Budralazine
- Product Name
- Budralazine
- CAS No.
- 36798-79-5
- Chemical Name
- Budralazine
- Synonyms
- PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
- CBNumber
- CB4282099
- Molecular Formula
- C14H16N4
- Formula Weight
- 240.3
- MOL File
- 36798-79-5.mol
Budralazine Property
- Melting point:
- 183-185 °C(lit.)
- Boiling point:
- 373.02°C (rough estimate)
- Density
- 1.1506 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 9.54±0.70(Predicted)
- color
- Light Yellow to Yellow
- Stability:
- Light Sensitive
- CAS DataBase Reference
- 36798-79-5(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- B689515
- Product name
- Budralazine
- Packaging
- 50mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- API0001776
- Product name
- BUDRALAZINE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $329.7
- Updated
- 2021/12/16
- Product number
- 18537
- Product name
- Budralazine
- Packaging
- 25mg
- Price
- $1500
- Updated
- 2021/12/16
- Product number
- API0001776
- Product name
- BUDRALAZINE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1963.5
- Updated
- 2021/12/16
Budralazine Chemical Properties,Usage,Production
Description
Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.
Originator
Daiichi (Japan)
Uses
Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.
Definition
ChEBI: Budralazine is a member of phthalazines.
Manufacturing Process
A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.
brand name
BUTERAZINE
Therapeutic Function
Antihypertensive
Budralazine Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from Budralazine manufacturers
- Product
- Budralazine 36798-79-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-10
- Product
- Budralazine 36798-79-5
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-09