4-Fluorobenzylamine

ChemicalBook > CAS DataBase List > 4-Fluorobenzylamine

4-Fluorobenzylamine

Product Name: 4-Fluorobenzylamine
CAS No.: 140-75-0
Chemical Name: 4-Fluorobenzylamine
Synonyms: (4-Fluorophenyl)methanamine;P-FLUOROBENZYLAMINE;Benzylamine, p-fluoro-;NSC 158269;AURORA KA-7685;P-flubenzylamine;AKOS BBS-00003618;RARECHEM AL BW 0026;4-FLUOROBENZYLAMINE;4-fluro benzylamine
CBNumber: CB5716902
Molecular Formula: C7H8FN
Formula Weight: 125.14
MOL File: 140-75-0.mol

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4-Fluorobenzylamine Property

Melting point:: 183 °C
Boiling point:: 183 °C (lit.)
Density: 1.095 g/mL at 25 °C (lit.)
refractive index: n20/D 1.512(lit.)
Flash point:: 152 °F
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 9.01±0.10(Predicted)
form: Liquid
Specific Gravity: 1.101.095
color: Clear colorless to light yellow
Water Solubility: Soluble in water.
Sensitive: Air Sensitive
BRN: 636501
InChIKey: IIFVWLUQBAIPMJ-UHFFFAOYSA-N
CAS DataBase Reference: 140-75-0(CAS DataBase Reference)
NIST Chemistry Reference: Benzenemethanamine, 4-fluoro-(140-75-0)
EPA Substance Registry System: Benzenemethanamine, 4-fluoro- (140-75-0)

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Safety

Hazard Codes: C,Xi
Risk Statements: 34-20/21/22
Safety Statements: 26-27-36/37/39-45-36/39
RIDADR: UN 2735 8/PG 2
WGK Germany: 3
F: 10-34
Hazard Note: Irritant
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29214980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 162493
Product name: 4-Fluorobenzylamine
Purity: 97%
Packaging: 5g
Price: $36.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 162493
Product name: 4-Fluorobenzylamine
Purity: 97%
Packaging: 25g
Price: $70
Updated: 2024/03/01

TCI Chemical

Product number: F0252
Product name: 4-Fluorobenzylamine
Purity: >98.0%(GC)
Packaging: 5g
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: F0252
Product name: 4-Fluorobenzylamine
Purity: >98.0%(GC)
Packaging: 25g
Price: $56
Updated: 2024/03/01

Alfa Aesar

Product number: A15486
Product name: 4-Fluorobenzylamine, 98+%
Packaging: 10g
Price: $31.65
Updated: 2024/03/01

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4-Fluorobenzylamine Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liquid.

Uses

4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.

General Description

[¹⁸F]4-fluorobenzylamine reacts with the α- and γ-carboxyl groups of folic acid to yield ¹⁸F-labeled folate. It is an important building block for the synthesis of ¹⁸F-labeled compounds.

Synthesis

In a 100ml reaction flask, add 25.5g (0.1mol) of N-(4-fluorobenzyl)phthalimide and 25ml of absolute ethanol, then add 6.3g (0.1mol) of 80% hydrazine hydrate solution, and heat Reflux 0.5g. Excessive hydrochloric acid was added to decompose the precipitated white precipitate, after cooling, an appropriate amount of water was added to stir, and suction filtered. The filtrate was neutralized with NaOH solution, extracted with ether, and the ether extract was dried, evaporated to remove ether, distilled under reduced pressure, and collected fractions at 44-46°C (67kPa) to obtain 7.1 g of 4-fluorobenzylamine, with a yield of 56.5%.

4-Fluorobenzylamine Preparation Products And Raw materials

Raw materials

Phthalimide 4-fluorobenzene

Preparation Products

Flupirtine 4-FLUOROBENZYL ISOCYANATE

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View Lastest Price from 4-Fluorobenzylamine manufacturers

Anhui Dexinjia Biopharm Co., Ltd

Product: 4-Fluorobenzylamine 140-75-0
Price: US $10.00-150.00/kg
Min. Order: 1kg
Purity: NLT98%
Supply Ability: 2 ton per month
Release date: 2023-04-02

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Fluorobenzylamine 140-75-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2019-12-31

Honest Joy Holdings Limited

Product: 4-Fluorobenzylamine 140-75-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.3%
Supply Ability: 100 tons
Release date: 2022-01-26

140-75-0, 4-FluorobenzylamineRelated Search:

4-Fluorobenzamide Trimethoprim Methylamine hydrochloride Meglumine Ethyl nicotinate Phenoxybenzamine hydrochloride Trimethylamine N-Methylbenzylamine 4-Fluorobenzoic acid Dibenzylamine Benzylamine 2,4-Difluorobenzylamine 4-Fluorothiophenol 4-Fluoromandelic acid Methyl 4-fluorobenzoate Ethyl 4-fluorobenzoate 4-Fluorobenzonitrile 4-Fluorobenzaldehyde

4-Fluorobenzylamine ,99%

4-FluorobenzylaMine, 97% 25GR

p-FluorobenzeneMethanaMine

4-FLUOROBENZYLAMINE FOR SYNTHESIS

4-FluorobenzylaMine0.99

(4-Fluorophenyl)methanamine

4-fluoro-benzenemethanamin

Benzylamine, p-fluoro-

P-FLUOROBENZYLAMINE

RARECHEM AL BW 0026

4- fluorinebenzyl aMine

The fluorine benzylaMine

4-FLUOROBENZYLAMINE

AKOS BBS-00003618

LABOTEST-BB LTBB000702

AURORA KA-7685

Flupirtine Impurity J

4-fluoroBenzenemethanamine

4-FLUOROBENZYLAMINE, 97+%

Para Fluorobenzyamine

Benzenemethanamine, 4-fluoro-

4-Fluorobenzylamine 98%

4-FLUOROBENZYLAMINE 98+%

[(4-Fluorophenyl)methyl]amine

1-(4-Fluorophenyl)methanamine

NSC 158269

4-Fluorobenzylamine&gt

4-fluro benzylamine

4-Fluorobenzylamine ISO 9001：2015 REACH

4-Fluorobenzylamine extrapure, 99%

Glimepiride Impurity 39 Hydrochloride

P-flubenzylamine

140-75-0

C7H5FN

Nitrogen Compounds

Organic Building Blocks

Amines

Building Blocks

Anilines, Aromatic Amines and Nitro Compounds

Amines

Aromatics

Amine

Nitrogen Compounds

fine chemicals

bc0001

john's