LICHROSORB(R) RP8 Property

Boiling point:

approximate 3,000℃

storage temp. 

Store at RT.

form 

Solid

color 

White

Water Solubility 

Soluble in hydrofluoric acid. Insoluble in water.

Sensitive 

Hygroscopic

Merck 

14,8493

Exposure limits

NIOSH: IDLH 3000 mg/m3; TWA 6 mg/m3

InChIKey

IJKVHSBPTUYDLN-UHFFFAOYSA-N

EPA Substance Registry System

Silica gel (63231-67-4)

Safety

WGK Germany 

3

RTECS 

VV7340000

F 

3

TSCA 

Yes

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

H360May damage fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

LICHROSORB(R) RP8 Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Excipient.

Uses

Silica gel, wide pore is mainly used for the dehydrated purification of the industrial gases, the clearance of the organic acids and high polymers in the insulative oil, the purification and separation of the medicines. It is also used in column chromatography without applied pressure (gravity pulled).

Definition

LICHROSORB(R) RP8 is an adsorbent consisting of amorphous silica produced by the reaction of sodium silicate with mineral acid.

Purification Methods

Before use as a drying agent, silica gel is heated in an oven, then cooled in a desiccator. Conditions in the literature range from heating at 110o for 15hours to 250o for 2-3hours. Silica gel has been purified by washing with hot acid (in one case successively with aqua regia, conc HNO3, then conc HCl; in another case it was digested overnight with hot conc H2SO4), followed by exhaustive washing with distilled water (one week in a Soxhlet apparatus has also been used), and prolonged oven drying. Alternatively, silica gel has been extracted with acetone until all soluble material was removed, then dried in a current of air, washed with distilled water and oven dried. Silica gel has also been washed successively with water, M HCl, water, and acetone, then activated at 110o for 15hours. Silicon monoxide [10097 -28 -6] M 44.1, m > 1700o, d 4 2.18. Purify the monoxide by sublimation in a porcelain tube in a furnace at 1250o (4hours) in a high vacuum (10-4mm) in a stream of N2. It is obtained as brownish black scales. [Schenk in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 696 1963.]