N-(Trimethylsilyl)imidazole
- Product Name
- N-(Trimethylsilyl)imidazole
- CAS No.
- 18156-74-6
- Chemical Name
- N-(Trimethylsilyl)imidazole
- Synonyms
- TMSI;TMSIM;TRIMETHYLSILYLIMIDAZOLE;TSIM;TMS-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE;SIM;1-(TRIMETHYLSILYL)-1H-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%;Trimethylimidazosilane
- CBNumber
- CB5483743
- Molecular Formula
- C6H12N2Si
- Formula Weight
- 140.26
- MOL File
- 18156-74-6.mol
N-(Trimethylsilyl)imidazole Property
- Melting point:
- -42 °C
- Boiling point:
- 93-94 °C14 mm Hg(lit.)
- Density
- 0.957 g/mL at 20 °C
- refractive index
- n20/D 1.475(lit.)
- Flash point:
- 42 °F
- storage temp.
- Store below +30°C.
- solubility
- Chloroform
- form
- Liquid
- pka
- 7.96±0.10(Predicted)
- Specific Gravity
- 0.956
- color
- Clear colorless to yellow
- Water Solubility
- decomposes
- Sensitive
- Moisture Sensitive
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- BRN
- 606148
- Stability:
- Air and Moisture Sensitive
- InChIKey
- YKFRUJSEPGHZFJ-UHFFFAOYSA-N
- CAS DataBase Reference
- 18156-74-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 1h-Imidazole, 1-(trimethylsilyl)-(18156-74-6)
- EPA Substance Registry System
- 1H-Imidazole, 1-(trimethylsilyl)- (18156-74-6)
Safety
- Hazard Codes
- F,Xi,C
- Risk Statements
- 11-36/37/38-14-40-34-37-35-20/21/22
- Safety Statements
- 16-26-33-37/39-45-36/37/39
- RIDADR
- UN 1993 3/PG 2
- WGK Germany
- 3
- RTECS
- NI8700000
- F
- 10-21
- Autoignition Temperature
- 540 °C DIN 51794
- TSCA
- T
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29332990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.18204
- Product name
- N-(Trimethylsilyl)imidazole
- Purity
- for synthesis
- Packaging
- 25mL
- Price
- $88.1
- Updated
- 2024/03/01
- Product number
- 8.18204
- Product name
- N-(Trimethylsilyl)imidazole
- Purity
- for synthesis
- Packaging
- 100mL
- Price
- $267
- Updated
- 2024/03/01
- Product number
- 153583
- Product name
- 1-(Trimethylsilyl)imidazole
- Purity
- 96%
- Packaging
- 5ml
- Price
- $48.3
- Updated
- 2024/03/01
- Product number
- 153583
- Product name
- 1-(Trimethylsilyl)imidazole
- Purity
- 96%
- Packaging
- 25ml
- Price
- $128
- Updated
- 2024/03/01
- Product number
- 1.09771
- Product name
- N-(Trimethylsilyl)imidazole
- Purity
- for gas chromatography
- Packaging
- 5ml
- Price
- $214
- Updated
- 2024/03/01
N-(Trimethylsilyl)imidazole Chemical Properties,Usage,Production
Chemical Properties
Colorless transparent liquid
Physical properties
bp 93–94 °C/14 mmHg; fp 5 °C; d 0.956 g cm?3.
Uses
A general silylating agent, particularly for alcohols. An intermediate for the synthesis of imidazole derivatives.
Uses
Silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.1
Uses
N-(trimethylsilyl) imidazole (TMSim) is quite reactive with hydroxyl groups in a variety of analytes including a variety of lipids.As with other derivatization reactions,microwave heating can greatly improve process efficiency.
Uses
N-(Trimethylsilyl)imidazole is a silylating agent for alcohols and 1,3-dicarbonyl compounds; reaction with esters to give imidazolides; preparation of O-trimethylsilyl monothioacetals; aromatization of the A-ring of steroids. It participates in the reactions of Hydroxyl Silylation Reactions, Silyl Aminal Formation Reactions, Nitrogen Silylation Reactions, Acyl Imidazole Formation, Michael Addition Reactions, Substitution Reactions, Phosphoroimidazolidate Formation, and other uses.
Definition
ChEBI: A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a trimethylsilyl group. N-trimethylsilylimidazole is a derivatisation agent used in gas chromatography/mass spectrometry applications.
General Description
1-(Trimethylsilyl)imidazole (TMSIM) has high silyl donor ability. It does not react with amino groups and also does not help in formation of enol-ether on unprotected ketone groups. It is useful as a silylating agent for ecdysones, norepinephrine, dopamine, steroids, sugars, sugar phosphates and ketose isomers.
N-(Trimethylsilyl)imidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-(Trimethylsilyl)imidazole manufacturers
- Product
- N-(Trimethylsilyl)imidazole 18156-74-6
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-08
- Product
- N-(Trimethylsilyl)imidazole 18156-74-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 96%
- Supply Ability
- 20t
- Release date
- 2024-04-26
- Product
- N-(Trimethylsilyl)imidazole 18156-74-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-16