3-N-Boc-aminopyrrolidine

Product Name: 3-N-Boc-aminopyrrolidine
CAS No.: 99724-19-3
Chemical Name: 3-N-Boc-aminopyrrolidine
Synonyms: TERT-BUTYL PYRROLIDIN-3-YLCARBAMATE;3-(BOC-AMINO)PYRROLIDINE;3-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE;BOC-(+/-)-(3)APYROLIDI;Benzene,1-bromo-6-octyl-;3-N-BOC-AMINO PYRROLIDINE;BOC-(+/-)-3-AMINOPYRROLIDINE;3-N-Boc-aMinoMethypyrrolidine;9H-FLUORENE-2,12-DICARBOXYLICACID;3-Aminopyrrolidine, 3-BOC protected
CBNumber: CB5767919
Molecular Formula: C9H18N2O2
Formula Weight: 186.25
MOL File: 99724-19-3.mol

More

Less

3-N-Boc-aminopyrrolidine Property

Melting point:: 67 °C
Boiling point:: 286.4±29.0 °C(Predicted)
Density: 1.04±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in Methanol(almost transparency).
pka: 12.37±0.20(Predicted)
form: powder to crystal
color: White to Light yellow to Light orange
Sensitive: Air Sensitive
InChIKey: DQQJBEAXSOOCPG-UHFFFAOYSA-N
CAS DataBase Reference: 99724-19-3(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 721832
Product name: 3-(Boc-amino)pyrrolidine
Purity: 95%
Packaging: 1g
Price: $67.76
Updated: 2025/07/31

TCI Chemical

Product number: B1358
Product name: 3-(tert-Butoxycarbonylamino)pyrrolidine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $46
Updated: 2025/07/31

TCI Chemical

Product number: B1358
Product name: 3-(tert-Butoxycarbonylamino)pyrrolidine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $149
Updated: 2025/07/31

TRC

Product number: A614395
Product name: DL-3-(BOC-Amino)pyrrolidine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Oakwood

Product number: 011327
Product name: 3-(tert-Butoxycarbonylamino)pyrrolidine
Packaging: 1g
Price: $10
Updated: 2021/12/16

More

Less

3-N-Boc-aminopyrrolidine Chemical Properties,Usage,Production

Uses

(+/-)-3-(Boc-amino)pyrrolidine is the homochiral starting materials utilised in the synthesis of all of the chiral compounds. Reactant in the peptide activated G-protein coupled receptors test.

Synthesis

99735-30-5

99724-19-3

General procedure for the synthesis of 3-(Boc-amino)pyrrolidine from 1-benzyl-3-(Boc-amino)pyrrolidine: 1-benzyl-3-(Boc-amino)pyrrolidine (15.75 g, 57.0 mmol) was dissolved in a solvent mixture of methanol and tetrahydrofuran (4:1, 114 ml) in a 500 ml reaction vessel. A catalytic amount of 10% palladium/carbon (Pd/C) was added to the solution. The reaction mixture was stirred and reacted for 12 hours under hydrogen atmosphere. Upon completion of the reaction, the palladium/carbon catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to remove the solvent. The resulting residue was purified by silica gel column chromatography to afford 3-(Boc-amino)pyrrolidine (9.51 g, 99% yield). The product was characterized by 1H-NMR (200 MHz, CDCl3): δ 1.41 (s, 9H), 2.26 (m, 2H), 2.55 (m, 3H), 2.74 (m, 1H), 4.84 (br, 1H).LC-MS analysis showed [M+H]+ peak of 187.

References

[1] Patent: WO2008/54154, 2008, A1. Location in patent: Page/Page column 76; 81; 162-163; 168
[2] Patent: WO2007/52938, 2007, A1. Location in patent: Page/Page column 23
[3] Patent: US5281612, 1994, A
[4] Patent: US4604401, 1986, A
[5] Patent: US4617308, 1986, A

3-N-Boc-aminopyrrolidine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Acetonitrile Calcium chloride Di-tert-butyl dicarbonate Sodium borohydride Triethylamine Methanesulfonyl chloride 1,4-Dioxane DL-Aspartic acid Dichloromethane Methanol

Preparation Products

More

Less

3-N-Boc-aminopyrrolidine Suppliers

Americas 1 Canada 1 China 132 Europe 2 Germany 2 India 5 Japan 4 United Kingdom 12 United States 40 Global 199

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

Sphinx Scientific Laboratory, LLC

Tel: --
Fax: --
Email: sales@sphinxscientificlab.com
Country: United States
ProdList: 3343
Advantage: 50

Syntech Labs

Tel: --
Fax: --
Email: info@syntechlabs.com
Country: United States
ProdList: 730
Advantage: 43

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

Chemphtec Corporation

Tel: --
Fax: --
Email: fo@chemphtec.com
Country: United States
ProdList: 2181
Advantage: 58

Tyger Scientific Inc.

Tel: --
Fax: --
Email: sales@tygersci.com
Country: United States
ProdList: 402
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

Leonid Chemicals Private Limited

Tel: --
Fax: --
Email: careers@leonidchemicals.com
Country: United States
ProdList: 1700
Advantage: 43

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

AAT Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@aatpharm.com
Country: United States
ProdList: 209
Advantage: 60

CacheSyn Inc.

