ChemicalBook > CAS DataBase List > Phthalazine

Phthalazine

Product Name
Phthalazine
CAS No.
253-52-1
Chemical Name
Phthalazine
Synonyms
PHZ;PHTHALAZINE;β-Phenodiazine;Phthalazine>Phthalazine~99%;Phthalazine,98%;2,3-Benzodiazin;2,3-BENZODIAZINE;beta-Phenodiazine;BENZO[D]PYRIDAZINE
CBNumber
CB5734171
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
253-52-1.mol
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Phthalazine Property

Melting point:
89-92 °C(lit.)
Boiling point:
189 °C29 mm Hg(lit.)
Density 
1.1509 (rough estimate)
refractive index 
1.6231 (estimate)
Flash point:
178-180°C/15mm
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
3.47(at 20℃)
color 
Slightly brown to beige
Water Solubility 
Soluble in water, methanol, chloroform.
Merck 
14,7370
BRN 
109240
CAS DataBase Reference
253-52-1(CAS DataBase Reference)
NIST Chemistry Reference
Phthalazine(253-52-1)
EPA Substance Registry System
Phthalazine (253-52-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-68
Safety Statements 
24/25-37/39-36-26-36/37/39
WGK Germany 
3
TSCA 
Yes
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P38706
Product name
Phthalazine
Purity
98%
Packaging
1g
Price
$46.3
Updated
2024/03/01
Sigma-Aldrich
Product number
1535959
Product name
Phthalazine
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
20mg
Price
$1150
Updated
2024/03/01
TCI Chemical
Product number
P0694
Product name
Phthalazine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
P0694
Product name
Phthalazine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$101
Updated
2024/03/01
Alfa Aesar
Product number
A12270
Product name
Phthalazine, 98%
Packaging
5g
Price
$65.65
Updated
2024/03/01
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Phthalazine Chemical Properties,Usage,Production

Chemical Properties

SLIGHTLY BROWN TO BEIGE CRYSTALLINE POWDER

Uses

Phthalazine derivatives including copper and platinum complexes were induce the apoptosis in breast cancer cell lines and renal hyperemia.

Uses

Phthalazine is a heterocyclic organic compound isomeric with quinoxaline, cinnoline and quinazoline. Aminophthalazine compounds serve as effective phosphodiesterase (PDE) inhibitors.

Definition

ChEBI: Phthalazine is an azaarene that is the 2,3-diaza analogue of naphthalene. The parent of the class of phthalazines. It is a mancude organic heterobicyclic parent, a member of phthalazines, an azaarene and an ortho-fused heteroarene.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 2, p. 206, 1965 DOI: 10.1002/jhet.5570020219

Purification Methods

Phthalazine crystallises from diethyl ether or *benzene, and sublimes under a vacuum. The hydrochloride forms needles from EtOH with m 235-236o(dec) and the picrate has m 208-210o. [Armarego J Appl Chem 11 70 1961, Beilstein 23 H 174, 23 III/IV 1233.]

Phthalazine Preparation Products And Raw materials

Raw materials

Preparation Products

Ophthazin Cadralazine 1-CHLOROPHTHALAZINE Hyaluronidase
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Phthalazine Suppliers

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View Lastest Price from Phthalazine manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
Phthalazine 253-52-1
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
5 MTs
Release date
2024-05-11
Career Henan Chemical Co
Product
Phthalazine 253-52-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-06-28

253-52-1, PhthalazineRelated Search:

DBU Phthalylsulfathiazole Phthalhydrazide Phthalic anhydride Phthaloyl amlodipine Ophthazin Todralazine hydrochloride (DHQ)2PHAL 1,4-Dichlorophthalazine 1-BENZYL-4-CHLOROPHTHALAZINE 1-CHLOROPHTHALAZINE Dihydralazine sulphate 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE METHYL 2-[(4-BENZYL-1-PHTHALAZINYL)SULFANYL]ACETATE Phthalazine 1-BENZYL-4-[(4-CHLOROBENZYL)SULFANYL]PHTHALAZINE 1-BENZYL-4-(4-METHOXYPHENOXY)PHTHALAZINE 4-[(4-BENZYL-1-PHTHALAZINYL)OXY]BENZENECARBONITRILE

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