6-Amino-1-hexanol

Product Name: 6-Amino-1-hexanol
CAS No.: 4048-33-3
Chemical Name: 6-Amino-1-hexanol
Synonyms: 6-Aminohexan-1-ol;6-AMINOHEXANOL;1-Hexanol, 6-amino-;H-ACP-OL;H-AHX-OL;H-ACP(6)-OL;Hexanolamine;NH2-(CH2)6-OH;6-Hexanolamine;6-amino-hexano
CBNumber: CB5104017
Molecular Formula: C6H15NO
Formula Weight: 117.19
MOL File: 4048-33-3.mol

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6-Amino-1-hexanol Property

Melting point:: 54-58 °C (lit.)
Boiling point:: 135-140 °C/30 mmHg (lit.)
Density: 0.8872 (estimate)
refractive index: 1.4444 (estimate)
Flash point:: 133 °C
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
form: Crystals
pka: 15.18±0.10(Predicted)
color: Light yellow to brown
Water Solubility: MISCIBLE
Sensitive: Hygroscopic
BRN: 1732524
Stability:: Hygroscopic. Stable. Incompatible with strong oxidizing agents.
InChI: 1S/C6H15NO/c7-5-3-1-2-4-6-8/h8H,1-7H2
InChIKey: SUTWPJHCRAITLU-UHFFFAOYSA-N
SMILES: NCCCCCCO
CAS DataBase Reference: 4048-33-3(CAS DataBase Reference)
NIST Chemistry Reference: NH2(CH2)6OH(4048-33-3)
EPA Substance Registry System: 1-Hexanol, 6-amino- (4048-33-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
RTECS: MO8840000
F: 3-10
HazardClass: IRRITANT, HYGROSCOPIC
HS Code: 29221990
Storage Class: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Eye Dam. 1
Skin Corr. 1B

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A56353
Product name: 6-Amino-1-hexanol
Purity: 97%
Packaging: 5g
Price: $92.2
Updated: 2026/03/19

Sigma-Aldrich

Product number: A56353
Product name: 6-Amino-1-hexanol
Purity: 97%
Packaging: 25g
Price: $272
Updated: 2026/03/19

TCI Chemical

Product number: A1027
Product name: 6-Amino-1-hexanol
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $42
Updated: 2026/03/19

TCI Chemical

Product number: A1027
Product name: 6-Amino-1-hexanol
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $125
Updated: 2026/03/19

Sigma-Aldrich

Product number: A56353
Product name: 6-Amino-1-hexanol
Purity: 97%
Packaging: 100g
Price: $719
Updated: 2026/03/19

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6-Amino-1-hexanol Chemical Properties,Usage,Production

Chemical Properties

slightly yellow crystalline powder

Uses

6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiprolifer ative and antimigratory activity. Behery, F

Uses

6-Amino-1-hexanol is used as pharmaceutical intermediate.

Uses

6-Amino-1-hexanol can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.

Synthesis

By volume ratio, 1 part of 6-aminohexanoic acid was added to the reactor containing 15 parts of diethyl ether or dry toluene solution At 40 ℃ constant temperature, At 1500rpm / min speed, rapidly injected 2 parts of a solution of sodium borohydride. At 250W, ultrasonic treatment 20min. Then, dropwise under reflux, 8 parts of ethylene glycol solution. Dropwise addition time was 30 minutes. Finally, at 90 ℃ and at a rate of 800rpm/min, maintain temperature under stirring and react for 16 h to obtain the reaction crude product. (2) By the amount of parts count, step (1) preparation of 1 part of the reaction crude was added 6 parts water for hydrolysis. Undrego vacuum distillation, collecting 125 ℃ fraction, to obtain the 6-amino-1-hexanol product.

References

[1] Chemical Communications, 2014, vol. 50, # 76, p. 11211 - 11213
[2] Canadian Journal of Chemistry, 1958, vol. 36, p. 147,149
[3] Angewandte Chemie - International Edition, 2011, vol. 50, # 44, p. 10377 - 10380
[4] Tetrahedron Letters, 2013, vol. 54, # 21, p. 2674 - 2678
[5] Patent: US9463451, 2016, B2. Location in patent: Page/Page column 46-50

6-Amino-1-hexanol Preparation Products And Raw materials

Raw materials

Preparation Products

6-(BOC-AMINO)-HEXYL BROMIDE

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6-Amino-1-hexanol Suppliers

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View Lastest Price from 6-Amino-1-hexanol manufacturers

Career Henan Chemical Co

Product: 6-Amino-1-hexanol 4048-33-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-07

4048-33-3, 6-Amino-1-hexanolRelated Search:

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6-Hydroxy-1-hexylamine

6-Amino-1-hexanol,97%

6-Hexanolamine

6-Aminohexane-1-ol

Hexanolamine

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6-Amino-1-hexanol ,98%

6-AMino-1-hexanol, 94% 10GR

6-Aminohexan-1-ol 98%

6-hydroxyhexylammonium

6-AMino-1-hexanol 97%

6-AMino-1-hexanol, 97.0%(GC&T

RARECHEM AN KA 1117

TIMTEC-BB SBB006584

NH2-(CH2)6-OH

1-Amino-6-hexanol

1-Hexanol, 6-amino-

6-amino-hexano

6-Hydroxyhexylamine

6-Aminohexanol *CAS 4048-33-3*

6-AMINO-1-HEXANOL

6-AMINO-N-CAPROYL ALCOHOL

Amidohexylalkohol

Aminohexyl alcohol

aminohexylalcohol

H2NCH2(CH2)4CH2OH

Hexanol, 6-amino-

H-ACP-OL

H-ACP(6)-OL

H-AHX-OL

6-Amino-1-hexanol, 97%, for synthesis

6-Amino-1-hexanol &gt

6-Amino-1-hexanol USP/EP/BP

6-Amino-2-hexanol

6-Aminohexan-1-ol , 6-Amino-1-hexanol

6-AMINOHEXANOL

6-Aminohexan-1-ol

4048-33-3

H2NCH26OH

AMINE

蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides

Organic Building Blocks

Oxygen Compounds

Building Blocks

Amino Alcohols

蠅-Aminoalkanols

omega-Aminoalkanols

omega-Functional Alkanols, Carboxylic Acids, Amines & Halides

Amino Alcohols

Organic Building Blocks

Oxygen Compounds

bc0001