ChemicalBook > CAS DataBase List > 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

Product Name: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS No.: 654-62-6
Chemical Name: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
Synonyms: I7C;NSC 44625;Trifluoromethyldisulfonamide;Bendroflumethiazide EP Impurity;Bendroflumethiazide EP Impurity A;Bendroflumethiazide impurity A CRS;4-Amino-6-(trifluoromethyl)benzene-;2,4-Disulfamyl-5-trifluoromethylaniline;4-Amino-6-(trifluoromethyl)benzene-1,3-d;3-(4-methylphenyl)sulfonylpropane-1,2-diol
CBNumber: CB5693012
Molecular Formula: C7H8F3N3O4S2
Formula Weight: 319.28
MOL File: 654-62-6.mol

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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Property

Melting point:: 241-246 °C
Boiling point:: 562.8±60.0 °C(Predicted)
Density: 1.743±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 9.14±0.60(Predicted)
form: Solid
color: White to Off-White
BRN: 1164542
InChI: InChI=1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17)
InChIKey: KRVABEGPNKGLOT-UHFFFAOYSA-N
SMILES: C1(S(N)(=O)=O)=C(C(F)(F)F)C=C(N)C(S(N)(=O)=O)=C1
CAS DataBase Reference: 654-62-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2935909550

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000564
Product name: Bendroflumethiazide impurity A
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 5 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1223005
Product name: 2,4-Disulfamyl-5-trifluoromethylaniline
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1300
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0000564
Product name: Bendroflumethiazide impurity A
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000564
Price: $153
Updated: 2024/03/01

TRC

Product number: D493580
Product name: 2,4-Disulfamyl-5-trifluoromethylaniline
Packaging: 1g
Price: $135
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA29652
Product name: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
Packaging: 5G
Price: $40
Updated: 2021/12/16

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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Chemical Properties,Usage,Production

Chemical Properties

Crystallizes. Melting point 242°C.

Uses

2,4-Disulfamyl-5-trifluoromethylaniline is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic.

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials

3-Nitrobenzotrifluoride Benzotrifluoride Benzotrichloride

Preparation Products

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View Lastest Price from 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide manufacturers

Career Henan Chemical Co

Product: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide 654-62-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-02-14

654-62-6, 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamideRelated Search:

3-Aminobenzenesulfonamide ALTRENOGEST 3-(Trifluoromethyl)benzoic acid Benzenesulfonamide Sulfanilamide Phenylmethylsulfonyl fluoride Glycine 2-(Trifluoromethyl)benzaldehyde 3-(Trifluoromethyl)benzaldehyde 4'-(Trifluoromethyl)acetophenone N,N-Dimethyl-1,4-phenylenediamine Tris(hydroxymethyl)aminomethane Benzene BENDROFLUMETHIAZIDE penflutizide flumethiazide HYDROFLUMETHIAZIDE 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

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I7C

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4-AMINO-6-(TRIFLUOROMETHYL)BENZENE-1,3-DISULFONAMIDE TECHN. 96%

5-amino-α,α,α-trifluorotoluene-2,4-disulphonamide

4-azanyl-6-(trifluoromethyl)benzene-1,3-disulfonamide

2,4-Disulfamyl-5-trifluoromethylaniline (30 mg)

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2-AMINO-4-TRIFLUOROMETHYL-1,5-BENZENEDISULFONAMIDE

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5-AMINO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE-2,4-DISULFONAMIDE

5-Amino-alpha,alpha,alpha-trifluorotoluene-2,4-disulphonamide

Trifluoromethyldisulfonamide

2,4-Disulfamyl-5-trifluoromethylaniline

Bendroflumethiazide impurity A CRS

4-Amino-6-(trifluoromethyl)benzene-

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (TFMSAA)

Bendroflumethiazide EP Impurity

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide ISO 9001：2015 REACH

4-Amino-6-(trifluoromethyl)benzene-1,3-d

4Amino6(trifluoromethyl)benzene1,3disulfonamide,4 Amino 6 (trifluoromethyl)benzene 1,3 disulfonamide

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide（TFDSA）（Intermediate of Bendroflumethiazide）

NSC 44625

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide, 10 mM in DMSO

654-62-6

C7H8F3N3O4S2

Building Blocks

Organic Building Blocks

Sulfonamides/Sulfinamides

Sulfur Compounds

A-AM

Bioactive Small Molecules

Building Blocks

Cell Biology

Chemical Synthesis

Organic Building Blocks

Sulfonamides/Sulfinamides

Sulfur Compounds