ChemicalBook > CAS DataBase List > 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

Product Name
6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
CAS No.
38923-08-9
Chemical Name
6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Synonyms
Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate;ethyl 6-nitroH-imidazo[1,2-a]pyridine-2-carboxylate;6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;6-nitroimidazo[1,2-α]pyridine-2-carboxylic acid ethyl ester;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-nitro-, ethyl ester;Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate, CAS 38923-08-9;6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%
CBNumber
CB5738199
Molecular Formula
C10H9N3O4
Formula Weight
235.2
MOL File
38923-08-9.mol
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6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Property

Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
0.18±0.50(Predicted)
Appearance
Off-white to yellow Solid
InChI
InChI=1S/C10H9N3O4/c1-2-17-10(14)8-6-12-5-7(13(15)16)3-4-9(12)11-8/h3-6H,2H2,1H3
InChIKey
XOXFLWMGZPJKAF-UHFFFAOYSA-N
SMILES
C12=NC(C(OCC)=O)=CN1C=C([N+]([O-])=O)C=C2
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0037532
Product name
Ethyl6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Packaging
5g
Price
$135
Updated
2021/12/16
Matrix Scientific
Product number
056342
Product name
Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Purity
>95%
Packaging
500mg
Price
$181
Updated
2021/12/16
Matrix Scientific
Product number
056342
Product name
Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Purity
>95%
Packaging
1g
Price
$228
Updated
2021/12/16
AK Scientific
Product number
W5941
Product name
Ethyl6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Packaging
25g
Price
$451
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0960341
Product name
6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Purity
95.00%
Packaging
1G
Price
$461
Updated
2021/12/16
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6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

4214-76-0

70-23-5

38923-08-9

The reaction was carried out at reflux for 16 hours with 2-amino-5-nitropyridine (1.5 g, 10.80 mmol) and ethyl 3-bromopyruvate (1.6 mL, 13.00 mmol) dissolved in ethanol (15.0 mL). After completion of the reaction, the reaction mixture was filtered and a light yellow solid was collected. The filtrate was extracted with ethyl acetate and washed sequentially with saturated aqueous sodium bicarbonate and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography (silica gel, n-hexane: ethyl acetate = 2:1) to afford ethyl 6-nitroimidazo[1,2-A]pyridine-2-carboxylate (2.3 g, 90% yield) as a yellow solid.LC/MS ESI(+): m/z 236 [M + H]+. 1H NMR (300 MHz, CDCl3) δ: 9.30 (s, 1H), 8.38 (s, 1H), 8.06 (d, 1H, J = 10.0 Hz), 7.84 (d, 1H, J = 10.4 Hz), 4.50 (q, 2H, J = 7.2 Hz), 1.46 (t, 3H, J = 7.2 Hz).

References

[1] Patent: WO2014/196793, 2014, A1. Location in patent: Page/Page column 64; 65
[2] Molecular Pharmaceutics, 2015, vol. 12, # 6, p. 1813 - 1835
[3] Patent: WO2015/185142, 2015, A1. Location in patent: Page/Page column 20
[4] Patent: WO2008/100423, 2008, A1. Location in patent: Page/Page column 111
[5] Patent: EP1657242, 2006, A1. Location in patent: Page/Page column 27

6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Suppliers

China 58 France 1 India 2 United Kingdom 1 United States 15 Global 77
BoroChem SAS
Tel
--
Fax
--
Email
info@borochem.fr
Country
France
ProdList
852
Advantage
46
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View Lastest Price from 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 38923-08-9
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-02

38923-08-9, 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTERRelated Search:

6-Nitroimidazo[1,2-a]pyridine-2-carboxylic acid 6-Nitrooxidole 6-nitrothiazolo[4,5-b]pyridin-2-aMine 6-NITRO-ISOINDOLIN-1-ONE 6-NITROPYRIDINE-2-CARBOXYLIC ACID 6-NITROISOQUINOLINE 5-HYDROXY-2-NITROPYRIDINE 6-NITROQUINOXALINE 6-NITRO INDAZOLE-3-CARBOXALDEHYDE 6-nitrobenzo[d]isoxazol-3-amine Methyl 6-nitronicotinate 6-NITROIMIDAZO[1,2-A]PYRIDINE Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Imidazo[1,2-a]pyridin-6-amine (9CI) 2-Methyl-6-nitroimidazo[1,2-a]pyridine 3-IODO-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

  • 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
  • 6-nitroimidazo[1,2-α]pyridine-2-carboxylic acid ethyl ester
  • 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%
  • Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-nitro-, ethyl ester
  • ethyl 6-nitroH-imidazo[1,2-a]pyridine-2-carboxylate
  • Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate, CAS 38923-08-9
  • 38923-08-9
  • Heterocycle-Pyridine series