Source Reactivity Background References

UCP2 (D1O5V) Rabbit mAb

Source Reactivity Background References
Product Name
UCP2 (D1O5V) Rabbit mAb
Chemical Name
UCP2 (D1O5V) Rabbit mAb
Synonyms
UCP2 (D1O5V) Rabbit mAb
CBNumber
CB86280129
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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UCP2 (D1O5V) Rabbit mAb Chemical Properties,Usage,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

Uncoupling protein 2 is a mitochondrial inner membrane transport protein that is expressed in a wide range of tissues. UCP2 inhibits mitochondrial glucose oxidation and promotes glycolysis in human pluripotent stem cells. During early differentiation of hPSCs, the expression of UCP2 is repressed, which results in reduced glycolysis. This demonstrates a role for UCP2 in the metabolic reprogramming during differentiation of hPSCs. Overexpression of UCP2 in cancer cells stimulates oxidative phosphorylation in mitochondria and inhibits cell proliferation.

References

[1] Mailloux, R.J. et al. (2011) J Biol Chem 286, 21865-75.
[2] Zhang, J. et al. (2011) EMBO J 30, 4860-73.
[3] Esteves, P. et al. (2014) Cancer Res 74, 3971-82.

UCP2 (D1O5V) Rabbit mAb Preparation Products And Raw materials

Raw materials

Preparation Products

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UCP2 (D1O5V) Rabbit mAb Suppliers

Shanghai Universal Biotech Co.,Ltd
Tel
15921930842 15921930842
Email
yh-wang@univ-bio.com
Country
China
ProdList
25004
Advantage
58
Cell Signaling Technology Inc
Tel
21-80243558 86218024
Email
info@cellsignal.cn
Country
China
ProdList
6725
Advantage
58
Guangzhou Erxu Biotechnology Co., Ltd
Tel
13570209545
Country
CHINA
ProdList
104
Advantage
58
Gene Biotechnology International Trading (Shanghai) Co., Ltd. Guangzhou Branch
Tel
15107906345
Country
CHINA
ProdList
147
Advantage
58
Guangzhou Zhuanyan Biotechnology Co., Ltd.
Tel
18926165828
Country
CHINA
ProdList
198
Advantage
58
Beijing Boning Biotechnology Co., Ltd.
Tel
010-67500625 18210120938
Email
384669408@qq.com
Country
China
ProdList
195
Advantage
58