Todralazine hydrochloride
- Product Name
- Todralazine hydrochloride
- CAS No.
- 3778-76-5
- Chemical Name
- Todralazine hydrochloride
- Synonyms
- binazin;binazine;apirachol;ECARAZINE;Apiracohl;Hydrapron;TODRALAZINE HCL;621-bthydrochloride;ECARAZINE HYDROCHLORIDE;TODRALAZINE HYDROCHLORIDE
- CBNumber
- CB7312164
- Molecular Formula
- C11H13ClN4O2
- Formula Weight
- 268.7
- MOL File
- 3778-76-5.mol
Todralazine hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): slightly
- form
- A crystalline solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 20893
- Product name
- Todralazine (hydrochloride)
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $85
- Updated
- 2024/03/01
- Product number
- 20893
- Product name
- Todralazine (hydrochloride)
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $158
- Updated
- 2024/03/01
- Product number
- 20893
- Product name
- Todralazine (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $299
- Updated
- 2024/03/01
- Product number
- O389
- Product name
- TodralazineHCl
- Packaging
- 1g
- Price
- $430
- Updated
- 2021/12/16
- Product number
- CS-0098222
- Product name
- Todralazinehydrochloride
- Purity
- 98.17%
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
Todralazine hydrochloride Chemical Properties,Usage,Production
Originator
Prorazin,Teisan
Uses
Todralazine Hydrochloride is an antihypertensive agent for research use. Vasodilator.
Uses
Antihypertensor
Manufacturing Process
A suspension of 13 g of hydrazinophthalazine in 500 ml of anhydrous ethanol
is cooled, under agitation to a temperature of -10°C. To the suspension is
added dropwise within 30 min a solution of 4.5 g of ethyl chlorocarbonate in
150 ml of anhydrous ethanol and the reaction mass is agitated for about 2
hours, maintaining a temperature of -10°C. The temperature is then raised to
about 20°C and stirring is continued for 2 hours, whereupon heating is applied
and boiling is maintained for 15 min. After cooling, the separated 1-
hydrazinophthalazine hydrochloride is filtered and washed with anhydrous
ethanol.
The filtrate is evaporated to a dry state under decreased pressure at a
temperature of below 50°C. The residue in a quantity of 8.5 g is dissolved in a
boiling solution of 3 ml of concentrated hydrochloric acid in 15 ml of water,
and after adding 5 ml of 90%-ethanol the solution is cooled to a temperature
of below 0°C.
The separated 1-carboethoxyhydrazinophthalazine hydrochloride is filtered and
washed with anhydrous ethanol. 11.5 g of a raw product are obtained which
for the purpose of purification are dissolved in 15 ml of boiling water with an
addition of 10 ml of 96%-ethanol and after cooling to below 0°C, the pure 1-
carboethoxyhydrazinophthalazine hydrochloride is filtered. 9.8 g of the are
obtained.
Therapeutic Function
Antihypertensive
Todralazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Todralazine hydrochloride Suppliers
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View Lastest Price from Todralazine hydrochloride manufacturers
- Product
- Todralazine hydrochloride 3778-76-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-07-15