMide
  • (NE)-N-{[(E)-piperidine-1-carbonyl]imino}piperidine-1-carboxamide
  • 1,1'-(Azodicarbonyl)dipiperidine (ADDP), 97+%
  • ADDP
  • 1,1′-Azobis(N,N-pentamethyleneformamide)
  • NSC 356027
  • 1,1'-(Azodicarbonyl)dipiperidine 99%
  • 1,1′-(Azodicarbonyl)dipiperidine, >=99%
  • 1,1-(Azodicarbonyl)dipiperidine≥ 99%(N)
  • Methanone,1,1'-(1,2-diazenediyl)bis[1-(1-piperidinyl)-
  • sr4077
  • 1,1'-(AZODICARBONYL)DIPIPERIDINE
  • AZODICARBOXYLIC ACID DIPIPERIDIDE
  • Azodicarboxylic acid dipiperidine
  • AZODICARBOXYLIC DIPIPERIDIDE
  • (NE)-N-[oxo(1-piperidinyl)methyl]imino-1-piperidinecarboxamide
  • 1,1'-(Azodicarbonyl)dipiperidine &gt
  • (NE)-N-(piperidine-1-carbonylimino)piperidine-1-carboxamide
  • 1,1'-(Azodicarbo
  • 1,1'-(Azodicarbonyl)dipiperidine
  • 1,1’-(Azodicarbonyl)dipiperidine (ADDP)
  • 10465-81-3
  • Heterocyclic Building Blocks
  • C-X Bond Formation (Non-Halogen)
  • Azodicarboxylates & Amides
  • Mitsunobu Reaction
  • Building Blocks
  • Synthetic Reagents
  • Piperidines
  • Mitsunobu
  • API intermediates
  • Azodicarboxylates & Amides
  • Mitsunobu Reaction
  • Synthetic Organic Chemistry