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4-Methoxy-2-nitrobenzoic acid

Product Name
4-Methoxy-2-nitrobenzoic acid
CAS No.
33844-21-2
Chemical Name
4-Methoxy-2-nitrobenzoic acid
Synonyms
RARECHEM AL BO 1421;2-Nitro-p-anisic Acid;2-NITRO-4-METHOXYBENZOIC ACID;4-METHOXY-2-NITROBENZOIC ACID;4-Methoxy-2-nitronbenzoic acid;Benzoic acid, 4-methoxy-2-nitro-;4-METHOXY-2-NITROBENZOIC ACID 98%;4-Carboxy-3-nitroanisole, 2-Nitro-p-anisic acid;4-Methoxy-2-nitrobenzoic acid ISO 9001:2015 REACH
CBNumber
CB5675333
Molecular Formula
C8H7NO5
Formula Weight
197.14
MOL File
33844-21-2.mol
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4-Methoxy-2-nitrobenzoic acid Property

Melting point:
196.5-200.5 °C (lit.)
Boiling point:
372.9±27.0 °C(Predicted)
Density 
1.430±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.46±0.25(Predicted)
color 
White to Light yellow to Light orange
CAS DataBase Reference
33844-21-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36
WGK Germany 
2
HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
638722
Product name
4-Methoxy-2-nitrobenzoic acid
Purity
97%
Packaging
1g
Price
$40
Updated
2023/06/20
Sigma-Aldrich
Product number
638722
Product name
4-Methoxy-2-nitrobenzoic acid
Purity
97%
Packaging
5g
Price
$156
Updated
2023/06/20
TCI Chemical
Product number
M2828
Product name
4-Methoxy-2-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$57
Updated
2025/07/31
TCI Chemical
Product number
M2828
Product name
4-Methoxy-2-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$171
Updated
2025/07/31
TRC
Product number
M327003
Product name
4-Methoxy-2-nitrobenzoic Acid
Packaging
1g
Price
$75
Updated
2021/12/16
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4-Methoxy-2-nitrobenzoic acid Chemical Properties,Usage,Production

Uses

4-Methoxy-2-nitrobenzoic acid can serve as a key step in chemical reactions for synthesizing certain drug molecules, or play a role in the synthesis of certain types of dyes, fragrances, and other chemicals.

Synthesis

17484-36-5

33844-21-2

Step 1: A mixed solution of 4-methyl-3-nitroanisole (3.6 g, 18 mmol) with potassium permanganate (10 g, 63 mmol) in 200 mL of water was refluxed for 24 hours. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble solids. The filtrate was acidified to pH 2 with 1 N hydrochloric acid and subsequently extracted with chloroform (3 x 50 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure and the precipitate precipitated was collected to give 4-methoxy-2-nitrobenzoic acid in 80% yield.

References

[1] Patent: US5665719, 1997, A
[2] Journal of Organic Chemistry, 2018, vol. 83, # 15, p. 8092 - 8103
[3] Chemische Berichte, 1918, vol. 51, p. 14
[4] Patent: US4781750, 1988, A

4-Methoxy-2-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxy-2-nitrobenzoic acid Suppliers

Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
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View Lastest Price from 4-Methoxy-2-nitrobenzoic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Methoxy-2-nitrobenzoic acid 33844-21-2
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Methoxy-2-nitrobenzoic acid 33844-21-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Shaanxi Dideu Medichem Co. Ltd
Product
4-Methoxy-2-nitrobenzoic acid 33844-21-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-07

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