m-PEG9-COOH
- Product Name
- m-PEG9-COOH
- CAS No.
- 2576495-35-5
- Chemical Name
- m-PEG9-COOH
- Synonyms
- mPEG8-PA;m-PEG9-COOH;4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid;2,5,8,11,14,17,20,23,26-Nonaoxanonacosan-29-oic acid;mPEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid;3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber
- CB55478210
- Molecular Formula
- C20H40O11
- Formula Weight
- 456.52
- MOL File
- 2576495-35-5.mol
m-PEG9-COOH Property
- Boiling point:
- 536.3±50.0 °C(Predicted)
- Density
- 1.111±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, sealed storage, away from moisture
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C20H40O11/c1-23-4-5-25-8-9-27-12-13-29-16-17-31-19-18-30-15-14-28-11-10-26-7-6-24-3-2-20(21)22/h2-19H2,1H3,(H,21,22)
- InChIKey
- HVDSDOIAPZITDA-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
m-PEG9-COOH Chemical Properties,Usage,Production
Uses
m-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
m-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
m-PEG9-COOH Preparation Products And Raw materials
Raw materials
Preparation Products
m-PEG9-COOH Suppliers
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View Lastest Price from m-PEG9-COOH manufacturers
- Product
- mPEG8-CH2CH2COOH 2576495-35-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2026-01-28
- Product
- m-PEG9-COOH 2576495-35-5
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-27