Phthalazine

ChemicalBook > CAS DataBase List > Phthalazine

Product Name: Phthalazine
CAS No.: 253-52-1
Chemical Name: Phthalazine
Synonyms: PHZ;PHTHALAZINE;β-Phenodiazine;Phthalazine>Phthalazine~99%;Phthalazine,98%;2,3-Benzodiazin;2,3-BENZODIAZINE;beta-Phenodiazine;BENZO[D]PYRIDAZINE
CBNumber: CB5734171
Molecular Formula: C8H6N2
Formula Weight: 130.15
MOL File: 253-52-1.mol

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Phthalazine Property

Melting point:: 89-92 °C(lit.)
Boiling point:: 189 °C29 mm Hg(lit.)
Density: 1.1509 (rough estimate)
refractive index: 1.6231 (estimate)
Flash point:: 178-180°C/15mm
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Crystalline Powder
pka: 3.47(at 20℃)
color: Slightly brown to beige
Water Solubility: Soluble in water, methanol, chloroform.
Merck: 14,7370
BRN: 109240
CAS DataBase Reference: 253-52-1(CAS DataBase Reference)
NIST Chemistry Reference: Phthalazine(253-52-1)
EPA Substance Registry System: Phthalazine (253-52-1)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-68
Safety Statements: 24/25-37/39-36-26-36/37/39
WGK Germany: 3
TSCA: Yes
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H341Suspected of causing genetic defects

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P38706
Product name: Phthalazine
Purity: 98%
Packaging: 1g
Price: $46.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1535959
Product name: Phthalazine
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 20mg
Price: $1150
Updated: 2024/03/01

TCI Chemical

Product number: P0694
Product name: Phthalazine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $33
Updated: 2024/03/01

TCI Chemical

Product number: P0694
Product name: Phthalazine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $101
Updated: 2024/03/01

Alfa Aesar

Product number: A12270
Product name: Phthalazine, 98%
Packaging: 5g
Price: $65.65
Updated: 2024/03/01

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Phthalazine Chemical Properties,Usage,Production

Chemical Properties

SLIGHTLY BROWN TO BEIGE CRYSTALLINE POWDER

Uses

Phthalazine derivatives including copper and platinum complexes were induce the apoptosis in breast cancer cell lines and renal hyperemia.

Uses

Phthalazine is a heterocyclic organic compound isomeric with quinoxaline, cinnoline and quinazoline. Aminophthalazine compounds serve as effective phosphodiesterase (PDE) inhibitors.

Definition

ChEBI: An azaarene that is the 2,3-diaza analogue of naphthalene. The parent of the class of phthalazines.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 2, p. 206, 1965 DOI: 10.1002/jhet.5570020219

Purification Methods

Phthalazine crystallises from diethyl ether or *benzene, and sublimes under a vacuum. The hydrochloride forms needles from EtOH with m 235-236o(dec) and the picrate has m 208-210o. [Armarego J Appl Chem 11 70 1961, Beilstein 23 H 174, 23 III/IV 1233.]

Phthalazine Preparation Products And Raw materials

Raw materials

Preparation Products

Ophthazin Cadralazine 1-CHLOROPHTHALAZINE Hyaluronidase

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View Lastest Price from Phthalazine manufacturers

Career Henan Chemical Co

Product: Phthalazine 253-52-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-06-28

253-52-1, PhthalazineRelated Search:

DBU Phthalylsulfathiazole Phthalhydrazide Phthalic anhydride Phthaloyl amlodipine Ophthazin Todralazine hydrochloride (DHQ)2PHAL 1,4-Dichlorophthalazine 1-BENZYL-4-CHLOROPHTHALAZINE 1-CHLOROPHTHALAZINE Dihydralazine sulphate 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE METHYL 2-[(4-BENZYL-1-PHTHALAZINYL)SULFANYL]ACETATE Phthalazine 1-BENZYL-4-[(4-CHLOROBENZYL)SULFANYL]PHTHALAZINE 1-BENZYL-4-(4-METHOXYPHENOXY)PHTHALAZINE 4-[(4-BENZYL-1-PHTHALAZINYL)OXY]BENZENECARBONITRILE

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PHZ

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Phthalazine,98%

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Phthalazine, 98% 10GR

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Hydralazine Hydrochloride Impurity Ⅰ：Phthalazine

Phthalazine (6CI, 7CI, 8CI, 9CI, ACI)

*Furosemide Impurity 32

Hydralizine EP impurity-D

Phthalazine, ≥ 98.0%

253-52-1

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