Tel: --
Fax: --
Email: info@cachesyn.com
Country: United States
ProdList: 695
Advantage: 50

Bosgen Chemical Inc.

Tel: --
Fax: --
Email: sale@chemapi.com
Country: United States
ProdList: 609
Advantage: 30

Anvia Chemicals, LLC

Tel: --
Fax: --
Email: sales@anviachem.com
Country: United States
ProdList: 3933
Advantage: 0

RnD SciChem, LLC

Tel: --
Fax: --
Email: rndscichem@gmail.com
Country: United States
ProdList: 569
Advantage: 0

Small Molecules, Inc.

Tel: --
Fax: --
Email: sales@small-molecules.com
Country: United States
ProdList: 990
Advantage: 50

Rintech, Inc.

Tel: --
Fax: --
Email: info@rintechinc.com
Country: United States
ProdList: 3416
Advantage: 60

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Focus Synthesis LLC

Tel: --
Fax: --
Email: acd@focussynthesis.com
Country: United States
ProdList: 2487
Advantage: 61

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

CNH Technologies, Inc.

Tel: --
Fax: --
Email: info@cnhtechnologies.com
Country: United States
ProdList: 353
Advantage: 42

Aagile Labs Division of Tyger Scientific

Tel: --
Fax: --
Email: tygersci@yahoo.com
Country: United States
ProdList: 6568
Advantage: 68

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

AstaTech, Inc

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 6371
Advantage: 58

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

EJY Tech, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 448
Advantage: 30

Small Molecules, Inc.

Tel: --
Fax: --
Email: sales@small-molecules.com
Country: United States
ProdList: 1218
Advantage: 30

Atlantic SciTech Group, Inc.

Tel: --
Fax: --
Email: sales@astginc.com
Country: United States
ProdList: 2308
Advantage: 43

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Syntech Development Company

Tel: --
Fax: --
Email: syntechsales@ureach.com
Country: United States
ProdList: 162
Advantage: 30

More

Less

View Lastest Price from 3-N-Boc-aminopyrrolidine manufacturers

Career Henan Chemical Co

Product: 3-N-Boc-aminopyrrolidine 99724-19-3
Price: US $8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-25

99724-19-3, 3-N-Boc-aminopyrrolidineRelated Search:

tert-Butyl peroxybenzoate N-Vinyl-2-pyrrolidone tert-Butyl 4-aminobenzoate tert-Butyl glycinate tert-Butyl carbazate Pyrrolidine 3-Aminopyrrolidine Polyvinylpyrrolidone Povidone iodine tert-Butyl carbamate N-Methyl-2-pyrrolidone DI-TERT-BUTYL ETHER METHYL-2-PYRROLIDONE (4-PHENYLPYRROLIDIN-3-YL)CARBAMIC ACID TERT-BUTYL ESTER 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE (S)-3-(Boc-amino)pyrrolidine 1-BENZYL-3-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE t-butyl chloroformate

tert-butyl 1-aMinopyrrolidine-3-carboxylate

Carbamic acid, N-3-pyrrolidinyl-, 1,1-dimethylethyl ester

N-(3-pyrrolidinyl)carbamic acid tert-butyl ester

N-pyrrolidin-3-ylcarbamic acid tert-butyl ester

tert-butyl N-pyrrolidin-3-ylcarbamate

3-(tert-Butoxycarbonylamino)pyrrolidi

tert-butyl pyrrolidin-3-ylcarbamate99724-19-3

3-(BOC-AMINO)PYRROLIDINE

3-N-BOC-AMINO PYRROLIDINE

3-PYRROLIDINYL-CARBAMIC ACID TERT-BUTYL ESTER

3-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE

BOC-(+/-)-3-AMINOPYRROLIDINE

BOC-(+/-)-(3)APYROLIDI

TERT-BUTYL PYRROLIDIN-3-YLCARBAMATE

PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER

N-3-(+/-)-T-BUTOXYCARBONYL-3-AMINOPYRROLIDINE

3-(BOC-AMINO)PYRROLIDINE HYDROCHLORIDE

3-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE 98+%

3-Aminopyrrolidine, 3-BOC protected

Pyrrolidine-3-ylcarbamic acid tert-butyl ester

3-(tert-Butoxycarbonylamino) pyrrolidine ,96%

tert-Butyl pyrrolidin-3-ylcarbamate, 3-[(tert-Butoxycarbonyl)amino]pyrrolidine

3-N-Boc-aMinoMethypyrrolidine

3-(tert-Butoxycarbonylamino)pyrrolidine &gt

Benzene,1-bromo-6-octyl-

9H-FLUORENE-2,12-DICARBOXYLICACID

3-N-Boc-amino pyrrolidine, CAS 99724-19-3

99724-19-3

3-Aminopyrrolidines

3-Aminopyrrolidines (Racemic)

3-Aminopyrrolidines

3-Aminopyrrolidines (Racemic)

Amines

Pyrrolidines

pharmacetical

Pyrrole&Pyrrolidine&Pyrroline