ChemicalBook > CAS DataBase List > 6-(Z-AMINO)-1-HEXANOL

6-(Z-AMINO)-1-HEXANOL

Product Name
6-(Z-AMINO)-1-HEXANOL
CAS No.
17996-12-2
Chemical Name
6-(Z-AMINO)-1-HEXANOL
Synonyms
Z-ACP(6)-OL;Z-NH-(CH2)6-OH;Carbamic acid, (6-hy;6-(2-Amino)-1-hexanol;6-(Z-AMINO)-1-HEXANOL;CBZ-6-AMINO-HEXAN-1-OL;Benzyl (6-hydroxyhexyl);6-(Cbz-amino)-1-hexanol;N-CBZ-6-AMINO-HEXAN-1-OL;N-Cbz-6-hydroxyhexylamine
CBNumber
CB5752618
Molecular Formula
C14H21NO3
Formula Weight
251.32
MOL File
17996-12-2.mol
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6-(Z-AMINO)-1-HEXANOL Property

Melting point:
80-82 °C
Boiling point:
419.6±38.0 °C(Predicted)
Density 
1.087±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.71±0.46(Predicted)
form 
powder
Appearance
White to off-white Solid
BRN 
2121987
InChI
InChI=1S/C14H21NO3/c16-11-7-2-1-6-10-15-14(17)18-12-13-8-4-3-5-9-13/h3-5,8-9,16H,1-2,6-7,10-12H2,(H,15,17)
InChIKey
JMOQYRXPJQMWRQ-UHFFFAOYSA-N
SMILES
C(OCC1=CC=CC=C1)(=O)NCCCCCCO
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
95895
Product name
6-(Z-Amino)-1-hexanol
Purity
≥98.0%
Packaging
1g
Price
$130
Updated
2023/06/20
TCI Chemical
Product number
B6075
Product name
6-(N-Benzyloxycarbonylamino)-1-hexanol
Packaging
1G
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
B6075
Product name
6-(N-Benzyloxycarbonylamino)-1-hexanol
Packaging
5G
Price
$213
Updated
2025/07/31
Biosynth Carbosynth
Product number
FC45807
Product name
Cbz-6-aminohexan-1-ol
Packaging
25g
Price
$325
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC45807
Product name
Cbz-6-aminohexan-1-ol
Packaging
2g
Price
$80
Updated
2021/12/16
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6-(Z-AMINO)-1-HEXANOL Chemical Properties,Usage,Production

reaction suitability

reagent type: cross-linking reagent

Synthesis

4048-33-3

501-53-1

17996-12-2

General procedure: 6-amino-1-hexanol (5.0 g, 42.7 mmol) was dissolved in a solvent mixture of tetrahydrofuran (50 mL) and water (15 mL), and benzyl chloroformate (7.3 mL, 51.2 mmol) was added slowly and dropwise at 0°C. The pH of the reaction solution was adjusted to 8-9 by adding 1N sodium hydroxide solution (12 mL). Under the condition of maintaining the temperature of the reaction system at 0 °C, 1N sodium hydroxide solution (12 mL) was slowly added to adjust the pH of the reaction solution to 8-9, a process that took about 30 min. Subsequently, the reaction mixture was continued to be stirred at room temperature for 30 minutes. Upon completion of the reaction, the reaction was extracted with ether (30 mL x 3), the organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting crude product was recrystallized by solvent recrystallization of a mixture of dichloromethane and hexane to afford N-Cbz-6-amino-1-hexanol as a white crystalline solid (3.85 g, 90% yield). The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3): δ7.34 (m, 5H, Ar-H), 5.07 (s, 2H, PhCH2), 4.73 (br, 1H, NH), 3.61 (t, J=6.4Hz, 2H, CH2O), 3.16 (dt, J=6.8,6.8 Hz, 2H, NCH2), 1.61-1.32 (m, 8H, CH2); 13C NMR (100 MHz, CDCl3): δ 156.4 (C=O), 136.6,128.5,128.1 (Ar-C), 66.6 (PhCH2), 62.7 (CH2OH), 40.9 (NHCH2), 32.5 ( CH2CH2OH), 29.9 (NHCH2CH2), 26.3 (CH2CH2CH2OH), 25.3 (NCH2CH2CH2).

References

[1] Organic and Biomolecular Chemistry, 2016, vol. 14, # 41, p. 9716 - 9719
[2] Canadian Journal of Chemistry, 1988, vol. 66, p. 1651 - 1655
[3] Chemistry - An Asian Journal, 2011, vol. 6, # 7, p. 1800 - 1810
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 4, p. 912 - 921
[5] Organic and Biomolecular Chemistry, 2018, vol. 16, # 8, p. 1343 - 1350

6-(Z-AMINO)-1-HEXANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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6-(Z-AMINO)-1-HEXANOL Suppliers

Americas 1 China 72 Europe 1 India 3 Japan 2 Switzerland 1 United Kingdom 2 United States 11 Global 93
Carbosynth
Tel
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Fax
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Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
CARBONE SCIENTIFIC CO.,LTD
Tel
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Fax
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Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from 6-(Z-AMINO)-1-HEXANOL manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
6-(Z-AMINO)-1-HEXANOL 17996-12-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-07-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Benzyl (6-Hydroxyhexyl)carbamate 17996-12-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-21
Hebei Chuanghai Biotechnology Co., Ltd
Product
6-(Z-AMINO)-1-HEXANOL 17996-12-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29

17996-12-2, 6-(Z-AMINO)-1-HEXANOLRelated Search:

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