ChemicalBook > CAS DataBase List > 4,4'-propylenebis(piperazine-2,6-dione)

4,4'-propylenebis(piperazine-2,6-dione)

Product Name
4,4'-propylenebis(piperazine-2,6-dione)
CAS No.
21416-67-1
Chemical Name
4,4'-propylenebis(piperazine-2,6-dione)
Synonyms
Troxozone;RAZOXANUM;Propyliminum;rac-Dexrazoxane;4,4'-(Propane-1,2-diyl);bis(piperazine-2,6-dione);-propylenebis(piperazine-2,6-dione);4,4'-propylenebis(piperazine-2,6-dione);4,4'-Propane-1,2-diyldipiperazine-2,6-dione;4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
CBNumber
CB5918838
Molecular Formula
C11H16N4O4
Formula Weight
268.27
MOL File
21416-67-1.mol
More
Less

4,4'-propylenebis(piperazine-2,6-dione) Property

Melting point:
237-239°
Boiling point:
411.43°C (rough estimate)
Density 
1.2576 (rough estimate)
refractive index 
1.6081 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: soluble40mg/mL
form 
solid
pka
11.00±0.20(Predicted)
color 
White to off-white
Water Solubility 
3g/L(25 ºC)
More
Less

Safety

WGK Germany 
3
RTECS 
TL6389900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R8657
Product name
Razoxane
Purity
>98% (HPLC)
Packaging
5mg
Price
$112
Updated
2024/03/01
TRC
Product number
R128060
Product name
Razoxane
Packaging
1g
Price
$715
Updated
2021/12/16
Matrix Scientific
Product number
076182
Product name
4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
Purity
95+%
Packaging
250mg
Price
$907
Updated
2021/12/16
AK Scientific
Product number
E393
Product name
Razoxane
Packaging
1g
Price
$1063
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008266
Product name
RAZOXANE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
More
Less

4,4'-propylenebis(piperazine-2,6-dione) Chemical Properties,Usage,Production

Uses

Razoxane is an inhibitor of Topo II.

Definition

ChEBI: Razoxane is a N-alkylpiperazine.

Safety Profile

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

4,4'-propylenebis(piperazine-2,6-dione) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4,4'-propylenebis(piperazine-2,6-dione) Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
DebyeTec.com Inc.
Tel
18086626237 18086626237
Fax
qq:2693528373
Email
sales@debyesci.com
Country
China
ProdList
2645
Advantage
56
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15084
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
TOSUN PHARM
Tel
020-61855200 13326451905
Email
260366801@qq.com
Country
China
ProdList
7796
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58

21416-67-1, 4,4'-propylenebis(piperazine-2,6-dione) Related Search:


  • 4,4'-propylenebis(piperazine-2,6-dione)
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • RAZOXANUM
  • 4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
  • 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
  • Propyliminum
  • 4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
  • 4,4'-(Propane-1,2-diyl)
  • bis(piperazine-2,6-dione)
  • Troxozone
  • -propylenebis(piperazine-2,6-dione)
  • 4,4'-propylenebis(piperazine-2,6-dione) USP/EP/BP
  • 4,5,9,10-Pyrenetetrone,2,7-bis(1,6-dimethylethyl)-
  • rac-Dexrazoxane
  • ICRF 159,ICRF159,ICRF-159,Topoisomerase II Inhibitor,Razoxane,RCC,Inhibitor,Topoisomerase,renal cell carcinoma,inhibit
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • Razoxane (ICRF-159), PDGF beta-receptor inhibitor
  • 21416-67-1
  • Angiogenesis and metastasis.