ChemicalBook > CAS DataBase List > NAC

NAC

Product Name: NAC
CAS No.: 154040-19-4
Chemical Name: NAC
Synonyms: NAC USP/EP/BP;61-95-α-Synuclein(human);α-Synuclein (61-95) (human);amyloid protein non-aβ component;AMYLOID PROTEIN NON-A BETA COMPONENT;EQVTNVGGAVVTGVTAVAQKTVEGAGSIIAAATGFV;Non-beta-Amyloid Component of Alzheimer’s Dise;NON-AB COMPONENT OF ALZHEIMER'S DISEASE AMYLOID;Non-Aβ Component of Alzheimer's Disease Amyloid;Amyloid Protein Non-Abeta Component >=80% (HPLC)
CBNumber: CB5697838
Molecular Formula: C141H235N39O49
Formula Weight: 3260.61
MOL File: 154040-19-4.mol

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NAC Property

Boiling point:: 2937.7±65.0 °C(predicted)
Density: 1.296±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp.: -20°C
form: solid
Sequence: H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2835
Product name: Amyloid Protein Non-Aβ Component
Purity: ≥80% (HPLC)
Packaging: 0.1mg
Price: $203
Updated: 2025/07/31

Biorbyt Ltd

Product number: orb372615
Product name: Non-Ab Component of Alzheimer's Disease Amyloid
Purity: > 95%
Packaging: 1mg
Price: $644.3
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372615
Product name: Non-Ab Component of Alzheimer's Disease Amyloid
Purity: > 95%
Packaging: 5mg
Price: $1368.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372615
Product name: Non-Ab Component of Alzheimer's Disease Amyloid
Purity: > 95%
Packaging: 10mg
Price: $2046.8
Updated: 2021/12/16

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NAC Chemical Properties,Usage,Production

Uses

α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].

Biochem/physiol Actions

Found in the insoluble core of amyloid plaque; forms fibrils via a nucleation-dependent polymerization mechanism

IC 50

α-synuclein

References

[1] Tabner BJ, et al. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med. 2002 Jun 1;32(11):1076-83. DOI:10.1016/s0891-5849(02)00801-8
[2] Emadi S, et al. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry. 2004 Mar 16;43(10):2871-8.

NAC Preparation Products And Raw materials

Raw materials

Preparation Products

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154040-19-4, NACRelated Search:

α-Synuclein (34-45) (human) α-Synuclein (45-54) (human) α-Synuclein (71-82) (human) α-Synuclein Binding Peptide L-Alanine, glycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-L-threonyl-L-alanyl-L-valyl- α-Synuclein (45-54) (human) trifluoroacetate salt L-Lysine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-leucyl-L-tyrosyl-L-valylglycyl-L-seryl-L-lysyl-L-threonyl- L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE PHENYLSELENOL TERT-BUTYL ISOCYANIDE Benzyl isocyanide Ethyl isocyanoacetate Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 2,4-PENTANEDIONE, SILVER DERIVATIVE

AMYLOID PROTEIN NON-A BETA COMPONENT

GLU-GLN-VAL-THR-ASN-VAL-GLY-GLY-ALA-VAL-VAL-THR-GLY-VAL-THR-ALA-VAL-ALA-GLN-LYS-THR-VAL-GLU-GLY-ALA-GLY-SER-ILE-ALA-ALA-ALA-THR-GLY-PHE-VAL

EQVTNVGGAVVTGVTAVAQKTVEGAGSIIAAATGFV

H-GLU-GLN-VAL-THR-ASN-VAL-GLY-GLY-ALA-VAL-VAL-THR-GLY-VAL-THR-ALA-VAL-ALA-GLN-LYS-THR-VAL-GLU-GLY-ALA-GLY-SER-ILE-ALA-ALA-ALA-THR-GLY-PHE-VAL-OH

H-GLU-GLN-VAL-THR-ASN-VAL-GLY-GLY-ALA-VAL-VAL-THR-GLY-VAL-THR-ALA-VAL-ALA-GLN-LYS-THR-VAL-GLU-GLY-ALA-GLY-SER-ILE-ILE-ALA-ALA-ALA-THR-GLY-PHE-VAL-OH

amyloid protein non-aβ component

NON-BETA-AMYLOID COMPONENT OF ALZHEIMER'S DISEASE

NON-BETA-AMYLOID COMPONENT OF ALZHEIMER'S DISEASE (NAC)

NON-AB COMPONENT OF ALZHEIMER'S DISEASE AMYLOID

NON-A-BETA COMPONENT OF ALZHEIMER'S DISEASE AMYLOID

Non-Aβ CoMponent of AlzheiMer's Disease AMyloid NAC

Non-Aβ Component of Alzheimer's Disease Amyloid

α-Synuclein (61-95) (human)

L-Valine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-L-threonyl-L-alanyl-L-valyl-L-alanyl-L-glutaminyl-L-lysyl-L-threonyl-L-valyl-L-α-glutamylglycyl-L-alanylglycyl-L-seryl-L-isoleucyl-L-alanyl-L-alanyl-L-alanyl-L-t...

Amyloid Protein Non-Abeta Component >=80% (HPLC)

α-Synuclein (61-95) (human) trifluoroacetate salt/NAC, α-Synuclein (61-95) (human)

61-95-α-Synuclein(human)

NAC USP/EP/BP

Non-Aβ CoMponent of AlzheiMer's Disease AMyloid NAC

α-Synuclein (61-95) (human) trifluoroacetate salt

Non-beta-Amyloid Component of Alzheimer’s Dise

154040-19-4

C141H235N39O49

Neurodegenerative Disease Peptides

Peptides

Other Amyloid Protein Fragments

Amino Acids and Peptides

Biochemicals and Reagents

BioChemical

peptide