3-Bromo-6-chloro-2-methylpyridine

Product Name: 3-Bromo-6-chloro-2-methylpyridine
CAS No.: 132606-40-7
Chemical Name: 3-Bromo-6-chloro-2-methylpyridine
Synonyms: 3-BROMO-6-CHLORO-2-PICOLINE;2-Chloro-5-Bromo-6-Picoline;5-BROMO-2-CHLORO-6-PICOLINE;5-BROMO-2-CHLORO-6-METHYLPYRIDINE;3-BROMO-6-CHLORO-2-METHYL-PYRIDINE;2-methyl -5-bromo 6-chloro pyridine;Pyridine, 3-bromo-6-chloro-2-methyl-;3-Bromo-6-chloro-2-methylpyridine>3-Bromo-6-chloro-2-methylpyridine ISO 9001：2015 REACH
CBNumber: CB5673834
Molecular Formula: C6H5BrClN
Formula Weight: 206.47
MOL File: 132606-40-7.mol

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3-Bromo-6-chloro-2-methylpyridine Property

Melting point:: <40°C
Boiling point:: 80-84℃/2mm lit.
Density: 1.624±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Methanol
pka: -1.29±0.10(Predicted)
form: Liquid
color: White or Colorless to Light yellow
CAS DataBase Reference: 132606-40-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
RIDADR: UN 2811 6.1 / PGIII
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4405
Product name: 3-Bromo-6-chloro-2-methylpyridine
Purity: >97.0%(GC)
Packaging: 5g
Price: $163
Updated: 2025/07/31

TRC

Product number: B690628
Product name: 3-Bromo-6-chloro-2-methylpyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC55628
Product name: 2-Chloro-5-bromo-6-methylpyridine
Packaging: 2g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC55628
Product name: 2-Chloro-5-bromo-6-methylpyridine
Packaging: 5G
Price: $100
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-D-Z2
Product name: 3-Bromo-6-chloro-2-methylpyridine
Packaging: 5G
Price: $77
Updated: 2021/12/16

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3-Bromo-6-chloro-2-methylpyridine Chemical Properties,Usage,Production

Uses

3-Bromo-6-chloro-2-methylpyridine is an organic synthetic reagent for the preparation of difluoropyridine N-oxide and its 4-nitro derivative.

Synthesis

42753-71-9

132606-40-7

General procedure for the synthesis of 5-bromo-2-chloro-6-methylpyridine from 2-amino-5-bromo-6-methylpyridine: dichloromethane (900 mL) was added to a 2L three-necked round-bottomed flask, followed by the addition of 2-amino-6-methyl-5-bromopyridine (74.23 g, 0.39 mol), pyridine hydrochloride (139 g, 1.2 mol), sodium nitrite (83.26 g, 1.2 mol) and cuprous chloride (3.76 g, 5% w/w relative to the feedstock). The reaction mixture was cooled to 0-10 °C in an ice water bath. Hydrochloric acid (4.5 mL, 6% v/w vs. feedstock) was added slowly and stirred at 0-10 °C for 30 min. The cooling bath was removed and the mixture was continued to stir at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate (400 mL) and the organic and aqueous layers were separated and the aqueous layer was extracted with dichloromethane (100 mL). The organic layers were combined and concentrated to dryness. Hexane (750 mL) was added to the residue and stirred. The solid was collected by filtration, washed with hexane, and the filtrate was concentrated to dryness to afford the pure product 5-bromo-2-chloro-6-methylpyridine (61 g, 70% yield) in light yellow crystalline form.

References

[1] Patent: WO2007/22371, 2007, A2. Location in patent: Page/Page column 49
[2] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 2, p. 273 - 276
[3] Journal of Heterocyclic Chemistry, 2004, vol. 41, # 4, p. 569 - 574
[4] Patent: US2005/192310, 2005, A1. Location in patent: Page/Page column 36
[5] Patent: WO2011/28395, 2011, A1. Location in patent: Page/Page column 16

3-Bromo-6-chloro-2-methylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromo-6-chloro-2-methylpyridine Suppliers

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View Lastest Price from 3-Bromo-6-chloro-2-methylpyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Bromo-2-chloro-6-methylpyridine 132606-40-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2024-11-19

Henan Fengda Chemical Co., Ltd

Product: 3-Bromo-2-chloro-6-picoline 132606-40-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Henan Bao Enluo International TradeCo.，LTD

Product: 3-Bromo-6-chloro-2-methylpyridine 132606-40-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 50000tons
Release date: 2023-08-08

132606-40-7, 3-Bromo-6-chloro-2-methylpyridineRelated Search:

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3-Bromo-6-chloro-2-methylpyridine ISO 9001：2015 REACH

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132606-40-7

Heterocycle-Pyridine series

Pyridine series

Variety of halogenated heterocyclic series

blocks

Bromides

Pyridines

Pyridine

Halides