ChemicalBook > CAS DataBase List > Budralazine

Budralazine

Product Name
Budralazine
CAS No.
36798-79-5
Chemical Name
Budralazine
Synonyms
PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
CBNumber
CB4282099
Molecular Formula
C14H16N4
Formula Weight
240.3
MOL File
36798-79-5.mol
More
Less

Budralazine Property

Melting point:
183-185 °C(lit.)
Boiling point:
373.02°C (rough estimate)
Density 
1.1506 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
9.54±0.70(Predicted)
color 
Light Yellow to Yellow
Stability:
Light Sensitive
CAS DataBase Reference
36798-79-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
TH9185000
Toxicity
LD50 in mice, rats (mg/kg): 1820, 620 orally; 4020, 3570 i.p. (Onodera)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
B689515
Product name
Budralazine
Packaging
50mg
Price
$185
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001776
Product name
BUDRALAZINE
Purity
95.00%
Packaging
50MG
Price
$329.7
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18537
Product name
Budralazine
Packaging
25mg
Price
$1500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001776
Product name
BUDRALAZINE
Purity
95.00%
Packaging
500MG
Price
$1963.5
Updated
2021/12/16
More
Less

Budralazine Chemical Properties,Usage,Production

Description

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

Originator

Daiichi (Japan)

Uses

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Definition

ChEBI: Budralazine is a member of phthalazines.

Manufacturing Process

A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

brand name

BUTERAZINE

Therapeutic Function

Antihypertensive

Budralazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Budralazine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55827
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10326
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
29016
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
9231
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49390
Advantage
58
Hebei mo Jin biotechnology co., ltd
Tel
13288715578
Email
angelia@hbmojin.com
Country
China
ProdList
1759
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
More
Less

View Lastest Price from Budralazine manufacturers

Dideu Industries Group Limited
Product
Budralazine 36798-79-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-10
Shaanxi Dideu Medichem Co. Ltd
Product
Budralazine 36798-79-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-09

36798-79-5, BudralazineRelated Search:


  • PTLZ
  • 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE
  • 1,2-DIHYDROPHTHALAZIN-1-ONE
  • 1,2H-PHTHALAZONE
  • 1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
  • DIHYDROOXOPHTHALAZINE
  • BUDRALAZINE
  • 1-[2-(1,3-Dimethyl-2-buten-1-ylidene)hydrazino]phthalazine
  • 4-Methyl-3-penten-2-one (phthalazin-1-yl)hydrazone
  • Buterazine
  • DJ-1461
  • 1(2H)-Phthalazinone (1,3-DiMethyl-2-butenylidene)hydrazone
  • 4-Methyl-3-Penten-2-one 2-(1-phthalazinyl)hydrazone
  • Budralazine USP/EP/BP
  • 3-Penten-2-one, 4-methyl-, 2-(1-phthalazinyl)hydrazone
  • Butrazine
  • 36798-79-5
  • Pyridazines
  • Heterocyclic Building Blocks
  • Building Blocks