ChemicalBook > CAS DataBase List > E3 ligase Ligand-Linker Conjugates 29
E3 ligase Ligand-Linker Conjugates 29
- Product Name
- E3 ligase Ligand-Linker Conjugates 29
- CAS No.
- 2098836-63-4
- Chemical Name
- E3 ligase Ligand-Linker Conjugates 29
- Synonyms
- VH032-thiol-C6-NH2;VHL Ligand-Linker Conjugates 14;E3 ligase Ligand-Linker Conjugates 29;L-Prolinamide, N-acetyl-3-[(6-aminohexyl)thio]-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-[(2R)-3-[(6-aminohexyl)sulfanyl]-2-acetamido-3-methylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CBNumber
- CB58054806
- Molecular Formula
- C29H43N5O4S2
- Formula Weight
- 589.82
- MOL File
- 2098836-63-4.mol
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E3 ligase Ligand-Linker Conjugates 29 Property
- Boiling point:
- 868.6±65.0 °C(Predicted)
- Density
- 1.232±0.06 g/cm3(Predicted)
- pka
- 14.05±0.40(Predicted)
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E3 ligase Ligand-Linker Conjugates 29 Chemical Properties,Usage,Production
Uses
VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.
IC 50
VHL
References
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
E3 ligase Ligand-Linker Conjugates 29 Preparation Products And Raw materials
Raw materials
Preparation Products
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E3 ligase Ligand-Linker Conjugates 29 Suppliers
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2098836-63-4, E3 ligase Ligand-Linker Conjugates 29Related Search:
VH032 thiol
VH 032 phenol-linker 1
HaloPROTAC 2
VH 101, phenol
(2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide