Budralazine

Product Name: Budralazine
CAS No.: 36798-79-5
Chemical Name: Budralazine
Synonyms: PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
CBNumber: CB4282099
Molecular Formula: C14H16N4
Formula Weight: 240.3
MOL File: 36798-79-5.mol

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Budralazine Property

Melting point:: 183-185 °C(lit.)
Boiling point:: 373.02°C (rough estimate)
Density: 1.1506 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 9.54±0.70(Predicted)
color: Light Yellow to Yellow
Stability:: Light Sensitive
CAS DataBase Reference: 36798-79-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TH9185000
Toxicity: LD50 in mice, rats (mg/kg): 1820, 620 orally; 4020, 3570 i.p. (Onodera)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B689515
Product name: Budralazine
Packaging: 50mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001776
Product name: BUDRALAZINE
Purity: 95.00%
Packaging: 50MG
Price: $329.7
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18537
Product name: Budralazine
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001776
Product name: BUDRALAZINE
Purity: 95.00%
Packaging: 500MG
Price: $1963.5
Updated: 2021/12/16

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Budralazine Chemical Properties,Usage,Production

Description

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

Originator

Daiichi (Japan)

Uses

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Definition

ChEBI: Budralazine is a member of phthalazines.

Manufacturing Process

A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

brand name

BUTERAZINE

Therapeutic Function

Antihypertensive

Budralazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Budralazine Suppliers

Canada 1 China 29 Czech 1 Europe 1 France 1 India 2 Japan 2 Ukraine 1 United Kingdom 6 United States 18 Global 62

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View Lastest Price from Budralazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Budralazine 36798-79-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-09

36798-79-5, BudralazineRelated Search:

Maleic acid 2,6-DIMETHYLNAPHTHALENE DBU 1,2-Dimethylhydrazine Dihydrochloride ETHANE Dimethyl phthalate Dimethyl sulfide Dimethyl ether Polybutene CIS-BUTENEDIOIC ANHYDRIDE Fumaric acid Dimethyl fumarate Dimethyl sulfoxide N,N-Dimethylformamide 3-BUTENE-1,2-DIOL Phthalazine Chrysene 1,2H-PHTHALAZONE,PHTHALAZONE

PTLZ

1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE

1,2-DIHYDROPHTHALAZIN-1-ONE

1,2H-PHTHALAZONE

1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE

DIHYDROOXOPHTHALAZINE

BUDRALAZINE

1-[2-(1,3-Dimethyl-2-buten-1-ylidene)hydrazino]phthalazine

4-Methyl-3-penten-2-one (phthalazin-1-yl)hydrazone

Buterazine

DJ-1461

1(2H)-Phthalazinone (1,3-DiMethyl-2-butenylidene)hydrazone

4-Methyl-3-Penten-2-one 2-(1-phthalazinyl)hydrazone

Budralazine USP/EP/BP

3-Penten-2-one, 4-methyl-, 2-(1-phthalazinyl)hydrazone

Butrazine

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