2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE

Product Name: 2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE
CAS No.: 341-88-8
Chemical Name: 2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE
Synonyms: hqno;kf8940;C04284;Pyo II;Antibiotic KF-8940;NZPACTGCRWDXCJ-UHFFFAOYSA-N;2-heptyl-4-quinolino1-oxide;2-Heptylquinolin-4-ol 1-oxide;2-Heptyl-4-quinolinol 1-oxide;4-Quinolinol, 2-heptyl-, 1-oxide
CBNumber: CB5503571
Molecular Formula: C16H21NO2
Formula Weight: 259.34
MOL File: 341-88-8.mol

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2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Property

Melting point:: 156-157°
Boiling point:: 445.8±37.0 °C(Predicted)
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Soluble in DMSO (up to 8 mg/ml with warming), or in Ethanol (up to 13 mg/ml with warming).
pka: 1.07±0.40(Predicted)
form: White to off-white crystalline solid.
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

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Safety

RTECS: VC5890000
Toxicity: LD50 intraperitoneal in mouse: 40mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15159
Product name: HQNO
Purity: ≥98%
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 15159
Product name: HQNO
Purity: ≥98%
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 15159
Product name: HQNO
Purity: ≥98%
Packaging: 50mg
Price: $435
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: INB0001935
Product name: 2-HEPTYL-4-HYDROXYQUINOLINE-1-OXIDE
Purity: 95.00%
Packaging: 5MG
Price: $499.44
Updated: 2021/12/16

ChemScene

Product number: CS-0104638
Product name: HQNO
Purity: 98.04%
Packaging: 50mg
Price: $320
Updated: 2021/12/16

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2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Chemical Properties,Usage,Production

Description

HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. HQNO inhibits NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR).

Uses

HQNO is a streptomycin antagonist. A naturally occurring antagonist of dihydrostreptomycin.

Definition

ChEBI: 2-heptyl-4-hydroxyquinoline N-oxide is an inhibitor of the mitochondrial respiratory chain at cytochrome bc1 and of photosynthetic electron flow immediately before cytochrome b559. It is a monohydroxyquinoline and a quinoline N-oxide.

References

References/Citations 1) Nakayama?et al. (1999),?Inhibitor studies of a new antibiotic, korormicin, 2-n-heptyl-4-hydroxyquinoline N-oxide and Ag+?toward the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus; Biol. Pharm. Bull.,?221064

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Suppliers

CHINA 55 Switzerland 1 United States 10 Global 66

TargetMol Chemicals Inc.

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341-88-8, 2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDERelated Search:

A23187 NONACTIN Nigericin sodium salt (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride Pyridine-N-oxide Pyridine-4-carboxylic acid N-oxide QUINOLINE N-OXIDE HYDRATE 2-Pentylpyridine 2-Butylpyridine 4-HYDROXY-2-METHYLQUINOLINE 4-Hydroxy-2-methylpyridine 2-Hexylpyridine Quinoline-N-oxide 4-HYDROXYPYRIDINE-1-OXIDE 2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE 2-Ethylquinoline 2-ETHYL-PYRIDINE 1-OXIDE 2-PICOLINE-N-OXIDE

2-(n-heptyl)-4-hydroxyquinolinen-oxide

2-heptyl-4-quinolino1-oxide

hqno

kf8940

2-Heptylquinolin-4-ol 1-oxide

Antibiotic KF-8940

Pyo II

C04284

NZPACTGCRWDXCJ-UHFFFAOYSA-N

2-Heptyl-4-quinolinol 1-oxide

4-Quinolinol, 2-heptyl-, 1-oxide

2-heptyl-4-hydroxyquinolin-1-ium-1-olate

electron,transport,Mitochondrial Metabolism,complex III,NDH-2,Inhibitor,HQNO,mitochondrial,chain,inhibit

341-88-8