D-Galactosamine pentaacetate
- Product Name
- D-Galactosamine pentaacetate
- CAS No.
- 76375-60-5
- Chemical Name
- D-Galactosamine pentaacetate
- Synonyms
- (2R,3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate;(3R,4R,5R,6R);D-GALACTOSAMINE PENTAACETATE;-3-Acetamido-6-(acetoxymethyl);D-Galactosamine pentaacetate USP/EP/BP;1,2,3,4,6-Penta-O-acetyl-D-galactosamine;tetrahydro-2H-pyran-2,4,5-triyl triacetate;2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-D-galac;C16H23NO10 D-Galactosamine pentaacetate 76375-60-5;2-Acetamido-2-deoxy-D-galactopyranose1,3,4,6-tetra-O-acetyl
- CBNumber
- CB5478482
- Molecular Formula
- C16H23NO10
- Formula Weight
- 389.35
- MOL File
- 76375-60-5.mol
D-Galactosamine pentaacetate Property
- Melting point:
- 230°C (dec.)
- Boiling point:
- 530.2±50.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly, Sonicated), DMSO (Slightly)
- form
- Solid
- pka
- 13.41±0.70(Predicted)
- color
- White to Pale Beige
- InChI
- InChI=1S/C16H23NO10/c1-7(18)17-13-15(25-10(4)21)14(24-9(3)20)12(6-23-8(2)19)27-16(13)26-11(5)22/h12-16H,6H2,1-5H3,(H,17,18)/t12-,13-,14+,15-,16?/m1/s1
- InChIKey
- OVPIZHVSWNOZMN-IWQYDBTJSA-N
- SMILES
- C1(OC(=O)C)O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1NC(C)=O
Safety
- HS Code
- 29400090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A151900
- Product name
- 2-Acetamido-2-deoxy-D-galactopyranose-1,3,4,6-tetra-O-acetate
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 001088
- Product name
- 2-Acetamido-2-deoxy-D-galactopyranose-1,3,4,6-tetra-O-acetate
- Packaging
- 250mg
- Price
- $319
- Updated
- 2021/12/16
- Product number
- 292483
- Product name
- 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-D-galactopyranose
- Packaging
- 1g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- MA07898
- Product name
- 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-D-galactopyranose
- Packaging
- 25g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- 099966
- Product name
- (3R,4R,5R,6R)-3-Acetamido-6-(acetoxymethyl)-tetrahydro-2H-pyran-2,4,5-triyl triacetate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $260
- Updated
- 2021/12/16
D-Galactosamine pentaacetate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Anti-tumor agent
Uses
Anti-tumour agent.
Synthesis
5432-46-2
108-24-7
3006-60-8
GENERAL STEPS: To a solution of 1,3,4,6-tetra-O-acetyl-2-amino-2-deoxy-D-glucopyranose hydrochloride (19.8 g, 67 mmol) in pyridine (130 mL) was added ethanoic anhydride (70 mL). The reaction mixture was stirred at room temperature overnight and subsequently concentrated under reduced pressure to afford (2S,3R,4R,5R,6R)-3-acetamido-6-(acetyloxymethyl)tetrahydro-2H-pyran-2,4,5-triacetic acid tris ester as a crude product as a yellow solid, which could be used in the next reaction without further purification. The above crude product (12 g, 26 mmol) was dissolved in acetone (130 mL) and aqueous hydrochloric acid (6.6 mL, 5N) was added slowly and dropwise at 0 °C. The reaction mixture was continued to be stirred at 0 °C for 1 h. The precipitate was subsequently removed by filtration. The filter cake was dried to give the target product as a white solid (7.50 g, 75% yield).
References
[1] European Journal of Organic Chemistry, 2012, # 9, p. 1699 - 1702
[2] Carbohydrate Research, 2015, vol. 413, p. 135 - 144
[3] Journal of Organic Chemistry, 1954, vol. 19, p. 1793,1798
[4] Chemische Berichte, 1931, vol. 64, p. 975,978
[5] Carbohydrate research, 1985, vol. 136, p. 309 - 323
D-Galactosamine pentaacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D-Galactosamine pentaacetate manufacturers
- Product
- D-Galactosamine pentaacetate 76375-60-5
- Price
- US $0.00/G
- Min. Order
- 1G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-17
- Product
- D-Galactosamine pentaacetate 76375-60-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 25
- Release date
- 2024-08-15
- Product
- D-Galactosamine pentaacetate 76375-60-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-29