2-Chloro-3-methoxypyridine

Product Name: 2-Chloro-3-methoxypyridine
CAS No.: 52605-96-6
Chemical Name: 2-Chloro-3-methoxypyridine
Synonyms: 2-CHLORO-3-METHOXYPYRIDINE;Pyridine, 2-chloro-3-Methoxy-;2-Chloro-3-methoxypyridine ,98%;2-chloro-3-methoxypyridine(SALTDATA: FREE);2-Chloro-3-methoxypyridine ISO 9001：2015 REACH
CBNumber: CB5482933
Molecular Formula: C6H6ClNO
Formula Weight: 143.57
MOL File: 52605-96-6.mol

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2-Chloro-3-methoxypyridine Property

Melting point:: 90-92°C
Boiling point:: 210.6±20.0 °C(Predicted)
Density: 1.210±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: -0.51±0.10(Predicted)
form: crystalline solid
color: Light orange
Water Solubility: Insoluble in water.
BRN: 115568
InChI: InChI=1S/C6H6ClNO/c1-9-5-3-2-4-8-6(5)7/h2-4H,1H3
InChIKey: CCVNZKGBNUPYPG-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=CC=C1OC
CAS DataBase Reference: 52605-96-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39-37
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C596678
Product name: 2-Chloro-3-methoxypyridine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK249377
Product name: 2-Chloro-3-methoxypyridine
Purity: 98%
Packaging: 1g
Price: $91
Updated: 2021/12/16

Matrix Scientific

Product number: 072879
Product name: 2-Chloro-3-methoxypyridine
Purity: 95+%
Packaging: 5g
Price: $97
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC55508
Product name: 2-Chloro-3-methoxypyridine
Packaging: 2g
Price: $100.7
Updated: 2021/12/16

AK Scientific

Product number: L227
Product name: 2-Chloro-3-methoxypyridine
Packaging: 10g
Price: $110
Updated: 2021/12/16

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2-Chloro-3-methoxypyridine Chemical Properties,Usage,Production

Chemical Properties

White to off-white solid

Uses

It is a pharmaceutical raw material and also used in medicine.

Synthesis

6636-78-8

74-88-4

52605-96-6

Step 1: 2-Chloro-3-hydroxypyridine (2.59 g, 20 mmol), iodomethane (2.98 g, 21 mmol) and potassium carbonate (K2CO3, 5.52 g, 40 mmol) were added to N,N-dimethylformamide (DMF, 50 mL). The reaction mixture was stirred at 60 °C for 4 hours. After completion of the reaction, it was cooled to room temperature and the mixture was poured into water and extracted with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford 2-chloro-3-methoxypyridine (2.58 g, 90% yield). Mass spectrum (ESI) m/z: 144.0 [M + H]+.

References

[1] Patent: CN107286084, 2017, A. Location in patent: Paragraph 0008
[2] European Journal of Organic Chemistry, 2012, # 31, p. 6248 - 6259,12
[3] European Journal of Organic Chemistry, 2012, # 31, p. 6248 - 6259
[4] Patent: EP2952510, 2015, A1. Location in patent: Paragraph 0120
[5] Patent: WO2011/33265, 2011, A1. Location in patent: Page/Page column 107

2-Chloro-3-methoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-3-methoxypyridine Suppliers

China 151 Germany 2 India 4 Sweden 1 United Kingdom 6 United States 25 Global 189

Shanghai yirong biology science and technology co., ltd

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LEADMEDPHARM CO.,LTD

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Pure Chemistry Scientific Inc.

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View Lastest Price from 2-Chloro-3-methoxypyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Chloro-3-methoxypyridine 52605-96-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-04

Shanghai Yongzeng Technology Co.,Ltd

Product: 2-Chloro-3-methoxypyridine 52605-96-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1 tons
Release date: 2024-09-04

Henan Fengda Chemical Co., Ltd

Product: 2-Chloro-3-methoxypyridine 52605-96-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

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2-Chloro-3-methoxypyridine ,98%

2-chloro-3-methoxypyridine(SALTDATA: FREE)

2-CHLORO-3-METHOXYPYRIDINE

Pyridine, 2-chloro-3-Methoxy-

2-Chloro-3-methoxypyridine ISO 9001：2015 REACH

52605-96-6

Heterocycle-Pyridine series

Pyridine