UCP1(D9D6X) Rabbit mAb
Source Reactivity Background References- Product Name
- UCP1(D9D6X) Rabbit mAb
- Chemical Name
- UCP1(D9D6X) Rabbit mAb
- Synonyms
- UCP1(D9D6X) Rabbit mAb
- CBNumber
- CB56280128
- Formula Weight
- 0
- MOL File
- Mol file
UCP1(D9D6X) Rabbit mAb Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Mouse
Background
Uncoupling protein 1 is a mitochondrial inner membrane transport protein that is primarily expressed in brown adipose tissue. UCP1 dissipates the pH gradient resulting from oxidative phosphorylation, which uncouples ATP synthesis from oxidative phosphorylation and leads to the release of heat energy. As a result, UCP1 plays an important role in thermogenesis. Research studies indicate that subcutaneous white adipose depots in mice contain beige adipocytes that express low levels of UCP1 protein. Additional studies show possible differences in thermogenesis in individuals carrying specific polymorphisms in the corresponding UCP1 gene. Related studies link UCP1 to the possible development of obesity and type 2 diabetes.
References
[1] Azzu, V. and Brand, M.D. (2010) Trends Biochem Sci 35, 298-307.
[2] Wu, J. et al. (2012) Cell 150, 366-76.
[3] Nagai, N. et al. (2003) J Clin Endocrinol Metab 88, 5661-7.
[4] Brondani, L.A. et al. (2012) Arq Bras Endocrinol Metabol 56, 215-25.
UCP1(D9D6X) Rabbit mAb Preparation Products And Raw materials
Raw materials
Preparation Products
UCP1(D9D6X) Rabbit mAb Suppliers
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